Simultaneous Detection of BCL-2 Protein, Trisomy 12, Retinoblastoma and P53 Monoallelic Gene Deletions in B-Cell Chronic Lymphocytic Leukemia by Fluorescence in Situ Hybridization (FISH): Relation to Disease Status

2000 ◽  
Vol 36 (5-6) ◽  
pp. 503-512 ◽  
Author(s):  
Anna Lazaridou ◽  
Chrysavgi Miraxtsi ◽  
John Korantzis ◽  
Nikos Eleftheriadis ◽  
John I. Christakis
Keyword(s):  
In Situ Hybridization ◽  
Chronic Lymphocytic Leukemia ◽  
B Cell ◽  
Simultaneous Detection ◽  
Disease Status ◽  
Lymphocytic Leukemia ◽  
Gene Deletions ◽  
Trisomy 12 ◽  
Cell Chronic Lymphocytic Leukemia

Clinical, biological, and immunophenotypical characteristics of B-cell chronic lymphocytic leukemia with trisomy 12 by fluorescence in situ hybridization

Cytometry ◽  
1995 ◽  
Vol 22 (3) ◽  
pp. 217-222 ◽  
Author(s):  
Maria Dolores Tabernero ◽  
Jesus F. San Miguel ◽  
Juan Luis Garcia ◽  
Maria Garcia-Isidoro ◽  
Joop Wiegant ◽  
...  
Keyword(s):  
In Situ Hybridization ◽  
Chronic Lymphocytic Leukemia ◽  
B Cell ◽  
Fluorescence In Situ Hybridization ◽  
Lymphocytic Leukemia ◽  
Trisomy 12 ◽  
Cell Chronic Lymphocytic Leukemia

Detection of t(14;18)(q32;q21) in B-Cell Chronic Lymphocytic Leukemia

2005 ◽  
Vol 129 (3) ◽  
pp. 410-411
Author(s):  
Wolfgang Kern ◽  
Torsten Haferlach ◽  
Susanne Schnittger ◽  
Claudia Schoch
Keyword(s):  
Flow Cytometry ◽  
In Situ Hybridization ◽  
Chronic Lymphocytic Leukemia ◽  
Follicular Lymphoma ◽  
B Cell ◽  
Lymphocytic Leukemia ◽  
Multiparameter Flow Cytometry ◽  
Lymphoma Therapy ◽  
Cell Chronic Lymphocytic Leukemia

Abstract Cytomorphologic testing and multiparameter flow cytometry are the mainstays in diagnosing B-cell chronic lymphocytic leukemia, whereas fluorescence in situ hybridization that targets the translocation t(14;18)(q32;q21) often is used to identify follicular lymphoma. Therapy is highly diverse between both diseases. We describe a case with cytomorphologically and immunologically proven B-cell chronic lymphocytic leukemia in which t(14;18)(q32;q21) was found.

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