18β-Glycyrrhetinic acid fromlicorice rootimpairs dendritic cells maturation and Th1 immune responses

2013 ◽  
Vol 35 (3) ◽  
pp. 329-335 ◽  
Author(s):  
Mi Eun Kim ◽  
Hyung Keun Kim ◽  
Dong Hwan Kim ◽  
Ju Hwa Yoon ◽  
Jun Sik Lee
2003 ◽  
Vol 170 (9) ◽  
pp. 4457-4464 ◽  
Author(s):  
Ingrid L. Dodge ◽  
Michelle Woldemar Carr ◽  
Manuela Cernadas ◽  
Michael B. Brenner

2012 ◽  
Vol 189 (6) ◽  
pp. 3092-3103 ◽  
Author(s):  
Xisheng Wang ◽  
Peter F. Barnes ◽  
Fangfang Huang ◽  
Ivana B. Alvarez ◽  
Pierre F. Neuenschwander ◽  
...  

Author(s):  
Yosef Ellenbogen ◽  
Rodrigo Jiménez-Saiz ◽  
Paul Spill ◽  
Derek K. Chu ◽  
Susan Waserman ◽  
...  

In contrast to Th1 immune responses against pathogenic viruses and bacteria, the incipient events that generate Th2 responses remain less understood. Part of the difficulty in identifying universal operating principles stems from the diversity of entities against which cellular and molecular Th2 responses are produced. Indeed, such responses are launched towards harmful macroscopic parasites and noxious substances such as venoms but also against largely innocuous allergens. This suggests that the canonical understanding about sensing and recognition applied to Th1 responses may not be translatable to Th2 responses. This review will discuss processes and signals known to occur in Th2 responses, particularly in the context of food allergy. We propose that perturbations of homeostasis at barrier sites induced by external or internal subverters that either activate the immune system or lower its threshold activation are the major requirement for allergic sensitization. Innate signals produced in the tissue under these conditions equip dendritic cells with a program that shapes an adaptive Th2 response.


2014 ◽  
Vol 192 (5) ◽  
pp. 2271-2279 ◽  
Author(s):  
Masoud Akbari ◽  
Kiri Honma ◽  
Daisuke Kimura ◽  
Mana Miyakoda ◽  
Kazumi Kimura ◽  
...  

2015 ◽  
Vol 24 (4) ◽  
pp. 1533-1540 ◽  
Author(s):  
Eui-Baek Byun ◽  
Nak-Yun Sung ◽  
Sang-Hyun Park ◽  
Chulhwan Park ◽  
Eui-Hong Byun

2011 ◽  
Vol 90 (3) ◽  
pp. 285-298 ◽  
Author(s):  
Eui-Hong Byun ◽  
Woo Sik Kim ◽  
A-Rum Shin ◽  
Jong-Seok Kim ◽  
Jake Whang ◽  
...  

2000 ◽  
Vol 114 (2) ◽  
pp. 295-302 ◽  
Author(s):  
Andrea Cavani ◽  
Francesca Nasorri ◽  
Caterina Prezzi ◽  
Silvia Sebastiani ◽  
Cristina Albanesi ◽  
...  

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