Early Experiences with Management of Extra Hepatic Portal Vein Obstruction

Introduction: Extrahepatic portal vein obstruction (EHPVO), a rare condition, is increasingly being diagnosed due to easier availability of proper diagnostic tools and early referrals. Here we report our series of 16 cases of EHPVO who were treated at our hospital. The aim of this paper is to share our early experiences of managing this rare and difficult condition. Methods: A retrospective analysis of patients’ records admitted with the diagnosis of EHPVO for a period of 18 months from Jan 2008 to June 2010 was performed. Patients were followed up for at least 9 months, their demographic data and outcome of surgery was analysed. Results: Of the 10 cases fulfilling the inclusion criteria, 9 underwent surgical therapy. Distal lienorenal shunt was performed in 4 patients, proximal lienorenal shunt in 2 patients and devascularisation procedure in 3 patients. Rebleeding was seen in 2 patients. The prognosis of EHPVO was good in patients without a severe underlying disease at a median follow up of 9 months. Conclusion: Conventional surgical therapies have a good outcome in management of EHPVO in our context. Medical Journal of Shree Birendra Hospital; July-December 2012/vol.11/Issue2/4-6 DOI: http://dx.doi.org/10.3126/mjsbh.v11i2.7898

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Extra-hepatic portal vein obstruction (EHPVO) in adult patients: Role of congenital or acquired thrombophylic disorders as etiologic factors

Journal of Hepatology ◽

10.1016/s0168-8278(00)80857-0 ◽

2000 ◽

Vol 32 ◽

pp. 137

Author(s):

M. Primignani ◽

N. De Bortoli ◽

M. Moia ◽

P. Bucciarelli ◽

P. Preatoni ◽

...

Keyword(s):

Portal Vein ◽

Adult Patients ◽

Portal Vein Obstruction ◽

Hepatic Portal Vein ◽

Hepatic Portal

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Death of a 3 Month-Old Infected Infant with Dilated Cardiomyopathy after COVID-19 Infection: A Case Report

World Journal of Peri & Neonatology ◽

10.18502/wjpn.v4i1.7546 ◽

2021 ◽

Author(s):

Fatemeh Baghalsafa ◽

Hossein Neamatzadeh ◽

Sedigheh Ekraminasab

Keyword(s):

Case Report ◽

Dilated Cardiomyopathy ◽

Cardiac Injury ◽

Viral Myocarditis ◽

Rare Condition ◽

Underlying Disease ◽

Pediatric Emergency ◽

Sufficient Evidence ◽

Infected Infant ◽

Severe Underlying Disease

Background: Several numbers of studies have reported that coronavirus disease-2019 (COVID-19) in infants and children have shown milder symptoms and a better prognosis than in adult patients. However, there is no sufficient evidence on the effect of cardiovascular involvement in COVID-19 in the infant. Case Report: Here, we report an infant infected with COVID-19 with the manifestations of dilated myocarditis. The patient was referred to Pediatric Emergency with lethargy and tachypnea. On physical examination, she had holosystolic murmur with grade 3/6. The laboratory examinations showed anemia as well as increased alkaline phosphatase (ALP) levels. Due to respiratory distress, she was intubated and put under mechanical ventilation. The diagnosis of COVID-19 infection was confirmed by real-time polymerase chain reaction (RT-PCR) using a pharyngeal specimen. Finally, dilated cardiomyopathy (DCM) was diagnosed and one day after hospitalization the infant was died due to complications of DCM. Conclusion: It seems that in the infant with severe underlying disease, even a mild COVID-19 infection, may be lethal. Focal viral myocarditis is a very rare condition described by localized disturbance of the myocardium occurring in ventricular dysfunction with significant morbidity and mortality. Thus, due to the possibility of cardiac injury in infected neonates with COVID-19 disease and the manifestation of myocarditis, effective measurement is recommended.

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