Optical and SPION-Enhanced MR Imaging Shows that trans-Stilbene Inhibitors of NF-κB Concomitantly Lower Alzheimer's Disease Plaque Formation and Microglial Activation in AβPP/PS-1 Transgenic Mouse Brain

Nathan O. Solberg; Ryan Chamberlin; Jenette R. Vigil; Lorraine M. Deck; John E. Heidrich; David C. Brown; Christina I. Brady; Thomas A. Vander Jagt; Michael Garwood; Marco Bisoffi; Virginia Severns; David L. Vander Jagt; Laurel O. Sillerud

doi:10.3233/jad-131031

Optical and SPION-Enhanced MR Imaging Shows that trans-Stilbene Inhibitors of NF-κB Concomitantly Lower Alzheimer's Disease Plaque Formation and Microglial Activation in AβPP/PS-1 Transgenic Mouse Brain

Journal of Alzheimer s Disease ◽

10.3233/jad-131031 ◽

2014 ◽

Vol 40 (1) ◽

pp. 191-212 ◽

Cited By ~ 30

Author(s):

Nathan O. Solberg ◽

Ryan Chamberlin ◽

Jenette R. Vigil ◽

Lorraine M. Deck ◽

John E. Heidrich ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mr Imaging ◽

Transgenic Mouse ◽

Mouse Brain ◽

Microglial Activation ◽

Plaque Formation ◽

Trans Stilbene

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Inhibition of Microglial Activation Protects Hippocampal Neurogenesis and Improves Cognitive Deficits in a Transgenic Mouse Model for Alzheimer’s Disease

Neurodegenerative Diseases ◽

10.1159/000330363 ◽

2012 ◽

Vol 9 (4) ◽

pp. 187-198 ◽

Cited By ~ 86

Author(s):

Barbara Biscaro ◽

Olle Lindvall ◽

Giuseppina Tesco ◽

Christine T. Ekdahl ◽

Roger M. Nitsch

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Cognitive Deficits ◽

Microglial Activation ◽

Transgenic Mouse Model ◽

Hippocampal Neurogenesis

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Evidence that a synthetic amyloid-ß oligomer-binding peptide (ABP) targets amyloid-ß deposits in transgenic mouse brain and human Alzheimer’s disease brain

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2014.02.064 ◽

2014 ◽

Vol 445 (3) ◽

pp. 656-660 ◽

Cited By ~ 2

Author(s):

Balu Chakravarthy ◽

Shingo Ito ◽

Trevor Atkinson ◽

Chantal Gaudet ◽

Michel Ménard ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Transgenic Mouse ◽

Mouse Brain ◽

Binding Peptide

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SPION-Enhanced Magnetic Resonance Imaging of Alzheimer's Disease Plaques in AβPP/PS-1 Transgenic Mouse Brain

Journal of Alzheimer s Disease ◽

10.3233/jad-121171 ◽

2013 ◽

Vol 34 (2) ◽

pp. 349-365 ◽

Cited By ~ 42

Author(s):

Laurel O. Sillerud ◽

Nathan O. Solberg ◽

Ryan Chamberlain ◽

Robert A. Orlando ◽

John E. Heidrich ◽

...

Keyword(s):

Magnetic Resonance Imaging ◽

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Magnetic Resonance ◽

Transgenic Mouse ◽

Mouse Brain ◽

Resonance Imaging

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Development of a novel amyloid specific gadolinium contrast agent for MR imaging modality in alzheimer's disease mouse brain

IBRO Reports ◽

10.1016/j.ibror.2019.07.1364 ◽

2019 ◽

Vol 6 ◽

pp. S429

Author(s):

Ahrum Baek ◽

Garam Choi ◽

Hee-Kyung Kim ◽

Yongmin Chang

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mr Imaging ◽

Contrast Agent ◽

Mouse Brain ◽

Imaging Modality ◽

Gadolinium Contrast ◽

Gadolinium Contrast Agent

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Binding of the Positron Emission Tomography Tracer Pittsburgh Compound-B Reflects the Amount of Amyloid- in Alzheimer's Disease Brain But Not in Transgenic Mouse Brain

Journal of Neuroscience ◽

10.1523/jneurosci.2990-05.2005 ◽

2005 ◽

Vol 25 (46) ◽

pp. 10598-10606 ◽

Cited By ~ 260

Author(s):

W. E. Klunk

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Positron Emission Tomography ◽

Transgenic Mouse ◽

Mouse Brain ◽

Emission Tomography ◽

Positron Emission Tomography Tracer ◽

Pittsburgh Compound B ◽

Positron Emission

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Mutant ubiquitin decreases amyloid β plaque formation in a transgenic mouse model of Alzheimer’s disease

Neurochemistry International ◽

10.1016/j.neuint.2012.07.007 ◽

2012 ◽

Vol 61 (5) ◽

pp. 739-748 ◽

Cited By ~ 24

Author(s):

Paula van Tijn ◽

Frank J.A. Dennissen ◽

Romina J.G. Gentier ◽

Barbara Hobo ◽

Denise Hermes ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Amyloid Β ◽

Transgenic Mouse Model ◽

Plaque Formation ◽

Model Of Alzheimer’S Disease

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Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models

Neurobiology of Disease ◽

10.1016/j.nbd.2015.11.005 ◽

2016 ◽

Vol 85 ◽

pp. 187-205 ◽

Cited By ~ 20

Author(s):

Teemu Natunen ◽

Mari Takalo ◽

Susanna Kemppainen ◽

Stina Leskelä ◽

Mikael Marttinen ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Transgenic Mouse ◽

Mouse Brain

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The distribution profile and oxidation states of biometals in APP transgenic mouse brain: dyshomeostasis with age and as a function of the development of Alzheimer's disease

Metallomics ◽

10.1039/c2mt00104g ◽

2012 ◽

Vol 4 (3) ◽

pp. 289 ◽

Cited By ~ 28

Author(s):

Huajian Wang ◽

Meng Wang ◽

Bing Wang ◽

Ming Li ◽

Hanqing Chen ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Transgenic Mouse ◽

Mouse Brain ◽

Oxidation States ◽

Distribution Profile

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Ultrastructural Abnormalities in APP/PSEN1 Transgenic Mouse Brain as the Alzheimer's Disease Model

Applied Microscopy ◽

10.9729/am.2012.42.4.179 ◽

2012 ◽

Vol 42 (4) ◽

pp. 179-185 ◽

Cited By ~ 4

Author(s):

Mi Jeong Kim ◽

Yang Hoon Huh ◽

Ki Ju Choi ◽

Sangmi Jun ◽

A Reum Je ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Transgenic Mouse ◽

Mouse Brain ◽

Disease Model

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Transgenic mouse brain histopathology resembles early Alzheimer's disease

Annals of Neurology ◽

10.1002/ana.410350514 ◽

1994 ◽

Vol 35 (5) ◽

pp. 598-607 ◽

Cited By ~ 83

Author(s):

L. S. Higgins ◽

D. M. Holtzman ◽

J. Rabin ◽

W. C. Mobley ◽

B. Cordell

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Transgenic Mouse ◽

Mouse Brain ◽

Early Alzheimer’S Disease

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