A highly efficient heterogeneous copper-catalysed cascade reaction of aryl iodides with acetamidine hydrochloride leading to primary arylamines_esi

A highly efficient heterogeneous copper-catalysed cascade reaction of aryl iodides with acetamidine hydrochloride was achieved in DMF in the presence of 10 mol% of an MCM-41-immobilised L-proline-copper(I) complex (MCM-41-L-proline-CuI) with Cs2CO3 as base, yielding a variety of primary arylamines in good to excellent yields. The new heterogeneous copper complex can be easily prepared from commercially readily available and inexpensive reagents, recovered by a simple filtration of the reaction solution and used at least seven more times without any decrease in activity.

Download Full-text

Construction of tetrahydropyranoquinoline derivativesviaan asymmetric organocatalytic aza-Michael-IED/HAD cascade reaction

Organic & Biomolecular Chemistry ◽

10.1039/c7ob02231j ◽

2017 ◽

Vol 15 (45) ◽

pp. 9630-9637 ◽

Cited By ~ 2

Author(s):

Lu Dai ◽

Yuxuan Hou ◽

Lvye Zhang ◽

Zhangtao Chen ◽

Xiaofei Zeng ◽

...

Keyword(s):

Cascade Reaction ◽

Highly Efficient

A highly efficient organocatalytic asymmetric aza-Michael-IED/HAD cascade reaction of (E)-ethyl 4-(2-(4-methylphenylsulfonamido)phenyl)-2-oxobut-3-enoate and enals is reported.

Download Full-text

Highly efficient and practical phosphoramidite–copper catalysts for amination of aryl iodides and heteroaryl bromides with alkylamines and N(H)-heterocycles

Tetrahedron ◽

10.1016/j.tet.2006.02.062 ◽

2006 ◽

Vol 62 (18) ◽

pp. 4435-4443 ◽

Cited By ~ 89

Author(s):

Zhanjin Zhang ◽

Jincheng Mao ◽

Di Zhu ◽

Fan Wu ◽

Huilin Chen ◽

...

Keyword(s):

Copper Catalysts ◽

Highly Efficient ◽

Aryl Iodides

Download Full-text

Nickel-Catalyzed Cascade Carbonylative Synthesis of N-Benzoyl Indoles from 2-Nitroalkynes and Aryl Iodides

Organic Chemistry Frontiers ◽

10.1039/d1qo01284c ◽

2021 ◽

Author(s):

Xiao-Feng Wu ◽

jun ying ◽

Lingyun Yao

Keyword(s):

Cascade Reaction ◽

Aryl Iodides

A nickel-catalyzed carbonylative cyclization of 2-nitroalkynes and aryl iodides has been developed for the expedite construction of N-benzoyl indole scaffolds. With Co2(CO)8 as the CO source, this cascade reaction proceeded...

Download Full-text

A highly efficient copper and ligand free protocol for the room temperature Sonogashira reaction

RSC Advances ◽

10.1039/c4ra09630d ◽

2015 ◽

Vol 5 (1) ◽

pp. 16-19 ◽

Cited By ~ 16

Author(s):

Ankur Gogoi ◽

Anindita Dewan ◽

Utpal Bora

Keyword(s):

Catalytic System ◽

Room Temperature ◽

Sonogashira Reaction ◽

Highly Efficient ◽

Aryl Iodides ◽

Ligand Free

A mild and efficient catalytic system based on PdCl2 and Na2SO4 has been developed for the Sonogashira reaction of aryl iodides at room temperature.

Download Full-text

ChemInform Abstract: Highly Efficient C-SeCF3Coupling of Aryl Iodides Enabled by an Air-Stable Dinuclear PdICatalyst.

ChemInform ◽

10.1002/chin.201603171 ◽

2016 ◽

Vol 47 (3) ◽

Author(s):

Marialuisa Aufiero ◽

Theresa Sperger ◽

Althea S.-K. Tsang ◽

Franziska Schoenebeck

Keyword(s):

Highly Efficient ◽

Aryl Iodides

Download Full-text

New efficient synthesis of benzofuro[2,3-b]pyrroles utilizing a reactive nitrilium trapping approach by an acid-promoted cascade addition/cyclization sequence

New Journal of Chemistry ◽

10.1039/c9nj05757a ◽

2020 ◽

Vol 44 (9) ◽

pp. 3632-3636

Author(s):

Sandip Gangadhar Balwe ◽

Yeon Tae Jeong

Keyword(s):

Cascade Reaction ◽

Efficient Synthesis ◽

One Pot ◽

Highly Efficient

The first p-TSA·H2O-catalyzed highly efficient one-pot cascade reaction for the synthesis of novel fused tricyclic benzofuro[2,3-b]pyrroles has been discovered.

Download Full-text