Purpose: to estimate the antibiotic resistance of Vibrio cholerae non О1/non О139 strains isolated from humans in the RostovRegion over the last 45 years. Materials and methods. Eighty six strains of V. cholerae non О1/non О139 (ctx-tcp-) were tested which had been isolated from humans in the Rostov region in 1968-2014. Antibiograms of strains tested were determined by the method of serial dilutions in solid medium. Results. In 2005-2014, as compared to 1968-1975, strains possessing multiple antibiotic resistance grew in number whereas the number of susceptible cultures decreased. The antimicrobial sensitivy spectrum of V.cholerae non О1/non О139 strains is consistent with previous records of high genome plasticity and variability of these strains. Conclusion. For successful etiotropic therapy and prevention of resistant strains spread the monitoring of antibiotic sensitivy is needed of each isolated clinical culture with subsequent timely replacement of antimicrobial in case of its inefficiency.
Comparative study of presumptive and confirmatory tests for detection of blood on serial dilutions and washed stains
