FHL1 is differentially expressed in non-small cell lung cancer and associates with patient survival.

Small Cell Lung ◽

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that FHL1 was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. FHL1 expression was significantly decreased in NSCLC tumors as compared to the lung, and lower expression of FHL1 in patient tumors was significantly associated with worse overall survival. FHL1 may be important for initiation or progression of non-small cell lung cancer in humans.

The roundabout guidance receptor 4, ROBO4, is differentially expressed in non-small cell lung cancer and associates with patient survival.

10.31219/osf.io/5kzsq ◽

2020 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Microarray Data ◽

Patient Survival ◽

The United States ◽

Small Cell ◽

Small Cell Lung ◽

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that ROBO4 was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. ROBO4 expression was significantly decreased in NSCLC tumors as compared to the lung, and lower expression of ROBO4 in patient tumors was significantly associated with worse overall survival. ROBO4 may be important for initiation or progression of non-small cell lung cancer in humans.

ADH1B is differentially expressed in non-small cell lung cancer and associates with patient survival.

10.31219/osf.io/eunh3 ◽

2020 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Microarray Data ◽

Patient Survival ◽

The United States ◽

Small Cell ◽

Small Cell Lung ◽

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that ADH1B was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. ADH1B expression was significantly decreased in NSCLC tumors as compared to the lung, and lower expression of ADH1B in patient tumors was significantly associated with worse overall survival. ADH1B may be important for initiation or progression of non-small cell lung cancer in humans.

EMP2 is differentially expressed in non-small cell lung cancer and associates with patient survival.

10.31219/osf.io/u4dqa ◽

2020 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Microarray Data ◽

Patient Survival ◽

The United States ◽

Small Cell ◽

Small Cell Lung ◽

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that EMP2 (5) was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. EMP2 expression was significantly decreased in NSCLC tumors as compared to the lung, and lower expression of EMP2 in patient tumors was significantly associated with worse overall survival. EMP2 may be important for initiation or progression of non-small cell lung cancer in humans.

FXYD6 is differentially expressed in non-small cell lung cancer and associates with patient survival.

10.31219/osf.io/v7kps ◽

2020 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Microarray Data ◽

Patient Survival ◽

The United States ◽

Small Cell ◽

Small Cell Lung ◽

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that FXYD6 was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. FXYD6 expression was significantly decreased in NSCLC tumors as compared to the lung, and lower expression of FXYD6 in patient tumors was significantly associated with worse overall survival. FXYD6 may be important for initiation or progression of non-small cell lung cancer in humans.

Aspartoacyclase is differentially expressed in non-small cell lung cancer and associates with patient survival.

10.31219/osf.io/dkf8p ◽

2020 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Patient Survival ◽

The United States ◽

Small Cell ◽

Small Cell Lung ◽

Gene Encoding ◽

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4, 5) to identify differentially expressed genes in NSCLC. We found that the gene encoding aspartoacyclase (ASPA) was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. ASPA expression was significantly decreased in NSCLC tumors as compared to the lung, and lower expression of ASPA in patient tumors was significantly associated with worse overall survival. ASPA may be important for initiation or progression of non-small cell lung cancer in humans.

The natriuretic peptide receptor, NPR1 is differentially expressed in non-small cell lung cancer and associates with patient survival.

10.31219/osf.io/ekhuc ◽

2020 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Patient Survival ◽

The United States ◽

Small Cell ◽

Small Cell Lung ◽

Peptide Receptor ◽

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that NPR1 was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. NPR1 expression was significantly decreased in NSCLC tumors as compared to the lung, and lower expression of NPR1 in patient tumors was significantly associated with worse overall survival. NPR1 may be important for initiation or progression of non-small cell lung cancer in humans.

The gene encoding tensin 1, TNS1, is differentially expressed in non-small cell lung cancer and associates with patient survival.

10.31219/osf.io/mc687 ◽

2020 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Patient Survival ◽

The United States ◽

Small Cell ◽

Small Cell Lung ◽

Gene Encoding ◽

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that tensin 1, encoded by TNS1, was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. TNS1 expression was significantly decreased in NSCLC tumors as compared to the lung, and lower expression of TNS1 in patient tumors was significantly associated with worse overall survival. TNS1 may be important for initiation or progression of non-small cell lung cancer in humans.

The type III TGF beta receptor is differentially expressed in non-small cell lung cancer and associates with patient survival.

10.31219/osf.io/73nrf ◽

2020 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

Transforming Growth Factor ◽

Patient Survival ◽

The United States ◽

Small Cell ◽

Small Cell Lung ◽

Type Iii

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding the type III transforming growth factor (TGF)-β receptor, TGFBR3, was among the genes whose expression was most quantitatively different in tumors from patients with NSCLC as compared to the lung. TGFBR3 expression was significantly decreased in NSCLC tumors as compared to the lung, and lower expression of TGFBR3 in patient tumors was significantly associated with worse overall survival. We previously reported differential and decreased expression of LTBP4 (5) which associated with patient survival in NSCLC. TGFBR3, and the TGF-β signaling pathway may be important for initiation or progression of non-small cell lung cancer in humans.

Glycoprotein M6A is differentially expressed in non-small cell lung cancer and associates with patient survival.

10.31219/osf.io/fnskw ◽

2020 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

The United States ◽

Small Cell ◽

Small Cell Lung ◽

Gene Encoding ◽

Human Nsclc ◽

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that gene encoding glycoprotein M6A, GPM6A, was among those whose expression was most quantitatively different in human NSCLC tumors as compared to the lung. GPM6A expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of GPM6A in patient tumors was significantly associated with worse overall survival. GPM6A may be important for initiation or progression of non-small cell lung cancer in humans.

RhoJ is differentially expressed in non-small cell lung cancer and associates with patient survival.

10.31219/osf.io/uynp7 ◽

2020 ◽

Author(s):

Shahan Mamoor

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Cell Lung Cancer ◽

The United States ◽

Small Cell ◽

Small Cell Lung ◽

Gene Encoding ◽

Human Nsclc ◽

Non-small cell lung cancer (NSCLC) is the leading cause of cancer death in the United States (1). We mined published microarray data (2, 3, 4) to identify differentially expressed genes in NSCLC. We found that the gene encoding RhoJ, the ras homolog family member J (RhoJ) among those whose expression was most quantitatively different in human NSCLC tumors as compared to the lung. RhoJ expression levels were significantly decreased in NSCLC tumors as compared to the lung, and lower expression of RhoJ in patient tumors was significantly associated with worse overall survival. RhoJ may be important for initiation or progression of non-small cell lung cancer in humans.