scholarly journals Compulsivity in Alcohol Use Disorder and Obsessive Compulsive Disorder: Implications for Neuromodulation

Author(s):  
Elisabetta Burchi ◽  
Nikolaos Makris ◽  
Mary R. Lee ◽  
Stefano Pallanti ◽  
Eric Hollander
CNS Spectrums ◽  
2020 ◽  
pp. 1-8 ◽  
Author(s):  
Gabriela M. Ferreira ◽  
Rico S.C. Lee ◽  
Marcelo Piquet-Pessôa ◽  
Gabriela B. de Menezes ◽  
Maria E. Moreira-de-Oliveira ◽  
...  

Abstract Objective. To (1) confirm whether the Habit, Reward, and Fear Scale is able to generate a 3-factor solution in a population of obsessive-compulsive disorder and alcohol use disorder (AUD) patients; (2) compare these clinical groups in their habit, reward, and fear motivations; and (3) investigate whether homogenous subgroups can be identified to resolve heterogeneity within and across disorders based on the motivations driving ritualistic and drinking behaviors. Methods. One hundred and thirty-four obsessive-compulsive disorder (n = 76) or AUD (n = 58) patients were assessed with a battery of scales including the Habit, Reward, and Fear Scale, the Yale-Brown Obsessive-Compulsive Scale, the Alcohol Dependence Scale, the Behavioral Inhibition/Activation System Scale, and the Urgency, (lack of ) Premeditation, (lack of ) Perseverance, Sensation Seeking, and Positive Urgency Impulsive Behavior Scale. Results. A 3-factor solution reflecting habit, reward, and fear subscores explained 56.6% of the total variance of the Habit, Reward, and Fear Scale. Although the habit and fear subscores were significantly higher in obsessive-compulsive disorder (OCD) and the reward subscores were significantly greater in AUD patients, a cluster analysis identified that the 3 clusters were each characterized by differing proportions of OCD and AUD patients. Conclusions. While affective (reward- and fear-driven) and nonaffective (habitual) motivations for repetitive behaviors seem dissociable from each other, it is possible to identify subgroups in a transdiagnostic manner based on motivations that do not match perfectly motivations that usually described in OCD and AUD patients.


2009 ◽  
Vol 100 (1-2) ◽  
pp. 173-177 ◽  
Author(s):  
André F. Gentil ◽  
Maria Alice de Mathis ◽  
Ricardo C. Torresan ◽  
Juliana B. Diniz ◽  
Pedro Alvarenga ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document