Chronic relapsing thrombotic thrombocytopenic purpura in pregnancy: A case report

1996 ◽  
Vol 5 (6) ◽  
pp. 328-332
Author(s):  
S. Puza ◽  
M. P. Malee
Author(s):  
Antonios Sfakianakis ◽  
Kalliopi Pappa ◽  
Peter Drakakis ◽  
Georgios Daskalakis ◽  
Dimitrios Loutradis

Author(s):  
ALDO MAINA ◽  
VALENTINA DONVITO ◽  
OSVALDO GIACHINO ◽  
PIERO STRATTA ◽  
CLARA CAMASCHELLA ◽  
...  

2019 ◽  
Vol 152 (6) ◽  
pp. 244-245
Author(s):  
Eva Hernández Lorente ◽  
Rafael Lluch García ◽  
Emilio Monteagudo Santolaya

Author(s):  
M. ATLAS ◽  
G. BARKAI ◽  
J. MENCZER ◽  
N. HOULU ◽  
P. LIEBERMAN

2021 ◽  
pp. 1-5
Author(s):  
Maya Kornowski Cohen ◽  
Liron Sheena ◽  
Yair Shafir ◽  
Vered Yahalom ◽  
Anat Gafter-Gvili ◽  
...  

SARS-CoV-2 has been reported as a possible triggering factor for the development of several autoimmune diseases and inflammatory dysregulation. Here, we present a case report of a woman with a history of systemic lupus erythematosus and antiphospholipid syndrome, presenting with concurrent COVID-19 infection and immune thrombotic thrombocytopenic purpura (TTP). The patient was treated with plasma exchange, steroids, and caplacizumab with initial good response to therapy. The course of both TTP and COVID-19 disease was mild. However, after ADAMTS-13 activity was normalized, the patient experienced an early unexpected TTP relapse manifested by intravascular hemolysis with stable platelet counts requiring further treatment. Only 3 cases of COVID-19 associated TTP were reported in the literature thus far. We summarize the literature and suggest that COVID-19 could act as a trigger for TTP, with good outcomes if recognized and treated early.


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