Development and Effects of College-Based Lifestyle Modification Program for Menstrual Health of Young Adult Women with Irregular Menses: A Randomized Controlled Trial

Purpose: This study was conducted to develop the ‘College-based Lifestyle Modification Program’ (College-based LMP) for young adult women with irregular menstruation and examine its effects after intervention. Methods: The College-based LMP consisted of small group education, individual physical exercise counseling/training, individual diet counseling, and feedback and support. Participants were comprised of 38 females who reported less than 10 irregular menstruations in a year and were randomly assigned to the experimental and control groups. The primary outcome variables consisted of menstrual cycle index (MCI), sex hormone binding globulin (SHBG), and androgenic profile (testosterone—T, free androgen index—FAI), while the outcome variables included premenstrual symptoms (PMS), menstrual volume, body composition parameters, glycemic parameters (fasting blood sugar—FBS, insulin, HOMA-IR), sleep duration, perceived stress, and nutrient intake.. Results: There were no significant differences in primary outcome variables (MCI, SHBG, T, and FAI). In the variables, there were no significant differences except for the partial domain of PMS (symptoms of depression and anxiety) and sleep duration. Conclusions: The study was significant in that it demonstrated the importance of lifestyle, which could provide ordinary young adult women with healthy menstruation. The College-based LMP needs to be elaborated with further studies.

Download Full-text

PCOS Features and Steroid Profiles Among Young Adult Women with a History of Premature Adrenarche

The Journal of Clinical Endocrinology & Metabolism ◽

10.1210/clinem/dgab385 ◽

2021 ◽

Author(s):

Jussi Tennilä ◽

Jarmo Jääskeläinen ◽

Pauliina Utriainen ◽

Raimo Voutilainen ◽

Merja Häkkinen ◽

...

Keyword(s):

Young Adult ◽

Ovarian Function ◽

Polycystic Ovary ◽

Sex Hormone Binding Globulin ◽

Hormonal Contraceptives ◽

Adult Women ◽

Young Adult Women ◽

Premature Adrenarche ◽

Steroid Profiles ◽

History Of

Abstract Context Premature adrenarche (PA) may increase the risk for polycystic ovary syndrome (PCOS). Objective To study features of PCOS in young adult women with a history of PA. Design and participants Thirty PA and forty-two control females were followed from prepuberty to young adulthood (median age 18.1 years). Main outcome measures Ovarian function, the use of contraceptives, and clinical and biochemical indicators of hyperandrogenism. Results We found no differences in the use of hormonal contraceptives (50 vs 50%, PA vs controls, respectively; P > .999), indication for using contraceptives (P = .193), or in the history of oligo- (17 vs 26%, P = .392) and amenorrhea (0 vs 0%, P > .999). Among women not using hormonal contraceptives, those with a history of PA had a higher prevalence of hirsutism (27 vs 0%, P = .023) but not acne (87 vs 67%, P = .252). Steroid profiles were broadly comparable between the groups, but PA women had lower sex hormone-binding globulin (SHBG) concentrations (30.1 vs 62.4 nmol/l, P < .001) resulting in higher free androgen index (3.94 vs 2.14, P < .001). The difference in SHBG levels persisted through BMI adjustment. SHBG correlated negatively with HOMA-IR (r -0.498, P = .003). Anti-Mullerian hormone concentrations were comparable between the groups (39.3 vs. 32.1 pmol/l, P = .619). Conclusions PA was not associated with evident ovarian dysfunction in young adult women. However, women with a history of PA had decreased SHBG levels and thus, increased bioavailability of circulating androgens.

Download Full-text

Online prevention of disordered eating in at-risk young-adult women: a two-country pragmatic randomized controlled trial

Psychological Medicine ◽

10.1017/s0033291717003567 ◽

2017 ◽

Vol 48 (12) ◽

pp. 2034-2044 ◽

Cited By ~ 13

Author(s):

Simon M. Wilksch ◽

Anne O'Shea ◽

C. Barr Taylor ◽

Denise Wilfley ◽

Corinna Jacobi ◽

...

Keyword(s):

Body Image ◽

Randomized Controlled Trial ◽

Young Adult ◽

Disordered Eating ◽

Controlled Trial ◽

Adult Women ◽

Young Adult Women ◽

Pragmatic Randomized Controlled Trial ◽

Randomized Controlled

AbstractBackgroundDisordered eating (DE) is a widespread, serious problem. Efficacious prevention programs that can be delivered at-scale are needed.MethodsA pragmatic randomized controlled trial of two online programs was conducted. Participants were young-adult women from Australia and New Zealand seeking to improve their body image. Media Smart-Targeted (MS-T) and Student Bodies (SB) were both 9-module interventions released weekly, whilst control participants received positive body image information. Primary [Eating Disorder Examination–Questionnaire (EDE-Q) Global], secondary (DE risk factors) and tertiary (DE) outcome measures were completed at baseline, post-program, 6- and 12-month follow-up.ResultsBaseline was completed by 608 women (M age = 20.71 years); 33 were excluded leaving 575 randomized to: MS-T (N = 191); SB (N = 190) or control (N = 194). Only 66% of those randomized to MS-T or SB accessed the intervention and were included in analyses with controls; 78% of this sample completed measures subsequent to baseline. Primary intent-to-treat (ITT) analyses revealed no differences between groups, while measure completer analyses found MS-T had significantly lower EDE-Q Global than controls at 12-month follow-up. Secondary ITT analyses found MS-T participants reported significantly higher quality of life–mental relative to both SB and controls (6-month follow-up), while MS-T and controls had lower clinical impairment relative to SB (post-program). Amongst measure completers, MS-T scored significantly lower than controls and SB on 5 variables. Of those with baseline DE, MS-T participants were significantly less likely than controls to have DE at 12-month follow-up.ConclusionsGiven both programs were not therapist-moderated, MS-T has potential to achieve reductions in DE risk at low implementation costs.

Download Full-text