Maximum Length Sequences - A Fast Method for Measuring Brain-Stem-Evoked Responses

1982 ◽  
Vol 21 (3) ◽  
pp. 242-250 ◽  
Author(s):  
U. Eysholdt ◽  
Chr. Schreiner
Keyword(s):  
Brain Stem ◽  
Maximum Length ◽  
Fast Method ◽  
Evoked Responses

Brain Stem Auditory Evoked Responses

2009 ◽  
Vol 62 (1) ◽  
pp. 64-64
Author(s):  
Khalil Kayed ◽  
Reidar Kloster
Keyword(s):  
Brain Stem ◽  
Evoked Responses ◽  
Auditory Evoked Responses

Carboplatin ototoxicity: an animal model

1993 ◽  
Vol 107 (7) ◽  
pp. 585-589 ◽  
Author(s):  
Mark Wake ◽  
Sachio Takeno ◽  
Danyl Ibrahim ◽  
Robert Harrison ◽  
Richard Mount
Keyword(s):  
Animal Model ◽  
Light Microscopy ◽  
Hair Cell ◽  
Brain Stem ◽  
Auditory System ◽  
Hair Cells ◽  
Afferent Input ◽  
Evoked Responses ◽  
Auditory Thresholds ◽  
Scanning Electronmicroscopy

A new animal model of ototoxicity is presented using intravenous carboplatin in adult chinchillas. A range of physiological and morphological effects was produced using doses calculated from the recommended therapeutic range (200–400 mg/m2). Auditory thresholds to tone pips stimuli were monitored using brain stem evoked responses (ABR). Cochlear histopathology was studied by light microscopy (LM) and ultrstructural hair cell abnormalities investigated with scanning electronmicroscopy (SEM). Carboplatin in this animal model predominantly affected the inner hair cells. This may provide an important model for the study of selective loss of the main afferent input in the auditory system.

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