Multicomponent Reactions of Isocyanides and Dialkyl Acetylenedicarboxylate in the Presence of 2-Hydroxy-3-Methyl-2-Cyclopentene-1-One: One-Pot Synthesis of 1-Azadienes in Water
The diversity-oriented synthesis of 2,4,6-trisubstituted pyridines via K2CO3-promoted multicomponent reactions of the β-nitrostyrenes, available substituted salicylic aldehydes and ammonium acetate have been developed.