The topic of this chapter is a body of work from various branches of the cognitive sciences suggesting that the tendency to distinguish qualitatively between bodies and minds—between physical objects subject to mechanical causality and agents capable of free will, planning, and intentionality—is a human cognitive universal. It develops reliably and early in human beings, a genetic inheritance shaped by the powerful adaptive pressures of social living. In addition, there is good evidence that this distinction between objects and agents reliability kicks off mind-body dualism, afterlife and soul beliefs, a perception of “meaning” in the world, and concepts of supernatural agency that share broad features across cultures and throughout history. These universals create suspicion of any claim that the early Chinese were strong mind-body holists. Relevant cognitive universals include Theory of Mind, concepts of psychological interiority, and basic supernatural, afterlife and soul beliefs.