Induction of Matrix Metalloproteinase-8 in Human Fibroblasts by Basic Calcium Phosphate and Calcium Pyrophosphate Dihydrate Crystals: Effect of Phosphocitrate

2001 ◽  
Vol 42 (1) ◽  
pp. 1-12 ◽  
Author(s):  
Paul M. Reuben ◽  
Leonor Wenger ◽  
Marcella Cruz ◽  
Herman S. Cheung
Keyword(s):  
Calcium Phosphate ◽  
Matrix Metalloproteinase ◽  
Human Fibroblasts ◽  
Calcium Pyrophosphate ◽  
Calcium Pyrophosphate Dihydrate ◽  
Basic Calcium Phosphate ◽  
Pyrophosphate Dihydrate ◽  
Calcium Pyrophosphate Dihydrate Crystals

Tumourous Deposition of Calcium Pyrophosphate Dihydrate Crystals in the Wrist

1991 ◽  
Vol 16 (2) ◽  
pp. 219-222 ◽  
Author(s):  
I. OHSHIO ◽  
T. OGINO ◽  
S. SATOH ◽  
M. KONARI ◽  
K. NAGASHIMA
Keyword(s):  
Calcium Carbonate ◽  
Calcium Phosphate ◽  
Calcium Pyrophosphate ◽  
Calcium Pyrophosphate Dihydrate ◽  
Pyrophosphate Dihydrate ◽  
Calcium Pyrophosphate Dihydrate Crystals ◽  
Palmar Aspect

A 63-year-old man had a tumourous deposition of calcium pyrophosphate dihydrate crystals in the palmar aspect of the wrist. Traumatic micro-fracture or osteoarthritis was thought to have triggered the deposition of these crystals. It should be possible to differentiate the lesion clinically and radiologically from tumoural calcinosis, in which the deposits consist of calcium carbonate and/or calcium phosphate.

Crystal-induced musculoskeletal disease

2018 ◽  
pp. 277-292
Author(s):  
Gavin Clunie ◽  
Nick Wilkinson ◽  
Elena Nikiphorou ◽  
Deepak R. Jadon
Keyword(s):  
Calcium Phosphate ◽  
Clinical Manifestations ◽  
Calcium Pyrophosphate ◽  
Classification Criteria ◽  
Musculoskeletal Disease ◽  
Calcium Pyrophosphate Dihydrate ◽  
Basic Calcium Phosphate ◽  
Community Settings ◽  
Pyrophosphate Dihydrate ◽  
User Friendly

This chapter describes crystal-induced musculoskeletal disease, which encompasses gout, hyperuricaemia, calcium pyrophosphate dihydrate disease, basic calcium phosphate-associated disease, and calcium oxalate arthritis. Their epidemiology, aetiopathogenesis, classification criteria, presenting features, clinical manifestations, and management are discussed. Diet, lifestyle, non-pharmacological and pharmacological approaches to their management are considered. User-friendly algorithms for the management of gout and calcium pyrophosphate dihydrate disease are provided, allowing both rheumatologists and non-rheumatologists to confidently manage these diseases in clinic, ward, or community settings.

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