Invasive mole mimicking as AV malformation

Choriocarcinoma is a rare neoplasm and a malignant form of gestational trophoblastic disease. Invasive mole may perforate uterus through the myometrium resulting in uterine perforation and intraperitoneal bleeding. But uterine perforation due to choriocarcinoma is rare. We present a case of a young woman who presented 1 year after uterine evacuation of a molar pregnancy with invasive choriocarcinoma complicated by a uterine rupture and haemoperitoneum.

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Gestational trophoblastic neoplasia: Retrospective analysis of clinical profile, treatment pattern and outcome

10.1055/s-0039-1685377 ◽

2016 ◽

Author(s):

Paramjeet Kaur ◽

Ashok K. Chauhan ◽

Anil Khurana ◽

Yashpal Verma ◽

Nupur Bansal

Keyword(s):

High Risk ◽

Risk Group ◽

Hydatidiform Mole ◽

Single Agent ◽

High Risk Group ◽

Treatment Pattern ◽

Gestational Trophoblastic Neoplasia ◽

Trophoblastic Tumor ◽

Villous Trophoblast ◽

Invasive Mole

Background: Gestational trophoblastic disease is a spectrum of cellular proliferation arising from the placental villous trophoblast. Gestational triphoblastic neoplasia (GTN) is a collective term for GTD that invade locally or metastasize. GTD includes hydatidiform mole (complete and partial) and GTN include invasive mole, choricocarcinoma, placental site trophoblastic tumor and epitheliod trophoblastic tumor. Aim: To evaluate clinicopathological profile, treatment pattern and clinical outcome in patients with gestational trophoblastic neoplasia (GTN). Materials and Methods: Twelve cases of gestational trophoblastic neoplasia treated between 2012 to November 2015 in deptt of Radiotherapy – II, PGIMS, Rohtak were evaluated in this retrospective study. Data was analyzed on the basis of age, histopathology, stage, type of treatment received and treatment related toxicities. Disease free survival was estimated. Results: Out of 12 women 7 (58 %) had hydatidiform mole, 4 (33%) invasive mole and 01 (8%) had choriocarcinoma. All the cases were given chemotherapy. Two patients had low risk disease. Among high risk group seven patients had score of less than 7 and five patients had risk score of 7 or higher. Five patients were given single agent methotrexate, seven patients received multidrug regimens. All patients are on regular follow up. One patient (high risk group) expired as she did not receive treatment. Conclusion: GTN are rare and proliferative disorders with proper diagnosis and treatment most of the cases are amenable to treatment with favorable outcome.

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Uterine Artery Embolisation for Post-partum Haemorrhage Associated with Placenta Accreta and AV Malformation: Case Report and Review of Literature

10.1055/s-0041-1729831 ◽

2017 ◽

Author(s):

Mohamad S Hamady

Keyword(s):

Case Report ◽

Uterine Artery ◽

Placenta Accreta ◽

Post Partum ◽

Uterine Artery Embolisation ◽

Review Of Literature ◽

Av Malformation ◽

Post Partum Haemorrhage

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Rubeosis iridis and macular hemorrhages from multiple Corkscrew retinal vessels in a patient with NF1

European Journal of Ophthalmology ◽

10.1177/1120672121996636 ◽

2021 ◽

pp. 112067212199663

Author(s):

Marilyn A Márquez ◽

Claudio P Juárez ◽

Maria C Sánchez ◽

Jose D Luna

Keyword(s):

Intravitreal Bevacizumab ◽

Visual Outcome ◽

Neovascular Glaucoma ◽

Retinal Vessels ◽

Retinal Hemorrhages ◽

Fluorescein Angiogram ◽

Rubeosis Iridis ◽

Good Visual Outcome ◽

Av Malformation ◽

Sudden Decrease

Purpose: To report a case of a patient with NF1 presenting with ocular findings of AV malformation, multiple retinal hemorrhages, and neovascular glaucoma in the absence of retinal ischemia. Methods: Review of the medical record was conducted in accordance with the local IRBt. Results: A 60-year-old female patient with diagnosis of Neurofibromatosis type1 (NF1) and sudden decrease of vision in her left eye was found to have rubeosis iridis and high intraocular pressure (IOP). On fundus exam multiple corkscrew retinal vessels and retinal hemorrhages were present in her left eye. On Optical Coherence Tomography (OCT) the foveal hemorrhages appeared as outer layer hyperreflective retinal infiltrates whereas in the parafoveal area the hyperreflectivity was present between the RPE and neurosensory retina. Fluorescein Angiogram (FA) showed normal perfusion and no areas of leakage or ischemia. Treatment with anti-angiogenics in a timely manner correlated with a good visual outcome. Conclusions: We present a unique patient with NF1, rubeosis iridis, high IOP, and macular hemorrhages from multiple corkscrew retinal vessels in a well perfused retina, who underwent treatment with a single dose of intravitreal Bevacizumab and had an excellent response

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Invasive mole

European Journal of Obstetrics & Gynecology and Reproductive Biology ◽

10.1016/0028-2243(86)90034-1 ◽

1986 ◽

Vol 21 (3) ◽

pp. 181-185

Author(s):

H.R. Franke ◽

J.B. Vermorken ◽

H.v. Kessel ◽

G.H. Dijkhuizen ◽

J.J. Calame ◽

...

Keyword(s):

Invasive Mole

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A Case of Invasive Mole

Faridpur Medical College Journal ◽

10.3329/fmcj.v12i2.34236 ◽

2017 ◽

Vol 12 (2) ◽

pp. 86-87

Author(s):

Shahana Ahmed ◽

Dipti Rani Shaha

Keyword(s):

Hydatidiform Mole ◽

The Body ◽

Emergency Laparotomy ◽

Molar Pregnancy ◽

Complete Hydatidiform Mole ◽

Partial Hydatidiform Mole ◽

Normal Limits ◽

History Of ◽

Invasive Mole

Invasive mole is a condition where a molar pregnancy, such as a partial hydatidiform mole or complete hydatidiform mole, invades the wall of the uterus, potentially spreading and metastasizing to other parts of the body. Here is a case who presented with history of evacuation for molar pregnancy. She presented with irregular P/V bleeding on and off and after admission silent perforation with massive haemoperitoneum was detected for which emergency laparotomy was done. She recovered and was followed up till her b-hCG levels were within normal limits. As patient presented to us with haemoperitoneum and on laparotomy, there was invasion into whole of the uterus, it could not be saved and hysterectomy was done.Faridpur Med. Coll. J. Jul 2017;12(2): 86-87

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