Über die Umsetzung von Benzylmalonylchlorid mit verschiedenen Natriumsalzen von Carbonsäuren / The Reaction of Benzylmalonyl Chloride with Sodium Salts of Carboxylic Acids

1972 ◽  
Vol 27 (5) ◽  
pp. 528-530 ◽  
Author(s):  
Helga Wittmann ◽  
Helmut Rathmayr
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Acid Chloride ◽  
Sodium Benzoate ◽  
Sodium Acetate ◽  
The Other ◽  
Carboxylic Acid Chloride ◽  
Sodium Salts ◽  
Other Hand ◽  
Sodium Phenylacetate

Benzylmalonyl Chloride reacts in the presence of sodium acetate in boiling benzene to give tribenzyl-phloroglucinol-triacetate, however with sodium chloroacetate to 3,5-dibenzyl-6-phenethylpyran-2,4-dion. In both cases trimerisation of benzylketene or benzylketene carboxylic acid chloride occurs. On the other hand, benzylmalonylchloride reacts with sodium benzoate and sodium phenylacetate via a dimeric benzylketene carboxylic acid chloride under the loss of phosgene to yield cyclopentadienyl derivatives.

Preparation and reactions of thieno[3,2-b]furan derivatives

1986 ◽  
Vol 51 (8) ◽  
pp. 1685-1691 ◽  
Author(s):  
Eva Kraľovičová ◽  
Alžbeta Krutošíková ◽  
Jaroslav Kováč
Keyword(s):  
Carboxylic Acid ◽  
Carboxylic Acids ◽  
Acid Chloride ◽  
Thionyl Chloride ◽  
Acid Chlorides ◽  
Carboxylic Acid Chloride ◽  
Furan Derivatives ◽  
Nucleophilic Reactions ◽  
Triethylbenzylammonium Chloride

Reactions of 3-(5-aryl-2-furyl)propenoic, 3-(2-benzo[b]furyl)propenoic and 3-(5-ethoxycarbonyl-4H-furo[3,2-b]-2-pyrrolyl)propenoic acids with thionyl chloride in the presence of triethylbenzylammonium chloride were investigated. The obtained 2-arylthieno[3,2-b]-furan-5-carboxylic acid chlorides Ia - Ic and 3-chlorothieno[3,2-b]benzo[b]furan-2-carboxylic acid chloride afforded in substitution nucleophilic reactions the corresponding esters V and carboxylic acids VI which were decarboxylated to VII. 3-Chlorothieno[3,2-b]benzo[b]furan-2-carboxylic acid chloride (Id), 6-ethoxycarbonyl-3-chlorothieno[2',3':4,5]furo[3,2-b]pyrrole-2-carboxylic acid chloride (IV), and ethyl 3-chlorothieno[2',3':4,5]furo[3,2-b]indole-2-carboxylate (VIII), synthesized under conditions of triethylphosphite reduction from ethyl 6-chloro-2-(2-nitrophenyl)thieno[3,2-b]furan-5-carboxylate (Va), are new heterocyclic systems.

scholarly journals EFFECT OF COCAINE ON THE GROWTH OF LUPINUS ALBUS. A CONTRIBUTION TO THE COMPARATIVE PHARMACOLOGY OF ANIMAL AND PLANT PROTOPLASM

1922 ◽  
Vol 4 (5) ◽  
pp. 573-584 ◽  
Author(s):  
David I. Macht ◽  
Marguerite B. Livingston
Keyword(s):  
Sodium Benzoate ◽  
Lupinus Albus ◽  
The Other ◽  
Plant Roots ◽  
Animal Tissues ◽  
Decomposition Products ◽  
Other Hand ◽  
Low Toxicity

1. The effects of cocaine and its decomposition products were studied on the growth of the young roots of Lupinus albus. 2. The results obtained were compared with similar experiments on animal tissues. 3. It was found that, while cocaine is the most toxic of these compounds studied for animal tissues, it was of comparatively low toxicity in respect to its effect on the growth of roots. On the other hand, sodium benzoate, being practically non-toxic for animals, was the most toxic of the compounds studied for the plant roots.

