scholarly journals Application of Multimodal MRI in Cerebral Infarction

2020 ◽  
Vol 8 (2) ◽  
Author(s):  
Mengjiao Wei

 Symptomatic atherosclerotic intracranial artery stenosis often causes ischemic cerebral infarction or transient ischemic attack in the stenosis area. Early detection of cerebral infarction and evaluation of ischemic penumbra and hemodynamics in the infarct area Information plays an extremely important role in clinical treatment and prognosis. This article briefly introduces the application of multimodal MRI in cerebral infarction.

2021 ◽  
Vol 11 (2) ◽  
pp. 590-594
Author(s):  
Aixia Song ◽  
Jing Chen ◽  
Yan Sun ◽  
Xiaoqin Wang ◽  
Jichao Zhang ◽  
...  

Objective: To investigate the clinical effects of intravenous thrombolysis in the treatment of TIA (Transient Ischemic Attack) and cerebral infarction with multimodal MRI (magnetic resonance imaging), and to provide a reference for clinical diagnosis and treatment. Methods: Patients with acute cerebral infarction diagnosed and treated with intravenous thrombolysis were enrolled in the study. Multimodal MRI was performed to determine the location and type of cerebral infarction. Based on routine treatment and care, the rt-PA (Recombinant Tissue Plasminogen Activator) intravenous thrombolytic therapy was applied. The NIHSS (National Institutes of Health Stroke Scale) scores of patients before and after treatment were evaluated and compared to analyze the neurological prognosis. Results: The NIHSS scores after treatment were significantly lower than those before treatment, and the neurological prognosis was good. Three different forms of ACVS (asymmetric cortical venous signs) after treatment could be observed by SWI (drug-sensitive weighted imaging) images, which could help to assess the prognosis. Conclusion: Multimodal MRI could evaluate the type and severity of acute cerebral infarction. The rt-PA intravenous thrombolytic therapy could effectively promote the recovery of neurological functions in patients with cerebral infarction, which was worthy of clinical promotion.


2012 ◽  
Vol 34 (1) ◽  
pp. 185-190 ◽  
Author(s):  
G. Ssi-Yan-Kai ◽  
N. Nasr ◽  
A. Faury ◽  
I. Catalaa ◽  
C. Cognard ◽  
...  

2013 ◽  
Vol 9 (7) ◽  
pp. 895-901 ◽  
Author(s):  
Hyun-Wook Nah ◽  
Sun U. Kwon ◽  
Dong-Wha Kang ◽  
Deok-Hee Lee ◽  
Jong S. Kim

1993 ◽  
Vol 3 (1) ◽  
pp. 23-28 ◽  
Author(s):  
Askiel Bruno ◽  
Lynn Jeffries ◽  
Elizabeth LaKind ◽  
Clifford Qualls

Stroke ◽  
1981 ◽  
Vol 12 (2) ◽  
pp. 167-172 ◽  
Author(s):  
A Murai ◽  
T Tanaka ◽  
T Miyahara ◽  
M Kameyama

2020 ◽  
Author(s):  
Hao Wang ◽  
Hao Lu ◽  
Xiao-Meng Zhang ◽  
Ken-ichiro Goto ◽  
Eiichi Kobayashi ◽  
...  

Abstract Background: Ischemic stroke, such as transient ischemic attack (TIA) and acute-phase cerebral infarction (aCI) , are the serious problems in the aging society. Therefore, development of biomarkers for TIA and aCI are attempted. Methods: Candidate antigens recognized by IgG autoantibodies in the serum of 19 TIA patients were screened by a human aortic endothelial cell cDNA library. Serum antibody levels against the antigens were examined by amplified luminescent proximity homogeneous assay-linked immunosorbent assay (AlphaLISA) in healthy donor (HD), TIA, and aCI cohorts ( n = 285, 92 and 529). The antibody levels in the sera of the Japan Public Health Center-based Prospective Cohort Study (JPHC) from 1991 to 1993 was also examined. Results: Aldolase A, fructose-bisphosphate (ALDOA) and fumarate hydratase (FH) were identified as the candidate antigens. AlphaLISA revealed that the levels of anti-ALDOA antibodies (ALDOA-Abs) and anti-FH antibodies (FH-Abs) were both higher in patients with TIA or aCI than those in HDs ( P < 0.05). The levels of ALDOA-Abs [odds ratio (OR): 2.46, P = 0.0050] and FH-Abs (OR: 2.49, P = 0.0037) were independent predictors of TIA by multivariate logistic regression analysis. The case-control study showed the levels of ALDOA-Abs (OR: 2.50, P < 0.01) and FH-abs (OR: 2.60, P < 0.01) were associated with risk of aCI. Correlation analysis demonstrated that both ALDOA-Abs and FH-Abs were well associated with hypertension, coronary heart disease and habitual smoking. These antibody levels were also correlated well with maximum intima-media thickness, which reflects atherosclerotic stenosis. Conclusions: ALDOA-Abs and FH-Abs can serve as novel potential biomarkers for prediction of atherosclerotic TIA and aCI.


Neurology ◽  
1995 ◽  
Vol 45 (3) ◽  
pp. 428-431 ◽  
Author(s):  
M. Eliasziw ◽  
J. Y. Streifler ◽  
J. D. Spence ◽  
A. J. Fox ◽  
V. C. Hachinski ◽  
...  

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