scholarly journals Partial Mole Coexistence with a Normal Live Fetus in Twin Pregnancy

2019 ◽  
Vol 60 (4) ◽  
pp. 234-237
Author(s):  
Saabh I. Alkateeb ◽  
Hala M. Alkhalidy
Keyword(s):  
Gestational Age ◽  
Twin Pregnancy ◽  
The Other ◽  
Normal Vaginal Delivery ◽  
Close Monitoring ◽  
Uterine Contractions ◽  
Invasive Mole ◽  
Live Fetus ◽  
Normal Placenta

We present a case of dizygotic diamiontic twin pregnancy in which one fetus was normal with normal placenta, the 2nd fetus was normal appearing with partial molar placenta. All required investigation and clinical assessments were carried out and revealing partial molar pregnancy in one fetus and normal placenta of the other one. Maternal BhCG was high for  gestational age.The patient was a 31-year-old presented to Central Private Hospital; her gestational age was 22 weeks +5 days following IVF (after 10 years of primary infertility) of diazygotic diamiontic twin pregnancy as a case of vaginal bleeding from 8 weeks of gestation with uterine contractions. The patient had gestational DM & hyperthyroidism. Appropriate treatment regarding her conditions was implemented All appropriate management was implemented. The patient continued to bleed. Within few days of admission she had premature uncomplicated labor with normal vaginal delivery (gestational age was23 Wks +3 days), both babies appeared normal, one placenta morphologically &histologically typical of H.mole. The other one completely was normal. Monitoring of serum BhCG and follow up transvaginal US was done until BhCG level returned to normal after 3 months of delivery without chemotherapy. Close monitoring of pregnancy from early stages and discussing the possible complications to mother and baby (such as baby may be chromosomally abnormal &may not survive) with parents is important to manage such complications. It is also necessary to have post-natal close follow up for maternal BhCG levels to assess any possibility of invasive mole or choriocarcinoma.

scholarly journals Live second trimester intrauterine pregnancy with invasive mole: a rare case report

2018 ◽  
Vol 7 (4) ◽  
pp. 1657 ◽  
Author(s):  
Muskaan Chhabra ◽  
Rekha Daver
Keyword(s):  
Malignant Transformation ◽  
Gestational Age ◽  
Gestational Trophoblastic Disease ◽  
Molar Pregnancy ◽  
Intrauterine Pregnancy ◽  
Beta Hcg ◽  
Rare Case Report ◽  
Invasive Mole ◽  
Live Fetus

Gestational trophoblastic disease or gestational trophoblastic neoplasia is a collective term used to describe hydatiform mole, invasive mole, choriocarcinoma and placental site trophoblastic tumours. Since any molar pregnancy has the potential to develop into invasive mole these patients should be carefully monitored for development of malignant disease. Here we are reporting a case of invasive molar pregnancy with a single live fetus of 17 weeks gestational age. A 24 years old woman, G3P2L2 with a history of amenorrhea since approximately 5 months presented with profuse per vaginal bleeding. Ultrasound showed presence of live fetus of approximate gestational age of 17 weeks. Along with the fetus there was also presence of cystic areas with no vascularity s/o Hydatiform mole. In view of continued bleeding and severe anemia pregnancy was terminated and fetus along with vesicular tissue was expelled. On follow up Beta hcg titers showed increasing trend over the next week. Repeat USG showed extension of molar tissue into the myometrium. In view of this she was given 3 cycles of chemotherapy and eventually was discharged. She was followed up regularly with no e/o recurrence. Presence of viable fetus along with hydatiform mole is a rare occurrence in obstetric practice. After termination of pregnancy these patients should undergo follow up ultrasound and serial beta HCG titers to detect the malignant transformation. Rising beta HCG titers and invasion of myometrium on ultrasound are the ominous features suggesting malignant transformation and should be treated accordingly.

CASE SERIES OF INVASIVE MOLE - A LEARNING EXPERIENCE.

2021 ◽  
pp. 22-23
Author(s):  
Japhia David ◽  
Vrunda Joshi ◽  
Jebin Aaron Devarajan
Keyword(s):  
Learning Experience ◽  
Color Doppler ◽  
Case Series ◽  
Normal Vaginal Delivery ◽  
Retained Products Of Conception ◽  
Products Of Conception ◽  
Secondary Postpartum Hemorrhage ◽  
Invasive Mole ◽  
Retained Products

This case series is intended to study the earliest possible modes of diagnosis of invasive mole and its management. In this case series, three scenarios where invasive mole presenting as hypervascular retained products of conception, as acute abdomen due to a perforating lesion and as secondary postpartum hemorrhage following a full term normal vaginal delivery are described. Inferred from the case scenarios, ultrasound with color Doppler can be used as a rst investigation to reduce the time to diagnose interval. Management includes medical treatment with intravenous methotrexate and surgical treatment with a fertility-preserving resection or hysterectomy. Strict ß-HCG follow up is required to prevent missing the diagnosis of malignant transformation of mole.

scholarly journals A twin pregnancy with a hydatidiform mole and a coexisting live fetus: prenatal diagnosis, treatment, and follow-up

2017 ◽  
Vol 17 (71) ◽  
pp. 299-305 ◽  
Author(s):  
Antonio Braga ◽  
◽  
Bruna Obeica ◽  
Heron Werner ◽  
Sue Yazaki Sun ◽  
...  
Keyword(s):  
Prenatal Diagnosis ◽  
Twin Pregnancy ◽  
Hydatidiform Mole ◽  
Live Fetus

scholarly journals Twin pregnancy with complete hydatiform mole and coexisting live fetus: A rare case report

