RCT Investigating Pre-operative Vaginal Wash of Chlorhexidine vs Povidone-iodine and Reducing Infectious Morbidity After Cesarean Section With Ruptured Membranes

2019 ◽  
Author(s):  
Keyword(s):  
Cesarean Section ◽  
Povidone Iodine ◽  
Infectious Morbidity ◽  
Vaginal Wash

scholarly journals Vaginal preparation with povidone iodine solution before caesarean section and its impact on the post-operative infectious morbidity

2021 ◽  
Vol 10 (7) ◽  
pp. 2775
Author(s):  
Savita Chandra ◽  
Vandana Singh
Keyword(s):  
Povidone Iodine ◽  
Statistical Significance ◽  
Control Group ◽  
P Value ◽  
Iodine Solution ◽  
Postoperative Fever ◽  
Infectious Morbidity ◽  
Group A ◽  
Vaginal Wash ◽  
Povidone Iodine Solution

Background: A prospective randomized control trial (RCT) was conducted in the department of obstetrics and gynecology. The aim of the study was to evaluate the effect of pre-operative vaginal preparation with 1% povidone iodine solution on the post-operative caesarean infectious morbidity.Methods: 72 women were enrolled in the experimental group who received 1% povidone iodine vaginal wash and 72 in the control group who did not receive any vaginal wash. The investigators were blinded to the computer-generated random number table and to the allocation group. The clinical data was recorded and after its completion, the allocation group was revealed to the investigator. The data was tabulated and statistically analyzed using SPSS 21.Results: Age, parity, BMI, gestational age, blood loss, and operative time between the two groups was comparable. Pre-operative povidone iodine vaginal wash was more effective when membranes were intact versus ruptured. With intact membranes, statistical significance was reached for postoperative fever, seroma, endometritis, gaped incisional site, and foul discharge with p value 0.012, 0.012, 0.013, 0.027 and 0.012 respectively, between group A and B. The overall infectious morbidity in the 144 subjects showed statistical significance for endometritis, and foul-smelling lochia with p value 0.049 and 0.024 respectively; urinary tract infection, hospital stay duration, and incisional wound dehiscence were higher in group B versus group A, the difference in these parameters did not reach statistical significance.Conclusions: Pre-operative vaginal cleansing with 1% povidone iodine reduced post-operative infectious morbidity more effectively in those with intact membranes than ruptured membranes.

scholarly journals COMPARATIVE STUDY OF PRE-CAESAREAN VAGINAL WASH WITH 5% POVIDONE – IODINE SOLUTION VERSUS NO WASH IN PREVENTING POSTOPERATIVE INFECTION.

2020 ◽  
pp. 44-46
Author(s):  
Sonali Deshpande ◽  
Shrinivas Gadappa ◽  
Dhanashree Lahane ◽  
Sandeep Mannikatti
Keyword(s):  
Surgical Site Infection ◽  
Wound Infection ◽  
Povidone Iodine ◽  
Prophylactic Antibiotic ◽  
Control Group ◽  
Site Infection ◽  
Iodine Solution ◽  
Interventional Group ◽  
Vaginal Wash ◽  
Povidone Iodine Solution

Objective: To evaluate the efficacy of pre-cesarean vaginal wash using 5% Povidone Iodine solution on rate of post-cesarean section (CS) surgical site infection and compared with No swabbing. Method: A Prospective Randomized controlled Trial was conducted in department of Obstetrics and Gynecology in Government medical college, Aurangabad. In interventional group, vaginal swabbing with a gauze pieces impregnated with 5% Povidone Iodine solution was done for 30 seconds. The swabbing of vagina was not performed in cases assigned to control group, however the standard surgical preparation of abdomen was done in a usual manner for both group. All subject received prophylactic antibiotic cover. Collected data was complied in pre-designed proforma and analysis was done using SPSS 15. Result: The risk of post operative fever and wound infection was significantly reduced in interventional group. No measure difference was noted in seroma and composite wound infection. Also less duration of hospital stay in interventional group was noted. No adverse effect of use of Povidone iodine was reported in the interventional group. Conclusion: Vaginal swabbing with 5% Povidone-iodine pre- LSCS is inexpensive and simple intervention even for low resource setting to decrease surgical site infection.

Vaginal Preparation With Povidone Iodine and Postcesarean Infectious Morbidity

2001 ◽  
Vol 97 (1) ◽  
pp. 147-152
Author(s):  
VIRGIL C. REID ◽  
KATHERINE E. HARTMANN ◽  
MICHAEL MCMAHON ◽  
ELIZABETH P. FRY
Keyword(s):  
Povidone Iodine ◽  
Infectious Morbidity

Preoperative vaginal preparation with povidone-iodine on post-caesarean infectious morbidity

2011 ◽  
Vol 31 (5) ◽  
pp. 400-403 ◽  
Author(s):  
M. Asghania ◽  
F. Mirblouk ◽  
M. Shakiba ◽  
R. Faraji
Keyword(s):  
Povidone Iodine ◽  
Infectious Morbidity

scholarly journals Effect of preoperative vaginal cleansing using chlorhexidine antiseptic on post cesarean section infectious morbidity

2019 ◽  
Vol 7 (1) ◽  
pp. 107
Author(s):  
Tyseer Marzouk ◽  
Hanan Abd-Elmohdy Emarah ◽  
Mai Mostafa Zaitoun
Keyword(s):  
Cesarean Section ◽  
Random Sample ◽  
Controlled Trial ◽  
Conventional Care ◽  
Elective Cesarean Section ◽  
Simple Random Sample ◽  
Morbidity Rate ◽  
Care Group ◽  
Study Group ◽  
Infectious Morbidity

Objective: This study aims to assess effect of preoperative vaginal cleansing using chlorhexidine antiseptic on post cesarean section infectious morbidity.Methods: A randomized controlled trial was conducted on a random sample of 178 singleton term pregnant woman assigned for elective cesarean section. A simple random sample was recruited from the operating room of Obstetrics and Gynecology department, Zagazig University Hospitals-Egypt. Participants were randomly assigned either to conventional care group or study group. The conventional care group was exposed to the usual abdominal scrub with Povidone-iodine solution; while the study group subjected to vaginal cleansing using chlorhexidine antiseptic solution in addition to conventional preoperative care. Data were collected using an assessment sheet for demographic and clinical data and checklist for study outcomes.Results: Post intervention, assessment of the incisional wound revealed lower overall post cesarean section infectious morbidity rate among study group compared to those received conventional care (9.0% vs. 20.2% respectively; χ2 = 4.50, p = .034). Endometritis rate was significantly lower among the study group subjects equated to those of the conventional care group (2.2% vs. 10.1% respectively; χ2 = 4.75, p = .029), meanwhile febrile morbidity and surgical site infection rates showed non-significant reduction in favor to the study group subjects (p = .469 and 0.700 respectively).Conclusions: Preoperative vaginal cleansing using chlorhexidine was an effective practice for reducing post cesarean infection; where overall post cesarean infectious morbidity rate was lower among postpartum mothers subjected to vaginal cleansing compared to those exposed to conventional care alone; supporting the study hypothesis.

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