scholarly journals A Case of Acute Hepatitis E Complicated by Acute Pancreatitis in Eastern India

2020 ◽  
Vol 12 (2) ◽  
Author(s):  
Rudrajit P ◽  
Shubhabrata D ◽  
Sourav P ◽  
Partha SC ◽  
Jayati M ◽  
...  

Viral hepatitis may be occasionally associated with acute pancreatitis. Usually the patient presents with abdominal pain in the second or third week of illness. Hepatitis A or E viruses are mostly implicated. HEV related acute pancreatitis was first reported only 12 years ago. We report a case of a young male presenting with acute Hepatitis E infection complicated by pancreatitis. He had an uneventful recovery. This is probably the first report of this association from Eastern India.

2013 ◽  
Vol 2013 ◽  
pp. 1-3 ◽  
Author(s):  
Hemanta Kumar Nayak ◽  
Nitish L. Kamble ◽  
Nishant Raizada ◽  
Sandeep Garg ◽  
Mradul Kumar Daga

Acute pancreatitis complicating fulminant viral hepatitis has been well recognized; however, acute pancreatitis occurring in nonfulminant hepatitis is very rare. The case presented describes moderate pancreatitis in a young male, manifesting during the course of nonfulminant acute hepatitis E infection. The diagnosis of acute viral hepatitis E was confirmed by serology and reverse transcriptase polymerase chain reaction (RT-PCR) to demonstrate Hepatitis E virus (HEV) RNA in both stool and serum. Patients with acute viral hepatitis presenting with severe abdominal pain should have a diagnosis of acute pancreatitis suspected and appropriate investigations including serum amylase, lipase, biliary ultrasonography and/or contrast-enhanced computed tomography of the abdomen should be undertaken. The identification of this unusual complication of Hepatitis E is important; however, the prognosis for patients with Acute Pancreatitis Complicating Acute Hepatitis E Virus Infection is good, and uncomplicated recovery with conservative treatment is expected.


2011 ◽  
Vol 51 (181) ◽  
Author(s):  
S K.C. ◽  
S Khadka ◽  
D Sharma ◽  
SP Chataut

Introduction: The association of acute viral hepatitis and acute pancreatitis is well described. This study was conducted to find out the frequency of pancreatic involvement in acute viral hepatitis in the Nepalese population. Methods: Consecutive patients of acute viral hepatitis presenting with severe abdominal pain between January 2005 and April 2010 were studied. Patients with history of significant alcohol consumption and gall stones were excluded. Acute viral hepatitis was diagnosed by clinical examination, liver function test, ultrasound examination and confirmed by viral serology. Pancreatitis was diagnosed by clinical presentation, biochemistry, ultrasound examination and CT scan. Results: Severe abdominal pain was present in 38 of 382 serologically-confirmed acute viral hepatitis patients. Twenty five patients were diagnosed to have acute pancreatitis. The pancreatitis was mild in 14 and severe in 11 patients. The etiology of pancreatitis was hepatitis E virus in 18 and hepatitis A virus in 7 patients. Two patients died of complications secondary to shock. The remaining patients recovered from both pancreatitis and hepatitis on conservative treatment. Conclusions: Acute pancreatitis occurred in 6.5 % of patients with acute viral hepatitis. Cholelithiasis and gastric ulcers are the other causes of severe abdominal pain. The majority of the patients recover with conservative management. Keywords: acute viral hepatitis, acute pancreatitis, pain abdomen, hepatitis E, hepatitis A, endemic zone  


Pathogens ◽  
2021 ◽  
Vol 10 (1) ◽  
pp. 60
Author(s):  
Thomas Theo Brehm ◽  
Omid Mazaheri ◽  
Thomas Horvatits ◽  
Marc Lütgehetmann ◽  
Julian Schulze zur Wiesch ◽  
...  

In patients with hepatitis E virus (HEV) infections, extrahepatic, particularly renal and hematological manifestations, are increasingly reported in the medical literature but have never been studied compared to a control cohort. We retrospectively analyzed medical records of consecutive patients that were diagnosed with acute hepatitis E (AHE) (n = 69) or acute hepatitis A (AHA) (n = 46) at the University Medical Center Hamburg Eppendorf from January 2009 to August 2019 for demographical, clinical, and laboratory information. Patients with AHE had significantly lower median levels of ALAT (798 U/L) and total bilirubin (1.8 mg/dL) compared to patients with AHA (2326 U/L; p < 0.001 and 5.2 mg/dL; p < 0.001), suggesting a generally less severe hepatitis. In contrast, patients with AHE had significantly higher median serum creatinine levels (0.9 mg/dL vs. 0.8 mg/dL; p = 0.002) and lower median estimated glomerular filtration rate (eGFR) (91 mL/min/1.73 m2 vs. 109 mL/min/1.73 m2; p < 0.001) than patients with AHA. Leucocyte, neutrophil and lymphocyte count, hemoglobin, platelets, red cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR), and RDW to lymphocyte ratio (RLR) did not differ between patients with AHE and those with AHA. Our observations indicate that renal but not hematological interference presents an underrecognized extrahepatic feature of AHE, while inflammation of the liver seems to be more severe in AHA.


2011 ◽  
Vol 51 (3) ◽  
pp. 202-204 ◽  
Author(s):  
Cécile Deniel ◽  
Thierry Coton ◽  
Sarah Brardjanian ◽  
Michel Guisset ◽  
Elisabeth Nicand ◽  
...  

2015 ◽  
Vol 62 ◽  
pp. S553-S554
Author(s):  
K.L. Woolson ◽  
A. Forbes ◽  
R.G. Madden ◽  
P. Oppong ◽  
J.G. Hunter ◽  
...  

2009 ◽  
Vol 59 (6) ◽  
pp. S447-S448
Author(s):  
Catherine Cosgrove ◽  
Michael Brown ◽  
Margaret Armstrong ◽  
Justin Doherty

2009 ◽  
Vol 51 (6) ◽  
pp. 349-351 ◽  
Author(s):  
Danilo Bora Moleta ◽  
Fábio Toshio Kakitani ◽  
Adma Silva de Lima ◽  
João César Beenke França ◽  
Sonia Mara Raboni

This case report, along with the review presented, describes a patient diagnosed with acute viral hepatitis, who developed a framework of intense abdominal pain and laboratorial alterations compatible with acute pancreatitis. The association of acute pancreatitis complicating fulminant and non-fulminant acute hepatitis virus (AHV) has been reported and several mechanisms have been proposed for this complication, but so far none is clearly involved. As acute hepatitis is a common disease, it is important to stimulate the development of other studies in order to determine local incidence and profile of patients presenting this association in our environment.


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