Influence of the Upper Respiratory Tract Infection on Tubal Compliance in Children with Otitis Media with Effusion

1997 ◽  
Vol 117 (4) ◽  
pp. 574-577 ◽  
Author(s):  
Makoto Miura ◽  
Haruo Takahashi ◽  
Iwao Honjo ◽  
Seishi Hasebe ◽  
Makito Tanabe
2021 ◽  
Vol 22 (15) ◽  
pp. 7868
Author(s):  
Su Young Jung ◽  
Dokyoung Kim ◽  
Dong Choon Park ◽  
Sung Soo Kim ◽  
Tong In Oh ◽  
...  

Otitis media is mainly caused by upper respiratory tract infection and eustachian tube dysfunction. If external upper respiratory tract infection is not detected early in the middle ear, or an appropriate immune response does not occur, otitis media can become a chronic state or complications may occur. Therefore, given the important role of Toll-like receptors (TLRs) in the early response to external antigens, we surveyed the role of TLRs in otitis media. To summarize the role of TLR in otitis media, we reviewed articles on the expression of TLRs in acute otitis media (AOM), otitis media with effusion (OME), chronic otitis media (COM) with cholesteatoma, and COM without cholesteatoma. Many studies showed that TLRs 1–10 are expressed in AOM, OME, COM with cholesteatoma, and COM without cholesteatoma. TLR expression in the normal middle ear mucosa is absent or weak, but is increased in inflammatory fluid of AOM, effusion of OME, and granulation tissue and cholesteatoma of COM. In addition, TLRs show increased or decreased expression depending on the presence or absence of bacteria, recurrence of disease, tissue type, and repeated surgery. In conclusion, expression of TLRs is associated with otitis media. Inappropriate TLR expression, or delayed or absent induction, are associated with the occurrence, recurrence, chronicization, and complications of otitis media. Therefore, TLRs are very important in otitis media and closely related to its etiology.


Author(s):  
Hubballi Ravi Kishore ◽  
Reshma P. R.

<p><strong>Background:</strong> Chronic otitis media equates with the term chronic suppurative otitis media that is no longer advocated as it is not necessarily a result of the gathering of pus. Incidence of this disease is higher in developing countries especially among lower socioeconomic society because of malnutrition, overcrowding, poor hygiene, inadequate health care facility and recurrent upper respiratory tract infection.</p><p><strong>Methods: </strong>Eighty patients with chronic otitis media were included. After obtaining written and informed consent, they were subjected to detailed history taking and examination. Various risk factors of chronic otitis media and the morbidity caused by the disease were studied. Data was analyzed using IBM SPSS version 22.<strong></strong></p><p><strong>Results: </strong>The most common age group was 21-30 years with male predominance. Central perforation was the most common type of perforation. Various factors like low socioeconomic status, rural setup, overcrowding, malnutrition, indoor cooking, recurrent acute otitis media, recurrent upper respiratory tract infection, naso-respiratory allergies, habit of swimming, taking bath in pond, ear probing were found to cause the onset of the disease and worsen of the disease process.<strong></strong></p><p><strong>Conclusions: </strong>Chronic otitis media results in various morbidity including increased financial burden, restricts daily activities, hence affects the psychological mindset and lowers the confidence of the patient giving them a feeling of social outcast. A proper awareness must be spread regarding these factors, maintaining personal hygiene, improving nutrition and immunity. An immediate consultation with the otorhinolaryngologist will reduce the disease progression and hence the complications. <strong></strong></p>


PLoS ONE ◽  
2017 ◽  
Vol 12 (7) ◽  
pp. e0180630 ◽  
Author(s):  
Tasnee Chonmaitree ◽  
Kristofer Jennings ◽  
Georgiy Golovko ◽  
Kamil Khanipov ◽  
Maria Pimenova ◽  
...  

2021 ◽  
Vol 31 (Supplement_2) ◽  
Author(s):  
Tatiana Marques ◽  
Carolina Fernandes ◽  
Carla Moura ◽  
António Miguéis

Abstract Background Acute otitis media (AOM) is one of the most common diseases in childhood, affecting approximately 50% of all children. The most common age range to develop AOM is 3–24 months, due to a current or recent upper respiratory tract infection, which induces the eustachian tube to develop fluid or secretion from the middle ear inflammation. The acute onset of symptoms in older children is characterized by otalgia and rubbing of the ear, however, AOM in younger children include nonspecific symptoms such as fever, irritability, or poor feeding, being unreliable guides to the diagnosis. Thus, the underdiagnosis of AOM can lead to serious complications include acute mastoiditis or meningitis. Hence, the study aims to investigate the prevalence of AOM in children younger than four years. Methods A cross-sectional study was conducted in a kindergarten, being enrolled children between 1 and 4 years. The protocol included otoscopy and tympanometry. Results A total of 23 children with a mean age of 2-year-old (SD = 0.88) were evaluated, with 17 children (34.8%) diagnosed with AOM, of whom 2 (15.4%) had unilateral alterations and 11 (84.6%) bilateral alterations. Conclusions AOM is one of the main childhood pathologies, affecting approximately 34.8% of younger children. Success in decreasing prevalence of AOM will depend on prevention of nasopharyngeal pathogen colonization, as well as decrease of viral upper respiratory tract infection, which can be reduced with nasal saline irrigation, a clinical and economic therapeutic approach.


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