2019 ◽  
pp. 31-34
Author(s):  
Swati Agrawal ◽  
Kiran Aggarwal ◽  
Anjali Singh ◽  
Khushbu Saha ◽  
Amrita Mishra ◽  
...  
Keyword(s):  
Rare Case ◽  
Twin Pregnancy ◽  
Gestational Trophoblastic Disease ◽  
Rare Entity ◽  
Trophoblastic Disease ◽  
Complete Mole ◽  
Beta Hcg ◽  
Rare Case Report ◽  
Live Fetus

Twin pregnancy with one live fetus and one complete mole, also known as CMCF i.e. complete molar pregnancy with coexisting live fetus is a rare entity in obstetrics. This combination is associated with increased incidences of spontaneous abortions, vaginal bleeding, prematurity, intrauterine demise, pre-eclampsia, uterine ruptures, theca lutein cysts, persistent gestational trophoblastic disease. We report a rare case of a 24-year-old patient with CMCF at 14 weeks of gestation. After confirming the diagnosis, ruling out malignancy and proper counselling, decision was taken to continue her pregnancy. However, the patient had spontaneous abortion at 15 weeks of gestation. Her serum beta Hcg has shown a decreasing trend in her follow up visits with no signs suggestive of persistent gestational trophoblastic disease.

The Fate of “Small Twins”: A Four-year Follow-up Study of Low Birthweight and Prematurely Born Twins

1992 ◽  
Vol 41 (2-3) ◽  
pp. 97-104 ◽  
Author(s):  
B. Alin Åkerman ◽  
P.A. Thomassen
Keyword(s):  
Emotional Development ◽  
Twin Pregnancy ◽  
Low Birthweight ◽  
Mental Development ◽  
The Other ◽  
Total Group ◽  
Developmental Problems ◽  
Follow Up Study

AbstractThis follow-up study of twins includes 35 families from the Stockholm area. One section concerns the physical and mental development of the twins. The other sections compare the development of the children with their parents' expectations of them and the parents' feelings about the delivery. Seven twin pairs (20%) in the total group were born before 37 complete gestational weeks. Thirty-seven of the twins weighed less than 2,500g at birth; of these, 23 (9 boys and 14 girls) weighed less than 2,500g, although they were born after 37 gestational weeks. At four years of age, 22 of the 68 twins still showed some impairment of locomotor, language/speech and emotional development, as assessed by the Griffiths Mental Development Scales. All the prematurely born and small-for-date infants were in this group. There also seems to be a relationship between developmental problems and the mother's negative or ambivalent expectations concerning the twin pregnancy.

scholarly journals Management of twin pregnancy with a hydatidiform mole and surviving healthy co-existent fetus

2017 ◽  
Vol 6 (12) ◽  
pp. 5636
Author(s):  
Hale Goksever Celik ◽  
Gözde Meriç Demirezen ◽  
Baki Erdem ◽  
Alev Atış Aydın ◽  
Volkan Ülker
Keyword(s):  
Maternal Morbidity ◽  
Twin Pregnancy ◽  
Hydatidiform Mole ◽  
Uterine Cavity ◽  
First Trimester ◽  
Molar Pregnancy ◽  
Complete Mole ◽  
Live Fetus ◽  
Twin Pregnancies ◽  
Normal Placenta

Twin pregnancies with complete mole and a coexisting live fetus are rare obstetric conditions seen in 1 case of 22000 to 100000 pregnancies. In our case, a twin molar pregnancy was diagnosed in the first trimester by ultrasound. In a 27-year-old patient with the first pregnancy, a 12-week live fetus with a normal placenta and a twin molar pregnancy appearance were observed on a routine ultrasonographic examination of the uterine cavity. Twin molar pregnancies are reported to be terminated by live birth in the literature, but termination of pregnancy is an important option to prevent maternal morbidity since molar pregnancy may lead to complications ranging from theca lutein cysts to gestational trophoblastic neoplasia.

scholarly journals Twin-Twin transfusion syndrome: a case report

2020 ◽  
Vol 9 (3) ◽  
pp. 1282
Author(s):  
Romi Bansal ◽  
Jasleen Kaur ◽  
Priyanka .
Keyword(s):  
Case Report ◽  
Gestational Age ◽  
Twin Pregnancy ◽  
The Other ◽  
Morbidity And Mortality ◽  
Perinatal Morbidity ◽  
Monochorionic Twin

Twin to twin transfusion syndrome is a rare but serious complication of monochorionic twin pregnancy. It is characterized by the development of abnormal placental vascular communication from one foetus (donor) to the other foetus (recipient). If left untreated it led to high rates of perinatal morbidity and mortality due to its poorly understood etiology and difficulty in diagnosing and treatment. Authors report a case of twin to twin transfusion syndrome in 24 years old primigravida with gestational age of 18 weeks 5 days diagnosed on ultrasound.

scholarly journals A case of prenatal diagnosis of meckel-gruber syndrome in one of the dizygotic twin of a naturally conceived pregnancy

2021 ◽  
Author(s):  
Akshay Rohatgi ◽  
Anupama Tandon
Keyword(s):  
Prenatal Diagnosis ◽  
Vaginal Delivery ◽  
Twin Pregnancy ◽  
Hepatic Cyst ◽  
The Other ◽  
Normal Vaginal Delivery ◽  
Dizygotic Twin ◽  
Cystic Kidneys ◽  
Occipital Encephalocele ◽  
Normal Twin

Meckel-Gruber syndrome in one twin of a naturally conceived dizygotic twin pregnancy is largely unknown and has not been reported till date. This report illustrates the sonographic features in a case of 20-week twin pregnancy where one twin had an occipital encephalocele, bilateral enlarged and cystic kidneys, hepatic cyst and oligohydramnios but the other twin was normal. The affected twin succumbed within few days after normal vaginal delivery while the normal twin survived and is healthy.

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