scholarly journals Ethical challenges in Research, Industry and People Partnerships in mental health

Author(s):  
Sapfo Lignou ◽  
John Geddes ◽  
Ilina Singh

Advancements in mental health research, social changes and policy developments have led to the emergence of new forms of research partnerships, which bring together research institutions, public companies and lay people as partners in the same research project. In this paper, we argue that partnerships comprised of industry, academia and people with experience of mental illness may present practical and ethical challenges that affect the conduct of research and undermine public trust in research collaborations. We outline a number of ethical problems from the motivation to combine competing interests and values of these diverse research partners. We argue that while critical perspectives on each of the partnership forms outlined above exist in the literature, the combination of industry, research and PPI actors in partnership in mental health research has not received sufficient scrutiny. We suggest that a robust ethical approach is needed to properly substantiate the value of such research partnerships, to inform practical and ethical guidance on potential conflicts and to facilitate productive collaborative research.

2011 ◽  
Vol 2 (4) ◽  
pp. 42-51 ◽  
Author(s):  
Gloria D. Eldridge ◽  
Mark E. Johnson ◽  
Christiane Brems ◽  
Staci L. Corey

2020 ◽  
Vol 5 ◽  
pp. 196
Author(s):  
Sapfo Lignou ◽  
Ilina Singh

Background: Several social and policy developments have led to research partnerships in mental health research, which depart from traditional research models. One form of such partnerships is among research institutions, industry (pharmaceutical and biotech) and people with lived experience of mental illness (RIPs). There are several benefits but also ethical challenges in RIPs. An ethics-based approach to anticipating and addressing such ethical issues in mental health research is lacking. Given the expansion of RIPs in treatment development for mental health illness, guidance to support ethical and trustworthy collaborative mental health research projects is essential. Methods: To develop a moral framework for evaluating the ethics of RIPs, we systematically searched PubMed for peer-reviewed literature discussing good practices in research partnerships. Searches were also conducted in websites of known organizations supporting patient engagement with industry in mental health research and in the references of short-listed articles. Following application of exclusion criteria, remaining articles were critically examined and summarised to synthesise principles for ethically acceptable RIPs and inform clear guidance and practices. Results: Critical analysis and synthesis of the short-listed articles highlighted the need for two sets of principles to guide ethical RIPs: principles for (a) RIPs as a trustworthy enterprise (e.g. public accountability, transparency) and (b) fair RIPs (e.g. effective governance, respect). We discuss the application of these principles in problem-solving strategies that can support best practice in establishing fair and successful mental health research partnerships among research institutions, industry and people with lived experience of mental illness. Conclusions: Ethical guidance is needed to prevent and address challenges in RIPs and to promote the scientific and social benefits of these new research partnership models in mental health research. We show how the proposed moral framework can guide research partners in designing, sustaining and assessing ethical and trustworthy collaborative mental health research projects.


2015 ◽  
Vol 16 (1) ◽  
pp. 15-28 ◽  
Author(s):  
Anna Chiumento ◽  
Muhammad Naseem Khan ◽  
Atif Rahman ◽  
Lucy Frith

2021 ◽  
Vol 5 ◽  
pp. 196
Author(s):  
Sapfo Lignou ◽  
Ilina Singh

Background: Several social and policy developments have led to research partnerships in mental health research, which depart from traditional research models. One form of such partnerships is among Research institutions, Industry (pharmaceutical and biotech) and People with lived experience of mental illness (RIPs) in the NIHR services. There are several benefits but also challenges in such partnerships. An ethics-based approach to anticipating and addressing such problems is lacking. Given the expansion of RIPs in treatment development for mental health illness, guidance to support ethical and effective collaborations in NIHR-funded mental health research is essential. Methods: To develop a moral framework for evaluating the ethics of RIPs, we systematically searched PubMed for peer-reviewed literature discussing good practices in research partnerships. Searches were also conducted in websites of known organizations supporting patient engagement with industry in mental health research and in the references of short-listed articles. Following application of exclusion criteria, remaining articles were critically examined and summarised to synthesise principles for ethical RIPs and inform clear guidance and practices. Results: Critical analysis and synthesis of the short-listed articles highlighted the need for two sets of principles to guide ethical RIPs: principles for (a) RIPs as a trustworthy enterprise and (b) fair RIPs. We discuss the application of these principles in problem-solving strategies that can support best practice in establishing fair and effective research partnerships among research institutions, industry and people with lived experience of mental illness in the NIHR services. Conclusions: Ethical guidance is needed to prevent and address challenges in RIPs and to promote the scientific and social benefits of these new research partnership models in mental health research in the NIHR services. We show how the proposed moral framework can guide research partners in designing, sustaining and assessing ethical and effective mental health research collaborations.


2000 ◽  
Vol 26 (1) ◽  
pp. 7-12 ◽  
Author(s):  
Cheryl A. Boyce ◽  
Kimberly Hoagwood ◽  
Michael L. Lopez ◽  
Louisa B. Tarullo

2018 ◽  
Vol 17 (1) ◽  
pp. 8-11
Author(s):  
Pratik Khanal ◽  
Sajana Maharjan

People with mental health problems are considered as vulnerable population by national ethical guidelines of health research in Nepal. There are different ethical challenges in research involving people with mental health problems. Ethical challenges are related to study design, autonomy, beneficence and nonmaleficence, justice, respect for the environment and consent taking process. Respecting the human rights of those with mental health problems is necessary during research and this requires research stakeholders to be responsible.


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