Effective Use of PEC I and PEC II Blocks for Subcutaneous Cardiac Pacemaker Insertion: A Case Series

The purpose of this study was to investigate, over a period of five years, the cortical maturation of the central auditory pathways and its impacts on the auditory and oral language development of children with effective use and without effective use of a Cochlear Implant (CI). A case series study was conducted with seven children who were CI users and seven children with normal hearing, with age- and gender-matched to CI users. The assessment was performed by long-latency auditory evoked potentials and auditory and oral language behavioral protocols. The results pronounced P1 latency decrease in all CI users in the first nine months. Over five years, five children with effective CI use presented decrease or stabilization of P1 latency and a gradual development of auditory and oral language skills, although, for most of the children, the electrophysiological and behavior results remained poor than their hearing peers’ results. Two children who stopped the effective use of CI after the first year of activation had worsened auditory and oral language behavioral skills and presented increased P1 latency. A negative correlation was observed between behavioral measures and the P1 latency, the P1 component being considered an important clinical resource capable of measuring the cortical maturation and the behavioral evolution.

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Implanted Cardiac Pacemaker Mathematical Modeling and Research Based on the Volume Conduction

Biotechnology ◽

10.4018/978-1-5225-8903-7.ch036 ◽

2019 ◽

pp. 923-939

Author(s):

Lixiao Feng ◽

Junjie Bai ◽

Chengyuan Chen ◽

Jun Peng ◽

Guorong Chen

Keyword(s):

Channel Capacity ◽

Human Body ◽

Cardiac Pacemaker ◽

Volume Conduction ◽

Eye Diagram ◽

Channel Simulation ◽

Low Snr ◽

Awgn Channel ◽

Multi Level ◽

Effective Use

The research of the communication between implanted Cardiac Pacemaker and external devices is a focus. In this paper, a data communications model based Volume Conduction is creatively presented, in this way the human body conductive ability will been utilized to transmit current, which is more effective and decrease for harm of the human body than the other ways, such as: RF, Optical Transcutaneous, etc. As the frequency increases the KHz level, the effect of background biological noise is considered negligible, the channel is thus modeled as AWGN channel in these frequencies. From Shannon information theory, in two-dimensional modulation, the volume conduction channel capacity formula was derived, further derivation: with extremely low SNR using in the two-level modulation can be very effective use of channel capacity, with high SNR a multi-level modulation is used in order to make full use of the channel capacity. Matlab software is used to the channel simulation, the input and output signal waveforms and eye diagram comparison, the curves of the BER and SNR.

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The Use of Topical Tacrolimus 0.1% Skin Ointment for Anterior Segment Conditions: A Case Series

Ophthalmology and Eye Diseases ◽

10.1177/117917211000200001 ◽

2010 ◽

Vol 2 ◽

pp. 117917211000200 ◽

Cited By ~ 2

Author(s):

Poorna Abeysiri ◽

Nicholas R. Johnston ◽

Anthony C.B. Molteno

Keyword(s):

Graft Rejection ◽

Anterior Segment ◽

Case Series ◽

Operative Management ◽

Vernal Keratoconjunctivitis ◽

Fk 506 ◽

Topical Tacrolimus ◽

Inflammatory Conditions ◽

License Application ◽

Effective Use

Tacrolimus (FK 506) is a macrolactam derivative with immunomodulatory and anti-inflammatory activity. Topical tacrolimus 0.03% has been used for inflammatory conditions of the anterior segment. This article adds to the literature on the off-license application of tacrolimus ointment, by describing the safe and effective use of the higher strength of 0.1% topical tacrolimus skin ointment in four patients. To our knowledge this is the first report of topical tacrolimus 0.1% ointment applied to the conjunctival sac for the treatment of atopic keratoconjunctivitis, vernal keratoconjunctivitis and the post-operative management of trabeculectomy and graft rejection in steroid responders.

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