scholarly journals Swept Source Optical Coherence Tomography (En-Face) Imaging in Conjunction with (Retinal flow) Optical Coherence Angiography Map “Marking Out” Deep Capillary Plexus Ischemia in Paracentral Acute Middle Maculopathy

2018 ◽  
Vol 1 (1) ◽  
pp. 1-5
Author(s):  
Fawwaz Al-Mamoori ◽  
Mutaz Harara ◽  
Maan Abdullah
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Swept Source ◽  
En Face ◽  
Capillary Plexus ◽  
En Face Imaging

scholarly journals Swept Source Optical Coherence Tomography Assessment of Bursa Premacularis in Healthy Eyes

2020 ◽  
Vol 2020 ◽  
pp. 1-8
Author(s):  
Paolo Carpineto ◽  
Rossella D’Aloisio ◽  
Daniele Guarini ◽  
Carla Iafigliola ◽  
Luca Cerino ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Intraclass Correlation ◽  
Optical Coherence ◽  
High Definition ◽  
Swept Source ◽  
Visualization Software ◽  
En Face ◽  
Bursa Premacularis ◽  
Youth Population ◽  
En Face Imaging

Purpose. To describe the reliability and the limits of bursa premacularis (BPM) evaluation using a swept source optical coherence tomography (SS-OCT) device with enface and 16 mm-high definition (HD) longitudinal scans. Methods. 60 eyes of 60 subjects were enrolled and imaged with SS-OCT system (PLEX Elite 9000, Carl Zeiss Meditec Inc., Dublin, CA, USA). BPM area was measured using enface scans imported to ImageJ. HD horizontal and vertical longitudinal scans centered at the fovea were used to detect width (W) and central thickness (CT) of BPM at baseline (T0) and after 30 minutes (T30) performed by two different observers. An enhanced vitreous visualization software provided by the manufacturer of the device was used to highlight vitreous structures. Results. BPM was identifiable in 100% of eyes using both horizontal and vertical longitudinal scans. On horizontal scan, BPM was not entirely measurable in 21.7% and in 18.3% of cases at T0 and T30, respectively. On vertical scan, BPM was not entirely measurable in 75.0% and in 81.7% at T0 and T30, respectively. No statistically significant differences were found between the two different time measurements with an intraclass correlation coefficient above 70%. Median BPM area was 26.9 (Q1-Q3: 19.5-40.5) mm2. In en face imaging, the most frequent BPM shape was the boat one. Conclusion. SS-OCT is a reliable tool for a detailed quantification and mapping of BPM, and it is able to add useful details about the morphological BPM features in youth population. However, the enhanced visualization of the vitreous structures is still a challenge, also with the most forefront devices.

EN FACE IMAGING OF PACHYCHOROID SPECTRUM DISORDERS WITH SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY

Retina ◽  
2016 ◽  
Vol 36 (3) ◽  
pp. 499-516 ◽  
Author(s):  
Kunal K. Dansingani ◽  
Chandrakumar Balaratnasingam ◽  
Jonathan Naysan ◽  
K. Bailey Freund
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence ◽  
Swept Source ◽  
En Face ◽  
Spectrum Disorders ◽  
En Face Imaging

Swept source optical coherence tomography angiography in patients treated with hydroxychloroquine: correlation with morphological and functional tests

2019 ◽  
pp. bjophthalmol-2018-313679 ◽  
Author(s):  
Raimondo Forte ◽  
Hanan Haulani ◽  
Agnieszka Dyrda ◽  
Ignasi Jürgens
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Fundus Autofluorescence ◽  
Foveal Avascular Zone ◽  
Optical Coherence ◽  
Swept Source ◽  
Retinal Capillary ◽  
En Face ◽  
Capillary Plexus ◽  
Healthy Control

PurposeTo evaluate swept source optical coherence tomography angiography (SS-OCTA) in patients treated with hydroxychloroquine (HCQ) for more than 5 years and to compare results with the tests currently recommended for screening of HCQ retinopathy.MethodsIn this controlled pilot study, consecutive patients treated with HCQ for more than 5 years underwent SS-OCTA, SS-OCT B-scan and en-face C-scan, fundus autofluorescence (FAF), 10–2 automated visual field (AVF) testing and multifocal electroretinography (mfERG). On SS-OCTA, evaluation of the retinal superficial capillary plexus, middle capillary plexus, and deep capillary plexus (DCP) and the choriocapillaris (CC) was obtained.ResultsWe included 10 patients under HCQ treatment (20 eyes, mean age 38.91±11.73 years) and 18 healthy control patients (36 eyes, mean age 38.87±8.6 years). Mean duration of HCQ treatment was 10.0±3.25 (5–15) years and HCQ cumulative dose/body weight was 15.86±5.56 g/kg. The HCQ group showed a reduction of the vessel density in the 1 mm central, in the nasal and temporal subfields of DCP and in the 1 mm central subfield of CC, an increased foveal avascular zone in the three capillary plexuses, a greater frequency of CC flow voids and a reduced foveal choroidal thickness (p<0.05). Best-corrected visual acuity (BCVA), mfERG, SS-OCT B-scan and C-scan, AVF and FAF were normal in 20/20 eyes (100%).ConclusionsIn patients treated with HCQ for more than 5 years, choroidal thinning and flow abnormalities at SS-OCTA in the retinal capillary plexuses and CC may be observed even if BCVA, FAF, mfERG, AVF and SS-OCT are normal.

