scholarly journals Report From the 6th International Meeting on Bone Marrow Adiposity (BMA2020)

2021 ◽  
Vol 12 ◽  
Author(s):  
Erica L. Scheller ◽  
Meghan E. McGee-Lawrence ◽  
Beata Lecka-Czernik

The 6th International Meeting on Bone Marrow Adiposity (BMA) entitled “Marrow Adiposity: Bone, Aging, and Beyond” (BMA2020) was held virtually on September 9th and 10th, 2020. The mission of this meeting was to facilitate communication and collaboration among scientists from around the world who are interested in different aspects of bone marrow adiposity in health and disease. The BMA2020 meeting brought together 198 attendees from diverse research and clinical backgrounds spanning fields including bone biology, endocrinology, stem cell biology, metabolism, oncology, aging, and hematopoiesis. The congress featured an invited keynote address by Ormond MacDougald and ten invited speakers, in addition to 20 short talks, 35 posters, and several training and networking sessions. This report summarizes and highlights the scientific content of the meeting and the progress of the working groups of the BMA society (http://bma-society.org/).

2019 ◽  
Vol 10 ◽  
Author(s):  
Alessandro Corsi ◽  
Biagio Palmisano ◽  
Josefine Tratwal ◽  
Mara Riminucci ◽  
Olaia Naveiras

2019 ◽  
Vol 10 ◽  
Author(s):  
Guillaume Penel ◽  
Greet Kerckhofs ◽  
Christophe Chauveau

2011 ◽  
Vol 212 (2) ◽  
pp. 169-178 ◽  
Author(s):  
Emin Umit Bagriacik ◽  
Melek Yaman ◽  
Rauf Haznedar ◽  
Gulsan Sucak ◽  
Tuncay Delibasi

Bone marrow-derived mesenchymal stem cells are pluripotent cells that are capable of differentiating into a variety of cell types including neuronal cells, osteoblasts, chondrocytes, myocytes, and adipocytes. Despite recent advances in stem cell biology, neuroendocrine relations, particularly TSH interactions remain elusive. In this study, we investigated expression and biological consequence of TSH receptor (TSHR) interactions in mesenchymal stem cells of cultured human bone marrow. To the best of our knowledge, we demonstrated for the first time that human bone marrow-derived mesenchymal stem cells expressed a functional thyrotropin receptor that was capable of transducing signals through cAMP. We extended this study to explore possible pathways that could be associated directly or indirectly with the TSHR function in mesenchymal stem cells. Expression of 80 genes was studied by real-time PCR array profiles. Our investigation indicated involvements of interactions between TSH and its receptor in novel regulatory pathways, which could be the important mediators of self-renewal, maintenance, development, and differentiation in bone marrow-derived mesenchymal stem cells. TSH enhanced differentiation to the chondrogenic cell lineage; however, further work is required to determine whether osteoblastic differentiation is also promoted. Our results presented in this study have opened an era of regulatory events associated with novel neuroendocrine interactions of hypothalamic–pituitary axis in mesenchymal stem cell biology and differentiation.


Biomolecules ◽  
2021 ◽  
Vol 11 (11) ◽  
pp. 1660
Author(s):  
Darius Widera

Multipotent mesenchymal stem cells/marrow stromal cells (MSCs), originally discovered in the bone marrow by Alexander Friedenstein as early as 1968 [...]


2018 ◽  
Vol 22 (4) ◽  
pp. 2311-2318 ◽  
Author(s):  
Marie Bill ◽  
Peter B. van Kooten Niekerk ◽  
Petter S. Woll ◽  
Laura Laine Herborg ◽  
Anne Stidsholt Roug ◽  
...  

Author(s):  
Karen-Sue B. Carlson ◽  
Joshua Morris ◽  
Lauryn P. Cross ◽  
Sridhar Rao

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