scholarly journals Allergic BronchoPulmonary Aspergillosis in Nepal

2014 ◽  
Vol 52 (196) ◽  
pp. 1020-1023
Author(s):  
Neha Agarwal ◽  
Prajowl Shrestha ◽  
Ramesh Chokhani
Keyword(s):  
Pulmonary Tuberculosis ◽  
Bronchial Asthma ◽  
Allergic Bronchopulmonary Aspergillosis ◽  
Case Series ◽  
Total Serum ◽  
Systemic Steroid ◽  
Serum Ige ◽  
Antitubercular Treatment ◽  
Clinical Responses ◽  
Time Of Presentation

Allergic BronchoPulmonary Aspergillosis is clinically under recognized and often misdiagnosed in Nepal. A total of 15 cases of ABPA were enrolled in this case series. Cases were followed up after the 3 months of start of treatment and clinical responses were assessed. The mean age of the patients was 33.06 ± 9.2 yrs. 80% were male. 26.6% patients were empirically on antitubercular treatment at the time of presentation. 40% patients were misdiagnosed and already treated as pulmonary Tuberculosis. 10 patients were previously treated as cases of refractory asthma. Majority of patients had significant eosinophillia and raised total serum IgE. All patients required treatment with bronchodilator and systemic steroid. 80% patients underwent remission with the treatment. Pulmonary Tuberculosis and refractory bronchial asthma are common condition that leads to the misdiagnosis of this disease.  Keywords: ABPA; bronchial asthma; central bronchiectasis; eosinophil count; serum IgE.

scholarly journals Total serum IgE and parasite: specific IgG and IgA antibodies in human strongyloidiasis

1993 ◽  
Vol 35 (4) ◽  
pp. 361-365 ◽  
Author(s):  
Cláudio L. Rossi ◽  
Emilia E. H. Takahashi ◽  
Cláudia D. Partel ◽  
Lívia G.V.L. Teodoro ◽  
Luiz J. da Silva
Keyword(s):  
Elevated Serum ◽  
Clinical Manifestations ◽  
Case Series ◽  
Total Serum ◽  
Igg Antibodies ◽  
Serum Ige ◽  
Iga Antibodies ◽  
Specific Igg ◽  
Mean Concentration ◽  
Specific Igg Antibodies

Total serum IgE, and Strongyloides - specific IgG and IgA antibodies were studied in 27 patients with parasitologically proven strongyloidiasis. Clinical manifestations in this case series were investigated by a restrospective study of the patient's records. Total serum IgE levels were elevated (greater than 250 IU/ml) in 59% of the patients (mean concentration = 1364 IU/ml). Parasite - specific IgG and IgA antibodies were detected by ELISA in the serum of 23 (85.2%) and 21 (77.8%) patients, respectively. Elevated serum IgE and clinical manifestations were not useful indexes of the presence of strongyloidiasis. On the other hand, our results support the view that serologic tests, particularly ELISA for detecting Strongyloides - specific IgG antibodies, can be usefully exploited for diagnostic purposes in strongyloidiasis.

Abstract 205: Over 5 Years Follow-up of Kawasaki Disease with Atopic Bronchial Asthma

Circulation ◽  
2015 ◽  
Vol 131 (suppl_2) ◽  
Author(s):  
Toshimi Nakamura ◽  
Tsuneyuki Nakamura ◽  
Giyo Ko ◽  
Yoko Yamashita ◽  
Chisato Akita ◽  
...  
Keyword(s):  
Kawasaki Disease ◽  
Bronchial Asthma ◽  
Allergic Disease ◽  
Total Serum ◽  
Severe Allergic Reaction ◽  
Serum Ige ◽  
Atopic Bronchial Asthma ◽  
Long Term Prognosis

Background: Recent epidemiological studies have suggested that some patients with Kawasaki disease (KD) have an atopic tendency. However, it is not clear what the long-term prognosis will be for KD-patient with allergic disease. We aim to investigate the long-term prognosis of KD-patient with allergic disease. Subjects & Methods: We studied a cohort of KD-patient (n=58, follow-up age; 9.95±1.84 years), in whom we examined total serum IgE and specific IgE at KD-onset (onset age; 2.13±1.84 years). Using retrospective patient medical record analysis, we evaluated the prevalence of bronchial asthma at onset and follow-up of KD. In addition, we examined the hospitalization rate, medical history and family history in pediatric bronchial asthma after KD-onset. Results: In our study, KD-patient had markedly higher total serum IgE and prevalence of bronchial asthma at onset of KD than the general children’s population, as reported by Japanese national government (Table 1). The prevalence of bronchial asthma at follow-up was similar to the general children’s population. 9 children had already had a diagnosis of a bronchial asthma at KD-onset. 8 children had subsequently developed bronchial asthma after KD-onset. In these 2 groups, however, 6 and 8 children, respectively, had remitted during follow-up. Nobody was hospitalized for asthmatic exacerbation after KD-onset. Conclusions: These findings demonstrate that KD-patient with atopic bronchial asthma at onset have not developed severe allergic reaction. There results provide that the pathogenic mechanism of KD might weakly or transiently provoke an elevation of total IgE and the developing of allergies.

Herpetic Whitlow of the Hand in Infants

2020 ◽  
Author(s):  
Mohammad M. Al-Qattan ◽  
Nada G. AlQadri ◽  
Ghada AlHayaza
Keyword(s):  
Bacterial Infection ◽  
Case Reports ◽  
Case Series ◽  
Individual Case ◽  
Senior Author ◽  
Secondary Bacterial Infection ◽  
Clinical Appearance ◽  
History Of ◽  
Mode Of Transmission ◽  
Time Of Presentation

Abstract Introduction Herpetic whitlows in infants are rare. Previous authors only reported individual case reports. We present a case series of six infants. Materials and Methods This is a retrospective study of six cases of herpetic whitlows in infants seen by the senior author (MMA) over the past 23 years (1995–2017 inclusive). The following data were collected: age, sex, digit involved in the hand, mode of transmission, time of presentation to the author, clinical appearance, presence of secondary bacterial infection, presence of other lesions outside the hand, method of diagnosis, treatment, and outcome. Results All six infants initially presented with classic multiple vesicles of the digital pulp. In all cases, there was a history of active herpes labialis in the mother. Incision and drainage or deroofing of the vesicles (for diagnostic purposes) resulted in secondary bacterial infection. Conclusion The current report is the first series in the literature on herpetic whitlows in infants. We stress on the mode of transmission (from the mother) and establishing the diagnosis clinically. In these cases, no need for obtaining viral cultures or polymerase chain reaction; and no medications are required. Once the vesicles are disrupted, secondary bacterial infection is frequent and a combination of oral acyclovir and intravenous antibiotics will be required.

scholarly journals Case Series of Three Patients with Rifampicin-Induced Thrombocytopenia

2020 ◽  
Author(s):  
Chandramouli M.T
Keyword(s):  
Pulmonary Tuberculosis ◽  
Adverse Reactions ◽  
Rare Complication ◽  
Case Series ◽  
Tuberculosis Treatment ◽  
Effective Drug ◽  
Antitubercular Drugs ◽  
Short Course ◽  
Life Threatening

AbstractLife-threatening adverse reactions of antitubercular drugs are uncommon; however, thrombocytopenia is one such rare complication encountered with rifampicin, isoniazid, ethambutol, and pyrazinamide. Rifampicin is the most effective drug and its use in the tuberculosis treatment led to the emergence of modern and effective short-course regimens. I am reporting case series of three patients with pulmonary tuberculosis presented with rifampicin-induced thrombocytopenia.

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