scholarly journals Identification and Characterisation of cis-Regulatory Elements Upstream of the Human Receptor Tyrosine Kinase Gene MERTK

2020 ◽  
pp. 1-14
Author(s):  
Alexander D. Walsh ◽  
Laura J. Johnson ◽  
Alexandra J. Harvey ◽  
Trevor J. Kilpatrick ◽  
Michele D. Binder

2000 ◽  
Vol 67 (4) ◽  
pp. 822-831 ◽  
Author(s):  
Georg C. Schwabe ◽  
Sigrid Tinschert ◽  
Christian Buschow ◽  
Peter Meinecke ◽  
Gerhard Wolff ◽  
...  


1993 ◽  
Vol 7 (3) ◽  
pp. 144-151 ◽  
Author(s):  
Elina Armstrong ◽  
Kumar Kastury ◽  
Olga Aprelikova ◽  
Florencia Bullrich ◽  
Christian Nezelof ◽  
...  


Genetics ◽  
1991 ◽  
Vol 128 (2) ◽  
pp. 251-267 ◽  
Author(s):  
R V Aroian ◽  
P W Sternberg

Abstract The let-23 gene, which encodes a putative tyrosine kinase of the epidermal growth factor (EGF) receptor subfamily, has multiple functions during Caenorhabditis elegans development. We show that let-23 function is required for vulval precursor cells (VPCs) to respond to the signal that induces vulval differentiation: a complete loss of let-23 function results in no induction. However, some let-23 mutations that genetically reduce but do not eliminate let-23 function result in VPCs apparently hypersensitive to inductive signal: as many as five of six VPCs can adopt vulval fates, in contrast to the three that normally do. These results suggest that the let-23 receptor tyrosine kinase controls two opposing pathways, one that stimulates vulval differentiation and another that negatively regulates vulval differentiation. Furthermore, analysis of 16 new let-23 mutations indicates that the let-23 kinase functions in at least five tissues. Since various let-23 mutant phenotypes can be obtained independently, the let-23 gene is likely to have tissue-specific functions.





1998 ◽  
Vol 78 (1-2) ◽  
pp. 47-61 ◽  
Author(s):  
Caroline Moreau-Fauvarque ◽  
Emmanuel Taillebourg ◽  
Elisabeth Boissoneau ◽  
Jacqueline Mesnard ◽  
Jean-Maurice Dura


1997 ◽  
Vol 44 (3) ◽  
pp. 242-252 ◽  
Author(s):  
Vera Gamulin ◽  
Alexander Skorokhod ◽  
Vadim Kavsan ◽  
Isabel M. Müller ◽  
Werner E. G. Müller


2000 ◽  
Vol 19 (5) ◽  
pp. 291-300 ◽  
Author(s):  
Jaemin Jeong ◽  
Sunga Choi ◽  
Changkyu Gu ◽  
Hansoo Lee ◽  
Soochul Park




1999 ◽  
Vol 96 (19) ◽  
pp. 10869-10874 ◽  
Author(s):  
J. K. Doherty ◽  
C. Bond ◽  
A. Jardim ◽  
J. P. Adelman ◽  
G. M. Clinton


Sign in / Sign up

Export Citation Format

Share Document