Induction of labor is often used in modern obstetrics. Labor induction methods are quite diverse. Proposed by a large number of labor induction methods, such as medication and non-medication. The growth rate of induced births dictates the need to find an effective and safe method of labor induction. One of the most studied inductors reduce the myometrium are prostaglandins. The review of literature presents data on the mechanism of action of prostaglandin E1 on the myometrium cell, given the characteristics of various methods of labor induction with a synthetic analogue of prostaglandin E1 Misoprostol.