scholarly journals Deep brain stimulation for medically refractory life-threatening status dystonicus in children

2012 ◽  
Vol 9 (1) ◽  
pp. 99-102 ◽  
Author(s):  
Brian P. Walcott ◽  
Brian V. Nahed ◽  
Kristopher T. Kahle ◽  
Ann-Christine Duhaime ◽  
Nutan Sharma ◽  
...  

Generalized dystonic syndromes may escalate into persistent episodes of generalized dystonia known as status dystonicus that can be life-threatening due to dystonia-induced rhabdomyolysis and/or respiratory compromise. Treatment of these conditions usually entails parenteral infusion of antispasmodic agents and sedatives and occasionally necessitates a medically induced coma for symptom control. The authors report a series of 3 children who presented with medically intractable, life-threatening status dystonicus and were successfully treated with bilateral pallidal deep brain stimulation. Bilateral globus pallidus internus stimulation appears to be effective in the urgent treatment of medically refractory and life-threatening movement disorders.

2008 ◽  
Vol 23 (1) ◽  
pp. 131-134 ◽  
Author(s):  
Joerg Mueller ◽  
Inger M. Skogseid ◽  
Reiner Benecke ◽  
Andreas Kupsch ◽  
Thomas Trottenberg ◽  
...  

2012 ◽  
Vol 18 ◽  
pp. S150
Author(s):  
T. Mandat ◽  
H. Koziara ◽  
R. Rola ◽  
T. Tykocki ◽  
W. Bonicki ◽  
...  

2009 ◽  
Vol 24 (6) ◽  
pp. 846-853 ◽  
Author(s):  
Xavier Vasques ◽  
Laura Cif ◽  
Victoria Gonzalez ◽  
Claire Nicholson ◽  
Philippe Coubes

2019 ◽  
Vol 2019 ◽  
pp. 1-2 ◽  
Author(s):  
Lizl Lasky ◽  
Lindsay Bliss ◽  
Christos Sidiropoulos

Background. Dystonia is a ubiquitous syndrome, with a growing number of genes being continually identified. Mutations in the anoctamin-3 gene have been described to cause dystonia but the management and long-term outcomes are still largely unknown. Methods. We present here a long term, longitudinal follow up of a patient with generalized dystonia, who was treated with bilateral pallidal deep brain stimulation and was found to harbor a mutation in the anoctamin-3 gene. Results. Ongoing adjustment of stimulation settings and medications led to good and sustained dystonia control; however the patient did suffer short term relapses, manifested as dystonic crisis, which necessitated inpatient admission. Conclusion. This only the second patient to be reported with pallidal stimulation and an anoctamin-3 gene mutation. Long term outcomes seem to be favorable but larger case series are needed to confirm our findings.


2009 ◽  
Vol 15 ◽  
pp. S45
Author(s):  
B. Brodacki ◽  
H. Koziara ◽  
R. Rola ◽  
T. Tykocki ◽  
P. Nauman ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document