Inhibitory Effect of an Anti-oxidant, Butylated Hydroxyanisole, on the Primary in Vitro Immune Response

1977 ◽  
Vol 154 (2) ◽  
pp. 289-294 ◽  
Author(s):  
D. L. Archer ◽  
J. A. Bukovic-Wess ◽  
B. G. Smith
Keyword(s):  
Immune Response ◽  
Inhibitory Effect ◽  
Butylated Hydroxyanisole ◽  
Anti Oxidant ◽  
In Vitro Immune Response

Modulation of murine in vitro immune response by verapamil (V)

1990 ◽  
Vol 20 (3) ◽  
pp. 165-174 ◽  
Author(s):  
A.B. Singh ◽  
K. Hiehle ◽  
P. Casale ◽  
S. Gerber ◽  
S. Nayar ◽  
...  
Keyword(s):  
Immune Response ◽  
In Vitro Immune Response

Inhibition of in vitro immune response by extracts from long-term cultured lymphoid cells

1979 ◽  
Vol 42 (1) ◽  
pp. 177-182 ◽  
Author(s):  
Marie-Agnès Delpierre ◽  
Jacques Panijel ◽  
Micheline Terquem ◽  
Jacqueline Maridat
Keyword(s):  
Immune Response ◽  
Lymphoid Cells ◽  
In Vitro Immune Response

The requirement for macrophages in the in vitro immune response

1971 ◽  
Vol 2 (5) ◽  
pp. 399-410 ◽  
Author(s):  
Ken Shortman ◽  
Jon Palmer
Keyword(s):  
Immune Response ◽  
In Vitro Immune Response

scholarly journals ANTIBODY-MEDIATED SUPPRESSION OF THE IMMUNE RESPONSE IN VITRO

1970 ◽  
Vol 131 (2) ◽  
pp. 247-274 ◽  
Author(s):  
Marc Feldmann ◽  
Erwin Diener
Keyword(s):  
Immune Response ◽  
Immune Suppression ◽  
Serum Antibody ◽  
Cellular Level ◽  
Mouse Spleen ◽  
Spleen Cells ◽  
Normal Response ◽  
In Vitro Immune Response ◽  
Immune Response In Vitro

Antibody-mediated suppression of the in vitro immune response to polymerized flagellin of Salmonella adelaide and to sheep erythrocytes was studied at the cellular level. Normal mouse spleen cells, preincubated in vitro with mixtures of antigen and antibody for short periods of time before being washed, did not respond to an optimal antigenic challenge in vitro, whereas similar cells treated with antibody alone gave a normal response. The degree of immune suppression was found to depend on the time of preincubation. Significant immune suppression could be induced in as short a time as 15 min, whereas profound suppression (90%) required the incubation of cells with mixtures of antigen and antibody for 4–6 hr. Mouse spleen cells treated similarly were also unable to respond subsequently to the antigen upon transfer to lethally irradiated hosts, as measured at both the level of the antigen-reactive cell and that of serum antibody production. These results were taken as evidence that in vitro an effect of antibody-mediated suppression occurred at the level of the immunocompetent cell. Similarities between immune tolerance and antibody-mediated suppression in vitro were described, and the significance of the findings discussed in the light of current concepts of the mechanism of antibody-mediated suppression.

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