scholarly journals The Impact of Preoperative Anaemia on Early Outcomes after Off-pump Coronary Artery Bypass Grafting

2021 ◽  
Vol 36 (1) ◽  
pp. 47-54
Author(s):  
Sanjay Kumar Raha ◽  
Smriti Kana Biswas ◽  
Sorower Hossain ◽  
Md Salahuddin Rahaman ◽  
Khan Muhammad Fahim Bin Enayet ◽  
...  

Introduction: In cardiac surgery, anaemia itself or combined with other risk factors has been found to be a major predictor for adverse outcome both preoperatively and postoperatively and even during extracorporeal circulation, but data about the specific tolerance of Coronary Artery Bypass Graft (CABG) patients for anaemia are conflicting and may in part be confounded by the effects of bypass surgery. Objectives: This study was performed in the National Institute of Cardiovascular Diseases (NICVD) to observe whether the early outcomes of Off-Pump CABG (OPCAB)were affected by pre-operative haematocrit levels. Methods: A total of 200 patients who underwent isolated OPCAB between January 2015 and December 2020 were retrospectively selected and purposively allocated into two groups: a)100 patients having preoperative anaemia and b) 100 patients without preoperative anaemia. Preoperative, per-operative and early post-operative variables were recorded, compiled and compared. Results: Preoperative characteristics were homogenously distributed between two groups other than haemoglobin level. Female patients had lower haemoglobin in each group. More patients of anaemic group required intraoperative and postoperative blood transfusion. The amount of blood loss and transfused blood products was also higher in anaemic patients. The ventilation time, length of ICU and post-operative hospital stay were significantly higher among anaemic patients. Among the post-operative complications, only the incidence of renal dysfunction was significantly higher among anaemic patients. Conclusion:This study has showed that anaemic patients undergoing OPCAB had an increased risk of postoperative adverse events. Importantly, the extent of preexisting comorbidities substantially affected perioperative anaemia tolerance. Therefore, preoperative risk assessment, optimization and subsequent therapeutic strategies, such as blood transfusion, should take into account both the individual level of preoperative haemoglobin and the extent of concomitant risk factors. Bangladesh Heart Journal 2021; 36(1) : 47-54

2021 ◽  
Vol 8 (3) ◽  
pp. 452-459
Author(s):  
Brejesh Ravi Varma ◽  
Salman Mohamed Kutty C ◽  
Prashanth Khadanga ◽  
Nirmal Sheshagiri ◽  
Ajish Varghese Cheruvathur

Cardiovascular disease, especially coronary heart disease is increasing to a great extent globally and in India. Off pump Coronary artery bypass graft is one of the surgical modalities in the treatment of Coronary artery heart disease. Blood/ blood component transfusion is one of the essential roles during/immediate postoperative period of off pump coronary artery bypass graft surgery. Though there are few benefits due to blood transfusion, the demerits outweigh the merits of blood transfusion. Hence identification of predisposing factors for need of blood /blood component transfusions will enhance us to understand the indications and the ways to minimize it. To determine the predisposing factors that influence the need for blood transfusion during off pump coronary artery bypass graft and to measure their strength of association. This cross-sectional study was done in a tertiary care cardiac center in India between March and September 2016 on 196 patients. The participants were from both sexes, aged between 40-70 years, undergoing elective or emergency OPCABG under general anaesthesia. Information on Demographic data and comorbid illnesses were elicited. Vitals and other hemodynamic parameters were recorded during preoperative, intra operative and post operative periods. Total amount of anticoagulant (heparin) used, activated clotting time (ACT) after 3 minutes of anticoagulation, total duration of graft harvest (time from start of first graft harvesting to end of last graft harvest), total number of grafts taken, total duration for anastamoses (time from start of anastamosis to end of last graft anastamosis), total blood loss and total amount of blood transfused were noted. The intra-operative factors included total intra-operative heparin used, total protamine used, total number of grafts used for anastamoses, total duration of graft anastamoses, total duration of surgery, total duration of anaesthesia, total intra-operative blood loss and insertion of IABP intra-operatively. The post operative factors included total amount of postoperative blood loss and post operative insertion of IABP. Multivariate analysis of significant factors showed male gender, preoperative anaemia and total duration of surgery were independent predictors of need of blood and blood product transfusion. Prior identification of risk factors and correction of them if applicable would help to assess and manage preoperatively and also thereby reduce the need for blood transfusions and help in managing optimal utilization of resources.


2013 ◽  
Vol 2 (6) ◽  
Author(s):  
M. Hadadzade ◽  
S. Forouzania ◽  
S. Mirhoseini ◽  
H. Peighambari ◽  
N. Naserzade ◽  
...  

2017 ◽  
Vol 8 (1) ◽  
pp. 200-207
Author(s):  
Sarah Farukhi Ahmed ◽  
Audrey Xi Tai ◽  
Mason Schmutz ◽  
John Combs ◽  
Sameh Mosaed

Importance: The purpose of this case report is to evaluate risk factors associated with post-coronary artery bypass graft (CABG) ocular hypotony compared to post-CABG ischemic optic neuropathy. Observations: The patient described here is a single case at the University of California, Irvine Medical Center, from July 2016. This case demonstrates the rare incidence of acute post-CABG ocular hypotony and vision loss in a patient with prior history of optic atrophy. Both vision loss and hypotony resolved completely to baseline without intervention within 3 days postoperatively. Conclusions and Relevance: Severe anemia and large fluctuations in central venous pressure and blood pressure can occur in any patient undergoing CABG surgery. These hemodynamic shifts can cause transient ischemia to pressure controlling systems such as the ciliary body and reduce episcleral venous pressure. Other risk factors for acute hypotony in the setting of CABG surgery also include the use of hypertonic agents, cardiopulmonary bypass, and intravenous anesthesia.


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