Thrombotic thrombocytopenic purpura in pregnancy

Author(s):  
M. ATLAS ◽  
G. BARKAI ◽  
J. MENCZER ◽  
N. HOULU ◽  
P. LIEBERMAN
Blood ◽  
2020 ◽  
Vol 136 (19) ◽  
pp. 2125-2132
Author(s):  
Barbara Ferrari ◽  
Flora Peyvandi

Abstract Thrombotic thrombocytopenic purpura (TTP) is an acute, life-threatening thrombotic microangiopathy (TMA) caused by acquired or congenital severe deficiency of ADAMTS13. Pregnancy is a recognized risk factor for precipitating acute (first or recurrent) episodes of TTP. Differential diagnosis with other TMAs is particularly difficult when the first TTP event occurs during pregnancy; a high index of suspicion and prompt recognition of TTP are essential for achieving a good maternal and fetal outcome. An accurate distinction between congenital and acquired cases of pregnancy-related TTP is mandatory for safe subsequent pregnancy planning. In this article, we summarize the current knowledge on pregnancy-associated TTP and describe how we manage TTP during pregnancy in our clinical practice.


1981 ◽  
Vol 141 (1) ◽  
pp. 20-24 ◽  
Author(s):  
Siva Thiagarajah ◽  
Guy M. Harbert ◽  
Michael R. Caudle ◽  
Benjamin C. Sturgill

Author(s):  
Ebellins Tabares Calvache ◽  
Júlia Plentz Portich ◽  
Tayse Yone Barbeta ◽  
Cristiane Seganfredo Weber

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