Anticholinesterase activity of 3-formylchromone derivatives

2021 ◽  
Vol 24 (10) ◽  
pp. 31-35
Author(s):  
D.I. Pozdnyakov
2019 ◽  
Vol 484 (1) ◽  
pp. 104-108
Author(s):  
G. F. Makhaeva ◽  
E. F. Shevtsova ◽  
N. P. Boltneva ◽  
N. V. Kovaleva ◽  
E. V. Rudakova ◽  
...  

This study presents the synthesis of binary tetrohydro-γ-carbolines with ditriazol spacers of varying length, which exhibit anticholinesterase and antioxidant activity, as compared to the original Dimebon prototype. Anticholinesterase activity suggests the potential ability of the new compounds to block β-amyloid aggregation induced by anticholinesterase, making them promising candidates for further research preparations for the treatment of Alzheimer's disease. Particular attention should be paid to the conjugate with an intertriazol hexamethylene spacer, which can be regarded as the leading compound in this series.


2010 ◽  
Vol 7 (1) ◽  
pp. 1-4 ◽  
Author(s):  
Jiri Binder ◽  
Martin Paar ◽  
Daniel Jun ◽  
Miroslav Pohanka ◽  
Martina Hrabinova ◽  
...  

Toxicon ◽  
1977 ◽  
Vol 15 (1) ◽  
pp. 63-64 ◽  
Author(s):  
M.F. El-Asmar ◽  
M. Ismail ◽  
Kh. Ghoneim ◽  
O.H. Osman

2011 ◽  
Vol 28 (1) ◽  
pp. 218-222 ◽  
Author(s):  
Eduardo Luis Konrath ◽  
María Gabriela Ortega ◽  
Sérgio de Loreto Bordignon ◽  
Miriam Anders Apel ◽  
Amélia Teresinha Henriques ◽  
...  

Author(s):  
Letícia Carlesso Soprani ◽  
Jean P. de Andrade ◽  
Vanessa Dias dos Santos ◽  
Anderson Alves-Araújo ◽  
Jaume Bastida ◽  
...  

2017 ◽  
Vol 113 ◽  
pp. 119-127 ◽  
Author(s):  
B. Bozkurt ◽  
G. Coban ◽  
G.I. Kaya ◽  
M.A. Onur ◽  
N. Unver-Somer

2012 ◽  
Vol 22 (2) ◽  
pp. 374-380 ◽  
Author(s):  
Rodrigo S. Cabral ◽  
Maura C. Sartori ◽  
Inês Cordeiro ◽  
Carmen L. Queiroga ◽  
Marcos N. Eberlin ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document