Quality control material containing hemoglobin for blood gas and pH measurement: Improvement of the stability of stroma-free hemoglobin solution

1987 ◽  
Vol 47 ◽  
pp. 83-92 ◽  
Author(s):  
R. Sprokholt ◽  
S. Van Ooik ◽  
R. A.M. Van Den Camp ◽  
B. N. Bouma ◽  
W. G. Zijlstra ◽  
...  
Keyword(s):  
Quality Control ◽  
Ph Measurement ◽  
Blood Gas ◽  
Quality Control Material ◽  
Free Hemoglobin ◽  
Hemoglobin Solution ◽  
Control Material ◽  
The Stability

Preparing a quality control material for blood gases, pH and hemoglobinometry using stroma-free hemoglobin solution

1987 ◽  
Vol 47 (sup188) ◽  
pp. 93-99 ◽  
Author(s):  
R. Sprokholt ◽  
S. Van Ooik ◽  
R. A.M. Van Den Camp ◽  
B. N. Bouma ◽  
W. G. Zijlstra ◽  
...  
Keyword(s):  
Quality Control ◽  
Blood Gases ◽  
Quality Control Material ◽  
Free Hemoglobin ◽  
Hemoglobin Solution ◽  
Control Material

Evaluation of a quality control material containing hemoglobin for blood gas and pH measurement

1987 ◽  
Vol 47 (sup188) ◽  
pp. 101-112 ◽  
Author(s):  
R. Sprokholt ◽  
S. Van Ooik ◽  
R. A.M. Van Den Camp ◽  
B. N. Bouma ◽  
W. G. Zijlstra ◽  
...  
Keyword(s):  
Quality Control ◽  
Ph Measurement ◽  
Blood Gas ◽  
Quality Control Material ◽  
Control Material

Evaluation of a quality control material containing hemoglobin for blood gas and pH measurement

1987 ◽  
Vol 47 ◽  
pp. 101-112 ◽  
Author(s):  
R. Sprokholt ◽  
S. Van Ooik ◽  
R. A.M. Van Den Camp ◽  
B. N. Bouma ◽  
W. G. Zijlstra ◽  
...  
Keyword(s):  
Quality Control ◽  
Ph Measurement ◽  
Blood Gas ◽  
Quality Control Material ◽  
Control Material

Lyophilized bovine hemoglobin as a possible reference material for the determination of hemoglobin derivatives in human blood

1998 ◽  
Vol 44 (11) ◽  
pp. 2331-2339 ◽  
Author(s):  
Bart H A Maas ◽  
Anneke Buursma ◽  
Rob A J Ernst ◽  
Anton H J Maas ◽  
Willem G Zijlstra
Keyword(s):  
Quality Control ◽  
Bovine Hemoglobin ◽  
Wavelength Selection ◽  
Quality Control Material ◽  
Hemoglobin Solution ◽  
Control Material ◽  
Hemoglobin Derivatives ◽  
Target Values ◽  
Specific Factors

Abstract We investigated the suitability of a lyophilized bovine hemoglobin (LBH) preparation containing various fractions of oxyhemoglobin (O2Hb), carboxyhemoglobin (COHb), and methemoglobin (MetHb) for quality assessment in multicomponent analysis (MCA) of hemoglobin derivatives. It was demonstrated that a stable preparation of these components after reconstitution yields a hemoglobin solution that is spectrophotometrically equivalent with a fresh bovine hemoglobin solution. The preparation was found to be stable for at least 1 year when it is kept at 2–8 °C and for 1 h after reconstitution. We determined the fractions of O2Hb, COHb, and MetHb of several LBH preparations, using the complete spectra of 480–650 nm with 2-nm intervals and absorptivities as determined for pure LBH solutions. A field trial involving various types of multiwavelength hemoglobin photometers showed the suitability of LBH as a quality-control material. Computer models of the various common multiwavelength hemoglobin photometers may be useful for establishing more accurate target values of LBH preparations for each type of photometer and for studying the importance of the influence of specific factors such as wavelength selection, absorptivity values, and interfering dyes.

Postmortem Vitreous Humor Analysis in Dogs, Cats and Horses

2020 ◽  
Author(s):  
Adam W Stern ◽  
Manavi Muralidhar
Keyword(s):  
Quality Control ◽  
Vitreous Humor ◽  
Limited Information ◽  
Quality Control Material ◽  
Forensic Pathologist ◽  
Control Material ◽  
Species Analysis ◽  
Postmortem Chemistry ◽  
The Stability ◽  
Death Investigation

Abstract Postmortem chemistry can be a useful ancillary technique that the forensic pathologist can use during a death investigation. In stark contrast, there is limited information available for use of postmortem vitreous humor analysis in animals. In order to use postmortem vitreous humor in veterinary forensic investigations, validation of a method to analyze vitreous humor is required. The goal of this study was to determine the precision, bias, TEobs and sigma (σ) of the Element DC chemistry analyzer; assess its precision using the vitreous humor collected postmortem from dogs, cats and horses and assess the stability of postmortem vitreous humor from all the three species. Analysis of quality control material (QCM) and pooled vitreous humor samples for the three species was used to test for sodium (Na), chloride (Cl), potassium (K), magnesium (Mg), creatinine (Crea) and blood/vitreous urea nitrogen. Analysis of QCM showed that the Element DC was both precise and accurate. When analyzing the pooled vitreous humors, most within-run coefficients of variance (CVs) were found to be <5% and the between-run CVs for five out of six analytes were found to be <5% for dogs, cats and horses. In all the three species, the capped samples of vitreous humor were stable out of refrigeration for up to 5 h. The results of this study show that the Element DC can successfully be used to analyze the postmortem vitreous humor from dogs, cats and horses.

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