scholarly journals Optical coherence tomography angiography for the detection of macular neovascularization—comparison of en face versus cross-sectional view

Eye ◽  
2022 ◽  
Author(s):  
Robert Siggel ◽  
Christel Spital ◽  
Anna Lentzsch ◽  
Sandra Liakopoulos
Keyword(s):  
Optical Coherence Tomography ◽  
Sensitivity And Specificity ◽  
Optical Coherence Tomography Angiography ◽  
Optical Coherence ◽  
Cross Sectional ◽  
Swept Source ◽  
Face Images ◽  
En Face ◽  
En Face Imaging ◽  
Subretinal Hyperreflective Material

Abstract Purpose To evaluate sensitivity and specificity of swept source-optical coherence tomography angiography (SS-OCTA) en face images versus cross-sectional OCTA versus a combination of both for the detection of macular neovascularization (MNV). Design Prospective cohort study. Participants Consecutive patients with various chorioretinal diseases and subretinal hyperreflective material (SHRM) and/or pigment epithelial detachment (PED) on OCT possibly corresponding to MNV in at least one eye. Methods 102 eyes of 63 patients with fluorescein angiography (FA), OCT and SS-OCTA performed on the same day were included. FA images, the outer retina to choriocapillaris (ORCC) OCTA en face slab, a manually modified en face slab (‘custom slab’), cross-sectional OCTA and a combination of OCTA en face and cross-section were evaluated for presence of MNV. Main outcome measures Sensitivity and specificity for MNV detection, as well as the concordance was calculated using FA as the reference. Results OCTA en face imaging alone yielded a sensitivity of 46.3% (automated)/78.1% (custom) and specificity of 93.4% (automated)/88.5% (custom) for MNV detection. Cross-sectional OCTA (combination with en face) resulted in a sensitivity of 85.4% (82.9%) and specificity of 82.0% (85.3%). Concordance to FA was moderate for automated en face OCTA (κ = 0.43), and substantial for custom en face OCTA (κ = 0.67), cross-sectional OCTA (κ = 0.66) and the combination (κ = 0.68). Conclusion Segmentation errors result in decreased sensitivity for MNV detection on automatically generated OCTA en face images. Cross-sectional OCTA allows detection of MNV without manual modification of segmentation lines and should be used for evaluation of MNV on OCTA.

scholarly journals Evaluation of vascular changes in intermediate uveitis and retinal vasculitis using swept-source wide-field optical coherence tomography angiography

2018 ◽  
Vol 103 (9) ◽  
pp. 1289-1295 ◽  
Author(s):  
Meng Tian ◽  
Christoph Tappeiner ◽  
Martin S Zinkernagel ◽  
Wolfgang Huf ◽  
Sebastian Wolf ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Optical Coherence Tomography Angiography ◽  
Retinal Vasculitis ◽  
Wide Field ◽  
Optical Coherence ◽  
Intermediate Uveitis ◽  
Vascular Changes ◽  
Swept Source ◽  
En Face ◽  
Capillary Plexus

PurposeTo evaluate vascular changes in patients with intermediate uveitis with or without retinal vasculitis using swept-source wide-field optical coherence tomography angiography (OCTA).MethodsThis is a prospective cross-sectional study. Consecutive patients with intermediate uveitis were evaluated using wide-field OCTA. Wide-field OCTA and en-face OCT images were analysed for the presence of capillary non-perfusion and reduced perfusion, disruption of ellipsoid zone, and abnormalities on en-face wide-field retinal thickness maps, respectively, and compared with fluorescein angiography (FA) findings in a subcohort.Results164 eyes of 88 patients with intermediate uveitis were included. Areas of capillary non-perfusion and reduced perfusion were more frequently observed in the choroidal OCTA slab (33.3% and 49.4%), choriocapillaris (CC; 31.4% and 48%) and deep capillary plexus (DCP; 9.6% and 34.6%) than in the superficial capillary plexus (SCP; 5% and 26.3%), respectively. Intermediate uveitis with vasculitis presented more frequently with non-perfusion and hypoperfusion in the DCP (p=0.003 and p=0.05, respectively) and SCP (p=0.007 and p=0.005, respectively) than intermediate uveitis without vasculitis. Peripheral capillary leakage on FA correlated with the presence of perivascular, macular and generalised thickening on en-face wide-field thickness maps (p=0.007). Ischaemia on FA was significantly associated with non-perfusion on wide-field OCTA in SCP and DCP (p=0.019 and p=0.027, respectively).ConclusionChanges in the choroid, CC and DCP are more frequently found than in the SCP on wide-field OCTA in intermediate uveitis. While wide-field OCTA is a reliable tool to detect capillary non-perfusion in intermediate uveitis, it was not helpful in determining disease activity.Trial registration numberNCT02811536.

scholarly journals En Face Imaging of the Choroid in Polypoidal Choroidal Vasculopathy Using Swept-Source Optical Coherence Tomography

2015 ◽  
Vol 159 (4) ◽  
pp. 634-643.e2 ◽  
Author(s):  
Tarek Alasil ◽  
Daniela Ferrara ◽  
Mehreen Adhi ◽  
Erika Brewer ◽  
Martin F. Kraus ◽  
...  
Keyword(s):  
Optical Coherence Tomography ◽  
Polypoidal Choroidal Vasculopathy ◽  
Optical Coherence ◽  
Swept Source ◽  
En Face ◽  
Choroidal Vasculopathy ◽  
En Face Imaging
Sign in / Sign up

Export Citation Format

Share Document