scholarly journals The Role of PET in Supratentorial and Infratentorial Pediatric Brain Tumors

2021 ◽  
Vol 28 (4) ◽  
pp. 2481-2495
Author(s):  
Angelina Cistaro ◽  
Domenico Albano ◽  
Pierpaolo Alongi ◽  
Riccardo Laudicella ◽  
Daniele Antonio Pizzuto ◽  
...  

Objective: This review aims to provide a summary of the clinical indications and limitations of PET imaging with different radiotracers, including 18F-fluorodeoxyglucose (18F-FDG) and other radiopharmaceuticals, in pediatric neuro-oncology, discussing both supratentorial and infratentorial tumors, based on recent literature (from 2010 to present). Methods: A literature search of the PubMed/MEDLINE database was carried out searching for articles on the use of PET in pediatric brain tumors. The search was updated until December 2020 and limited to original studies published in English after 1 January 2010. Results: 18F-FDG PET continues to be successfully employed in different settings in pediatric neuro-oncology, including diagnosis, grading and delineation of the target for stereotactic biopsy, estimation of prognosis, evaluation of recurrence, treatment planning and assessment of treatment response. Nevertheless, non-18F-FDG tracers, especially amino acid analogues seem to show a better performance in each clinical setting. Conclusions: PET imaging adds important information in the diagnostic work-up of pediatric brain tumors. International or national multicentric studies are encouraged in order to collect larger amount of data.

2010 ◽  
Vol 26 (9) ◽  
pp. 1189-1193 ◽  
Author(s):  
Mohamed Ahmed El Beltagy ◽  
Mohamed Aggag ◽  
Mohamed Kamal

2013 ◽  
Vol 54 (8) ◽  
pp. 1237-1243 ◽  
Author(s):  
K. A. Zukotynski ◽  
F. H. Fahey ◽  
S. Vajapeyam ◽  
S. S. Ng ◽  
M. Kocak ◽  
...  

2008 ◽  
Vol 8 (1) ◽  
pp. 121-132 ◽  
Author(s):  
Simon S Lo ◽  
Achilles J Fakiris ◽  
Ramzi Abdulrahman ◽  
Mark A Henderson ◽  
Eric L Chang ◽  
...  

2006 ◽  
Vol 22 (7) ◽  
pp. 652-661 ◽  
Author(s):  
Giuseppe Barone ◽  
Palma Maurizi ◽  
Giampiero Tamburrini ◽  
Riccardo Riccardi

2019 ◽  
Vol 21 (8) ◽  
pp. 968-980 ◽  
Author(s):  
Zachary Miklja ◽  
Amy Pasternak ◽  
Stefanie Stallard ◽  
Theodore Nicolaides ◽  
Cassie Kline-Nunnally ◽  
...  

Abstract As the field of neuro-oncology makes headway in uncovering the key oncogenic drivers in pediatric glioma, the role of precision diagnostics and therapies continues to rapidly evolve with important implications for the standard of care for clinical management of these patients. Four studies at major academic centers were published in the last year outlining the clinically integrated molecular profiling and targeting of pediatric brain tumors; all 4 demonstrated the feasibility and utility of incorporating sequencing into the care of children with brain tumors, in particular for children and young adults with glioma. Based on synthesis of the data from these studies and others, we provide consensus recommendations for the integration of precision diagnostics and therapeutics into the practice of pediatric neuro-oncology. Our primary consensus recommendation is that next-generation sequencing should be routinely included in the workup of most pediatric gliomas.


2020 ◽  
Vol 62 (6) ◽  
pp. 705-713
Author(s):  
Simona Gaudino ◽  
Giammaria Marziali ◽  
Giovanna Pezzullo ◽  
Pamela Guadalupi ◽  
Carolina Giordano ◽  
...  

2006 ◽  
Vol 22 (11) ◽  
pp. 1435-1439 ◽  
Author(s):  
Peter Kan ◽  
James K. Liu ◽  
Gary Hedlund ◽  
Douglas L. Brockmeyer ◽  
Marion L. Walker ◽  
...  

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