scholarly journals Basal Cell Adenoma: About Four Cases

2020 ◽  
Vol 3 (1) ◽  

Benign tumor of the salivary glands, composed of basaloid cells of architecture most often ductal and tubular or in nests (OMS 2017). We report the case of 4 patients carrying basal cell adenoma diagnosed at the department of pathological anatomy CHU MOHAMMED VI MARRAKECH. These are three women and one man. The average age was 49 years old. The clinical examination found a unilateral parotid mass gradually increasing in size. All the patients benefited from an ultrasound which was in favor of a homogeneous hypoechoic lobulated formation with posterior reinforcement evoking a pleomorphic adenoma. The patients benefited from a total parotidectomy. Macroscopic examination found a thick-walled, hemorrhagic-cystic formation in one patient. Microscopic examination showed a benign encapsulated tumor proliferation of compact architecture, in situ clusters and in channels with eosinophilic contents. . The epithelial cells have a basaloid appearance bordered at the periphery by a palisade cell base. They are of small to medium size, provided with ovoid cores with fine chromatin. The cytoplasm is abundant basophilic. The myoepithelial cells are sometimes cuboid, sometimes fusiform. The nuclei are discreetly elongated hyperchromic. The cytoplasm is scarce eosinophilic.The basal cell adenoma is a rare salivary tumor representing less than 3.7%. It occurs mainly in the elderly with a range of 57 to 70 years. Clinically, it is in most cases a mobile solitary mass of firm consistency. The tumor has a monomorphic appearance due to the predominance of basaloid cells. The differential diagnosis is primarily with basal cell adenocarcinoma and adenoid cystic carcinoma.

2017 ◽  
Vol 23 (4) ◽  
pp. 184-188
Author(s):  
Ananya Madiyal ◽  
Babu G. Subhas ◽  
Vidya Ajila ◽  
Shruthi Hegde

Abstract Basal cell adenocarcinoma is an unusual basaloid tumour that usually affects the parotid and very rarely involves the submandibular or minor salivary glands. It constitutes 1.6% of all salivary gland tumours and occurs as an asymptomatic freely mobile mass with occasional lymph node metastasis. Differentiation from benign salivary gland tumours like basal cell adenoma is accomplished by determining the depth of tumour invasion and patterns of growth or infiltration. Although it is categorised as a low-grade malignancy, it has a high propensity for recurrence. Surgical excision with a wide margin is the preferred course of treatment with radiotherapy being reserved only for tumours of the minor salivary glands with a diffuse pattern of infiltration. We present here a case of basal cell adenocarcinoma with a rare presentation in the minor salivary glands of the tongue which arose from a previously treated basal cell adenoma in the same site.


1996 ◽  
Vol 115 (1) ◽  
pp. 150-151 ◽  
Author(s):  
Ashutosh Kacker ◽  
Volkan Adsay ◽  
Arnold Komisar

The term basal cell adenoma was used by Kleinsasser and Klien 1 in 1967 to describe benign salivary gland tumors comprised of a single type of epithelium. Basal cell adenocarcinoma is a relatively new entity, and there are only a few cases reported in the literature. It has a morphology like that of a basal cell adenoma but has growth characteristics of a malignant neoplasm.


2020 ◽  
Author(s):  
Tetsuya Terada ◽  
Ryo Kawata ◽  
Masaaki Higashino ◽  
Yoshitaka Kurisu ◽  
Hiroko Kuwabara ◽  
...  

1990 ◽  
Vol 104 (2) ◽  
pp. 150-151 ◽  
Author(s):  
G. E. Murty ◽  
A. R. Welch ◽  
J. V. Soames

AbstractA case of basal cell adenocarcinoma of the parotid gland is reported. Histologically it is to be distinguished from basal cell adenoma and adenoid cystic carcinoma. Clinically the presentation may appear benign. Surgical excision is the treatment of choice. The prognosis is uncertain because of lack of follow-up data.


2000 ◽  
Vol 124 (3) ◽  
pp. 401-405 ◽  
Author(s):  
Richard J. Zarbo ◽  
Anil R. Prasad ◽  
Joseph A. Regezi ◽  
Allen M. Gown ◽  
Adnan T. Savera

Abstract Objective.—To evaluate cellular composition of salivary gland adenomas using 3 monoclonal antibodies that recognize a smooth muscle phenotype confirmed to be sensitive for myoepithelial differentiation. Design.—Immunohistochemical evaluation of 25 salivary gland basal cell and canalicular adenomas. Setting.—Archival pathology material from the files of Henry Ford Hospital, Detroit, Mich, and the University of California at San Francisco. Results.—All basal cell adenoma variants exhibit some degree of myoepithelial cell participation with periductal, epithelioid, and spindled (stromal-like) morphologic structures. Only the canalicular adenomas, even if mixed with trabecular and solid patterns, are devoid of staining with these 3 antibodies, suggesting an adenoma composed exclusively of ductal luminal cells. Conclusions.—There is an overlapping histomorphologic and common cellular composition of the basal cell adenoma variants with other recognized adenomas, such as pleomorphic adenoma and myoepithelioma. Relative differentiation toward 3 cell phenotypes (ductal luminal, basal, and myoepithelial) and the character of extracellular matrix production in varying proportions by the neoplastic myoepithelial cells distinguishes the spectrum of salivary gland adenomas identified in current classification schemes.


Sign in / Sign up

Export Citation Format

Share Document