Synthesis of amino acid diazoketones

1986 ◽  
Vol 64 (11) ◽  
pp. 2097-2102 ◽  
Author(s):  
George R. Pettit ◽  
Paul S. Nelson
Keyword(s):  
Amino Acid ◽  
Carboxylic Acid ◽  
Acid Chloride ◽  
Low Temperatures ◽  
Oxalyl Chloride ◽  
Acyl Chloride ◽  
Carboxyl Group ◽  
Carboxylic Acid Chloride ◽  
Active Esters ◽  
Active Ester

A study of carboxylic acid → diazoketone conversion was pursued employing the γ-carboxyl group of otherwise protected L-glutamic acids. The Arndt–Eistert route employing carboxylic acid chloride intermediates was found best (52% yield, 5b), performed at very low temperatures employing oxalyl chloride in dimethylformamide–tetrahydrofuran followed by diazomethane at −23 °C. Alternatively, substitution of a mixed carbonic anhydride for the acyl chloride led to very similar yields (57% of 5b) of diazoketones (5). Among a series of active ester intermediates (7) examined, only the ODnp (7d) and SPfp (7f) esters were found to react (23–26% yield), at least partially, with diazomethane. The latter two reactions appear to represent the first such examples employing active esters.

scholarly journals Spectroscopy Study of Honey Pineapple Peels Extracted in Different Solvents

2021 ◽  
Vol 3 (1) ◽  
pp. 32-35
Author(s):  
Yehezkiel Steven Kurniawan ◽  
Edi Setiyono ◽  
Marcelinus Alfasisurya Setya Adhiwibawa ◽  
Krisfian Tata Aneka Priyangga ◽  
Leny Yuliati
Keyword(s):  
Carboxylic Acid ◽  
Visible Region ◽  
Water Extract ◽  
Ethanolic Extract ◽  
Acetone Extract ◽  
The Other ◽  
Distilled Water ◽  
Spectroscopy Study ◽  
Absorption Signal ◽  
Other Hand

In the present work, we investigated the extract of honey pineapple peels in distilled water, ethanol, and acetone solvents. The spectroscopy study of each extract was performed using a Fourier transform infrared (FTIR) spectrometer, an ultraviolet-visible (UV-Vis) spectrophotometer, and a spectrofluorometer. The FTIR spectrum of the distilled water extract indicated that the distilled water extract may contain alcohol or carboxylic acid compounds. Meanwhile, the ethanolic extract may contain alcohol or carboxylic acid, or ether compounds. On the other hand, the acetone extract may contain alcohol or ether or aromatic or aliphatic compounds. The UV-Vis spectrum of the honey pineapple peels extracted in the distilled water, ethanol, and acetone showed a broad absorption signal at UV region (< 300 nm), four absorption signals at UV region (232-368 nm), and four absorption signals at UV region (231-368 nm) with a weak absorption signal at the visible region at 559 nm, respectively. The distilled water and acetone extracts gave fluorescence signals, however, the ethanolic extract showed no fluorescence intensity. From the FTIR, UV-Vis, and fluorescence spectra characterization, the extracted natural pigments from the honey pineapple peels in distilled water, ethanol, and acetone solvents were identified. The distilled water extract may contain polar flavonoid or steroid compounds while the ethanolic extract may contain polar carotenoid pigments. On the other hand, the acetone extract may contain carotenoid and chlorophyll pigments as shown by an emission signal at 670 nm.

Synthesis and Reactions of Some 1H-Pyrazole-3 Carboxylic Acid Chloride

2009 ◽  
Vol 15 (4) ◽  
Author(s):  
İhan Özer İlhan ◽  
Sevgi Zühal ◽  
Zülbiye Önal ◽  
Emin Saripinar
Keyword(s):  
Carboxylic Acid ◽  
Acid Chloride ◽  
Carboxylic Acid Chloride

THE REACTION OF CYANOGEN BROMIDE WITH THE SODIUM SALTS OF CARBOXYLIC ACIDS: I. THE REACTION OF CYANOGEN BROMIDE WITH SODIUM BENZOATE

1953 ◽  
Vol 31 (11) ◽  
pp. 1127-1130 ◽  
Author(s):  
D. E. Douglas ◽  
Jean Eccles ◽  
Anne E. Almond
Keyword(s):  
Carbon Dioxide ◽  
Carboxylic Acids ◽  
Sodium Benzoate ◽  
Cyanogen Bromide ◽  
Sodium Bromide ◽  
Tracer Studies ◽  
Sodium Salts

The main products of the reaction of cyanogen bromide with sodium benzoate at 250 ° to 300 °C. are carbon dioxide, benzonitrile, and sodium bromide. Tracer studies have shown that the carbon of the carbon dioxide is derived almost entirely from the cyanogen bromide.

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