Orphan designation: Sodium benzoate,Sodium phenylacetate, Treatment of hyperargininaemia

2019 ◽  
Author(s):  
2000 ◽  
Vol 23 (2) ◽  
pp. 129-136 ◽  
Author(s):  
V. Praphanproj ◽  
S. A. Boyadjiev ◽  
L. J. Waber ◽  
S. W. Brusilow ◽  
M. T. Geraghty

1988 ◽  
Vol 23 (4) ◽  
pp. 368-374 ◽  
Author(s):  
Mark L Batshaw ◽  
Susan L Hyman ◽  
Joseph T Coyle ◽  
Michael B Robinson ◽  
Ijaz A Qureshi ◽  
...  

1972 ◽  
Vol 27 (5) ◽  
pp. 528-530 ◽  
Author(s):  
Helga Wittmann ◽  
Helmut Rathmayr

Benzylmalonyl Chloride reacts in the presence of sodium acetate in boiling benzene to give tribenzyl-phloroglucinol-triacetate, however with sodium chloroacetate to 3,5-dibenzyl-6-phenethylpyran-2,4-dion. In both cases trimerisation of benzylketene or benzylketene carboxylic acid chloride occurs. On the other hand, benzylmalonylchloride reacts with sodium benzoate and sodium phenylacetate via a dimeric benzylketene carboxylic acid chloride under the loss of phosgene to yield cyclopentadienyl derivatives.


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