scholarly journals Are Semantic Annotators Able to Extract Relevant Complexity-Related Concepts from Clinical Notes?

2021 ◽  
Author(s):  
Akram Redjdal ◽  
Jacques Bouaud ◽  
Joseph Gligorov ◽  
Brigitte Séroussi

Clinical decision support systems (CDSSs) implementing cancer clinical practice guidelines (CPGs) have the potential to improve the compliance of decisions made by multidisciplinary tumor boards (MTB) with CPGs. However, guideline-based CDSSs do not cover complex cases and need time for discussion. We propose to learn how to predict complex cancer cases prior to MTBs from breast cancer patient summaries (BCPSs) resuming clinical notes. BCPSs being unstructured natural language textual documents, we implemented four semantic annotators (ECMT, SIFR, cTAKES, and MetaMap) to assess whether complexity-related concepts could be extracted from clinical notes. On a sample of 24 BCPSs covering 35 complexity reasons, ECMT and MetaMap were the most efficient systems with a performance rate of 60% (21/35) and 49% (17/35), respectively. When using the four annotators in sequence, 69% of complexity reasons were extracted (24/35 reasons).

2021 ◽  
Author(s):  
My-Anh Le Thien ◽  
Akram Redjdal ◽  
Jacques Bouaud ◽  
Brigitte Seroussi

Using guideline-based clinical decision support systems (CDSSs) has improved clinical practice, especially during multidisciplinary tumour boards (MTBs) in cancer patient management. However, MTBs have been reported to be overcrowded, with limited time to discuss all cases. Complex breast cancer cases that need further MTB discussions should have priority in the organization of MTBs. In order to optimize MTB workflow, we attempted to predict complex cases defined as non-compliant cases despite the use of the decision support system OncoDoc. After previously obtaining insufficient performance with machine learning algorithms, we tested Multi Layer Perceptron for classification, compared various samplers to compensate data imbalance combined with cross- validation, and optimized all models with hyperparameter tuning and feature selection with no improvement and lacklustre results (F1-score: 31.4%).


Author(s):  
David José Murteira Mendes ◽  
Irene Pimenta Rodrigues ◽  
César Fonseca

A question answering system to help clinical practitioners in a cardiovascular healthcare environment to interface clinical decision support systems can be built by using an extended discourse representation structure, CIDERS, and an ontology framework, Ontology for General Clinical Practice. CIDERS is an extension of the well-known DRT (discourse representation theory) structures, intending to go beyond single text representation to embrace the general clinical history of a given patient represented in an ontology. The Ontology for General Clinical Practice improves the currently available state-of-the-art ontologies for medical science and for the cardiovascular specialty. The chapter shows the scientific and philosophical reasons of its present dual structure with a deeply expressive (SHOIN) terminological base (TBox) and a highly computable (EL++) assertions knowledge base (ABox). To be able to use the current reasoning techniques and methodologies, the authors made a thorough inventory of biomedical ontologies currently available in OWL2 format.


Author(s):  
David José Murteira Mendes ◽  
Irene Pimenta Rodrigues ◽  
César Fonseca

A question answering system to help clinical practitioners in a cardiovascular healthcare environment to interface clinical decision support systems can be built by using an extended discourse representation structure, CIDERS, and an ontology framework, Ontology for General Clinical Practice. CIDERS is an extension of the well-known DRT (discourse representation theory) structures, intending to go beyond single text representation to embrace the general clinical history of a given patient represented in an ontology. The Ontology for General Clinical Practice improves the currently available state-of-the-art ontologies for medical science and for the cardiovascular specialty. The chapter shows the scientific and philosophical reasons of its present dual structure with a deeply expressive (SHOIN) terminological base (TBox) and a highly computable (EL++) assertions knowledge base (ABox). To be able to use the current reasoning techniques and methodologies, the authors made a thorough inventory of biomedical ontologies currently available in OWL2 format.


Cancers ◽  
2020 ◽  
Vol 12 (2) ◽  
pp. 369 ◽  
Author(s):  
Claudia Mazo ◽  
Cathriona Kearns ◽  
Catherine Mooney ◽  
William M. Gallagher

Breast cancer is the most frequently diagnosed cancer in women, with more than 2.1 million new diagnoses worldwide every year. Personalised treatment is critical to optimising outcomes for patients with breast cancer. A major advance in medical practice is the incorporation of Clinical Decision Support Systems (CDSSs) to assist and support healthcare staff in clinical decision-making, thus improving the quality of decisions and overall patient care whilst minimising costs. The usage and availability of CDSSs in breast cancer care in healthcare settings is increasing. However, there may be differences in how particular CDSSs are developed, the information they include, the decisions they recommend, and how they are used in practice. This systematic review examines various CDSSs to determine their availability, intended use, medical characteristics, and expected outputs concerning breast cancer therapeutic decisions, an area that is known to have varying degrees of subjectivity in clinical practice. Utilising the methodology of Kitchenham and Charter, a systematic search of the literature was performed in Springer, Science Direct, Google Scholar, PubMed, ACM, IEEE, and Scopus. An overview of CDSS which supports decision-making in breast cancer treatment is provided along with a critical appraisal of their benefits, limitations, and opportunities for improvement.


2021 ◽  
pp. 019459982110045
Author(s):  
Taylor C. Standiford ◽  
Janice L. Farlow ◽  
Michael J. Brenner ◽  
Marisa L. Conte ◽  
Jeffrey E. Terrell

Objective To offer practical, evidence-informed knowledge on clinical decision support systems (CDSSs) and their utility in improving care and reducing costs in otolaryngology–head and neck surgery. This primer on CDSSs introduces clinicians to both the capabilities and the limitations of this technology, reviews the literature on current state, and seeks to spur further progress in this area. Data Sources PubMed/MEDLINE, Embase, and Web of Science. Review Methods Scoping review of CDSS literature applicable to otolaryngology clinical practice. Investigators identified articles that incorporated knowledge-based computerized CDSSs to aid clinicians in decision making and workflow. Data extraction included level of evidence, Osheroff classification of CDSS intervention type, otolaryngology subspecialty or domain, and impact on provider performance or patient outcomes. Conclusions Of 3191 studies retrieved, 11 articles met formal inclusion criteria. CDSS interventions included guideline or protocols support (n = 8), forms and templates (n = 5), data presentation aids (n = 2), and reactive alerts, reference information, or order sets (all n = 1); 4 studies had multiple interventions. CDSS studies demonstrated effectiveness across diverse domains, including antibiotic stewardship, cancer survivorship, guideline adherence, data capture, cost reduction, and workflow. Implementing CDSSs often involved collaboration with health information technologists. Implications for Practice While the published literature on CDSSs in otolaryngology is finite, CDSS interventions are proliferating in clinical practice, with roles in preventing medical errors, streamlining workflows, and improving adherence to best practices for head and neck disorders. Clinicians may collaborate with information technologists and health systems scientists to develop, implement, and investigate the impact of CDSSs in otolaryngology.


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