Pharmacokinetics of a Novel Vaginal Delivery System for Testosterone and Dehydroepiandrosterone (DHEA)

2019 ◽  
Author(s):  
Keyword(s):  
Vaginal Delivery ◽  
Delivery System

scholarly journals The Successful Use of Nitroglycerin for Uterine Hyperstimulation with Fetal Heart Rate Abnormality Caused by a Controlled-Release Dinoprostone Vaginal Delivery System (PROPESS): A Case Report

Medicina ◽  
2021 ◽  
Vol 57 (5) ◽  
pp. 478
Author(s):  
Sho Takakura ◽  
Hiroaki Tanaka ◽  
Naosuke Enomoto ◽  
Shintaro Maki ◽  
Tomoaki Ikeda
Keyword(s):  
Heart Rate ◽  
Controlled Release ◽  
Vaginal Delivery ◽  
Delivery System ◽  
Fetal Heart Rate ◽  
Fetal Heart ◽  
Cervical Ripening ◽  
Emergency Cesarean ◽  
Uterine Hyperstimulation ◽  
Uterine Relaxation

The PROPESS, a controlled-release dinoprostone vaginal delivery system, is a pharmacological cervical ripening intervention and promotes cervical change causing uterine contraction. During insertion of the PROPESS, uterine hyperstimulation could occur and result in fetal heart rate (FHR) abnormality. We report a case of uterine hyperstimulation accompanied with FHR abnormality caused by the PROPESS in a pregnant woman. Postural change, oxygenation, fluid infusion, and the immediate PROPESS removal were ineffective to address the adverse event, so we administered nitroglycerin for acute uterine relaxation. The nitroglycerin resulted in uterine relaxation, and the FHR abnormality was resolved immediately, thereby preventing an emergency cesarean section. Therefore, nitroglycerin could be considered an effective option for uterine hyperstimulation accompanied with FHR abnormality caused by the PROPESS.

Development and in vitro evaluation of a mucoadhesive vaginal delivery system for progesterone

2001 ◽  
Vol 77 (3) ◽  
pp. 323-332 ◽  
Author(s):  
Claudia Valenta ◽  
Constantia E Kast ◽  
Irene Harich ◽  
Andreas Bernkop-Schnürch
Keyword(s):  
Vaginal Delivery ◽  
Delivery System ◽  
In Vitro Evaluation

Development and In Vitro Evaluation of a Mucoadhesive Vaginal Delivery System for Nystatin

2009 ◽  
Vol 98 (2) ◽  
pp. 555-564 ◽  
Author(s):  
Juliane Hombach ◽  
Thomas F. Palmberger ◽  
Andreas Bernkop‐Schnürch
Keyword(s):  
Vaginal Delivery ◽  
Delivery System ◽  
In Vitro Evaluation

Development and in vitro evaluation of a liposomal vaginal delivery system for acyclovir

2005 ◽  
Vol 106 (1-2) ◽  
pp. 34-43 ◽  
Author(s):  
Željka Pavelić ◽  
Nataša Škalko-Basnet ◽  
Jelena Filipović-Grčić ◽  
Anita Martinac ◽  
Ivan Jalšenjak
Keyword(s):  
Vaginal Delivery ◽  
Delivery System ◽  
In Vitro Evaluation

A new vaginal delivery system of amphotericin B: a dispersion of cationic liposomes in a thermosensitive gel

2010 ◽  
Vol 18 (8) ◽  
pp. 637-644 ◽  
Author(s):  
June-Woo Kang ◽  
Enkhzaya Davaa ◽  
Ye-Tae Kim ◽  
Jeong-Sook Park
Keyword(s):  
Amphotericin B ◽  
Vaginal Delivery ◽  
Delivery System ◽  
Cationic Liposomes ◽  
Thermosensitive Gel

Thiolated Cyclodextrin: Development of a Mucoadhesive Vaginal Delivery System for Acyclovir

2016 ◽  
Vol 105 (5) ◽  
pp. 1714-1720 ◽  
Author(s):  
Muhammad Ijaz ◽  
Julia Anita Griessinger ◽  
Arshad Mahmood ◽  
Flavia Laffleur ◽  
Andreas Bernkop-Schnürch
Keyword(s):  
Vaginal Delivery ◽  
Delivery System

scholarly journals PMD53 - REMOVABLE DINOPROSTONE VAGINAL DELIVERY SYSTEM: COST-CONSEQUENCES MODEL FOR CENTRAL AND EASTERN EUROPE COUNTRIES

2018 ◽  
Vol 21 ◽  
pp. S251-S252
Author(s):  
K. Pacocha ◽  
I. Pieniazek ◽  
J. Stelmachowski ◽  
J. Walczak ◽  
A. Bierut ◽  
...  
Keyword(s):  
Eastern Europe ◽  
Vaginal Delivery ◽  
Delivery System ◽  
Central And Eastern Europe ◽  
System Cost
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