Effect of Furosemide Upon Morphology of Hair Bundles in Guinea Pig Cochlear Hair Cells

1990 ◽  
Vol 109 (1-2) ◽  
pp. 49-56 ◽  
Author(s):  
S. D. Comis ◽  
M. P. Osborne ◽  
D. J. R. Jeffries
Keyword(s):  
Guinea Pig ◽  
Hair Cells ◽  
Cochlear Hair Cells ◽  
Hair Bundles

Apoptosis of guinea pig cochlear hair cells following chronic aminoglycoside treatment

1998 ◽  
Vol 255 (3) ◽  
pp. 127-131 ◽  
Author(s):  
T. Nakagawa ◽  
H. Yamane ◽  
M. Takayama ◽  
K. Sunami ◽  
Y. Nakai
Keyword(s):  
Guinea Pig ◽  
Hair Cells ◽  
Cochlear Hair Cells

scholarly journals Rapid mechanical stimulation of inner-ear hair cells by photonic pressure

2021 ◽  
Author(s):  
Sanjeewa Abeytunge ◽  
Francesco Gianoli ◽  
A.J. Hudspeth ◽  
Andrei S. Kozlov
Keyword(s):  
Inner Ear ◽  
Hair Cells ◽  
Dynamic Range ◽  
Auditory Stimuli ◽  
Frequency Range ◽  
Mechanical Vibrations ◽  
Cochlear Hair Cells ◽  
Broad Dynamic Range ◽  
Hair Bundles ◽  
Stimulation Of

AbstractHair cells, the receptors of the inner ear, detect sounds by transducing mechanical vibrations into electrical signals. From the top surface of each hair cell protrudes a mechanical antenna, the hair bundle, which the cell uses to detect and amplify auditory stimuli, thus sharpening frequency selectivity and providing a broad dynamic range. Current methods for mechanically stimulating hair bundles are too slow to encompass the frequency range of mammalian hearing and are plagued by inconsistencies. To overcome these challenges, we have developed a method to move individual hair bundles with photonic force. This technique uses an optical fiber whose tip is tapered to a diameter of a few micrometers and endowed with a ball lens to minimize divergence of the light beam. Here we describe the fabrication, characterization, and application of this optical system and demonstrate the rapid application of photonic force to vestibular and cochlear hair cells.

Kanamycin-induced changes in cochlear hair cells of the guinea pig

1966 ◽  
Vol 72 (4) ◽  
pp. 543-561 ◽  
Author(s):  
P. -G. Lundquist ◽  
J. Wers�ll
Keyword(s):  
Guinea Pig ◽  
Hair Cells ◽  
Cochlear Hair Cells ◽  
Induced Changes

scholarly journals Changes in Guinea Pig Cochlear Hair Cells after Sound Conditioning and Noise Exposure

2008 ◽  
Vol 50 (5) ◽  
pp. 373-379 ◽  
Author(s):  
Hongyan Zuo ◽  
Bo Cui ◽  
Xiaojun She ◽  
Mingquan Wu
Keyword(s):  
Guinea Pig ◽  
Hair Cells ◽  
Noise Exposure ◽  
Cochlear Hair Cells

scholarly journals Rapid mechanical stimulation of inner-ear hair cells by photonic pressure

eLife ◽  
2021 ◽  
Vol 10 ◽  
Author(s):  
Sanjeewa Abeytunge ◽  
Francesco Gianoli ◽  
A James Hudspeth ◽  
Andrei Kozlov
Keyword(s):  
Inner Ear ◽  
Hair Cells ◽  
Dynamic Range ◽  
Auditory Stimuli ◽  
Frequency Range ◽  
Mechanical Vibrations ◽  
Cochlear Hair Cells ◽  
Broad Dynamic Range ◽  
Hair Bundles ◽  
Stimulation Of

Hair cells, the receptors of the inner ear, detect sounds by transducing mechanical vibrations into electrical signals. From the top surface of each hair cell protrudes a mechanical antenna, the hair bundle, which the cell uses to detect and amplify auditory stimuli, thus sharpening frequency selectivity and providing a broad dynamic range. Current methods for mechanically stimulating hair bundles are too slow to encompass the frequency range of mammalian hearing and are plagued by inconsistencies. To overcome these challenges, we have developed a method to move individual hair bundles with photonic force. This technique uses an optical fiber whose tip is tapered to a diameter of a few micrometers and endowed with a ball lens to minimize divergence of the light beam. Here we describe the fabrication, characterization, and application of this optical system and demonstrate the rapid application of photonic force to vestibular and cochlear hair cells.

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