Influence of Enamel Matrix Derivative (Emdogain®) on Palate Wound Healing.

2019 ◽  
Author(s):  
Keyword(s):  
Wound Healing ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Matrix Derivative

scholarly journals Angiogenic Marker Alterations Following Enamel Matrix Derivative Treatment: A Human Study

2012 ◽  
Vol 2 (1) ◽  
pp. 8
Author(s):  
Onur Özçelik ◽  
Gülşah Seydaoğlu ◽  
Murat Cömert ◽  
Eftal Yılmaz ◽  
M. Cenk Haytaç
Keyword(s):  
Wound Healing ◽  
Inflammatory Infiltrate ◽  
Soft Tissues ◽  
Human Study ◽  
Gingival Tissue ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
And Control ◽  
Angiogenic Marker ◽  
Matrix Derivative

Aim: The aim of this immunohistochemical study was to assess the expression of angiogenic markers (vascular endothelial growth factor (VEGF) and microvessel density (MVD) in enamel matrix derivative (EMD) treated retromolar soft tissues to gain further insights into the biological mechanisms involved in wound healing and EMD treatment. Methodology: In twenty healthy volunteers, gingival biopsies were obtained from the distal wedge operations of test (EMD-applied) and control sites. EMD was applied into the test sites during the operation. At the 15th post-operative day, the sample sites were re-entered and gingival tissue samples were obtained from both test and control sites. A total of 80 samples for each sites were analyzed by immunohistochemistry for inflammatory infiltrate, expression of VEGF and MVD. Results: Despite similar post-operative inflammatory infiltrate, it was found that EMD- applied sites had statistically higher VEGF-A and VEGF-C expression and MVD compared to the controls on the 15th day. (p <0.0001 for each) Conclusions: This study supports that EMD has an angiogenic potential. The findings of this immunohistochemical analysis may help to gain insight into the angiogenic effects of EMD during the early phases of wound healing.  How to cite this article: Özçelik O, Seydaoğlu G, Cömert M, Yılmaz E, Haytaç MC. Angiogenic Marker Alterations Following Enamel Matrix Derivative Treatment: A Human Study. Int Dent Res 2012;2:8-16. Linguistic Revision: The English in this manuscript has been checked by at least two professional editors, both native speakers of English.

Proline-Rich Peptide Mimics Effects of Enamel Matrix Derivative on Rat Oral Mucosa Incisional Wound Healing

2015 ◽  
Vol 86 (12) ◽  
pp. 1386-1395 ◽  
Author(s):  
Oscar Villa ◽  
Johan C. Wohlfahrt ◽  
Ibrahimu Mdla ◽  
Christiane Petzold ◽  
Janne E. Reseland ◽  
...  
Keyword(s):  
Wound Healing ◽  
Oral Mucosa ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Peptide Mimics ◽  
Proline Rich Peptide ◽  
Matrix Derivative

Effect of Enamel Matrix Derivative on Periodontal Wound Healing and Regeneration in an Osteoporotic Model

2014 ◽  
Vol 85 (11) ◽  
pp. 1603-1611 ◽  
Author(s):  
Richard J. Miron ◽  
Lingfei Wei ◽  
Shuang Yang ◽  
Oana M. Caluseru ◽  
Anton Sculean ◽  
...  
Keyword(s):  
Wound Healing ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Periodontal Wound Healing ◽  
Matrix Derivative

Effects of enamel matrix derivative on periodontal wound healing in an inflammatory environment in vitro

2011 ◽  
Vol 38 (5) ◽  
pp. 479-490 ◽  
Author(s):  
Marjan Nokhbehsaim ◽  
Jochen Winter ◽  
Birgit Rath ◽  
Andreas Jäger ◽  
Søren Jepsen ◽  
...  
Keyword(s):  
Wound Healing ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Periodontal Wound Healing ◽  
Matrix Derivative

Effects of a topical enamel matrix derivative on skin wound healing

2004 ◽  
Vol 12 (1) ◽  
pp. 100-108 ◽  
Author(s):  
Ursula Mirastschuski ◽  
Daniel Konrad ◽  
Eva Lundberg ◽  
Staale Petter Lyngstadaas ◽  
Lars N. Jorgensen ◽  
...  
Keyword(s):  
Wound Healing ◽  
Skin Wound ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Skin Wound Healing ◽  
Matrix Derivative

Enamel matrix derivative effects on palatal mucosa wound healing: Randomized clinical trial

2021 ◽  
Author(s):  
Manuela Maria Viana Miguel ◽  
Ingrid Fernandes Mathias‐Santamaria ◽  
Amanda Rossato ◽  
Laís Fernanda Ferreira Ferraz ◽  
Thiago Perez Rangel ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Wound Healing ◽  
Randomized Clinical Trial ◽  
Enamel Matrix Derivative ◽  
Enamel Matrix ◽  
Palatal Mucosa ◽  
Matrix Derivative
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