scholarly journals Urogynaecological Symptoms among Oncological Survivors and Impact of Oncological Treatment on Pelvic Floor Disorders and Lower Urinary Tract Symptoms. A Six-Month Follow-Up Study

2020 ◽  
Vol 9 (9) ◽  
pp. 2804
Author(s):  
Alicja Ziętek-Strobl ◽  
Konrad Futyma ◽  
Izabela Kuna-Broniowska ◽  
Małgorzata Wojtaś ◽  
Tomasz Rechberger

It has been widely underlined that both gynaecological malignancies and urogynaecological disorders are often associated with high stress and have a negative impact on the quality of life and psychological well-being of women affected. Knowledge of the pelvic anatomy is crucial in recommending and carrying out the least harmful although successful treatment. Subsequent chemoradiation may also induce or exaggerate troublesome symptoms. The aim of the study was to establish the frequency of urogynaecological symptoms (stress urinary incontinence, urgency, pelvic organ prolapse) and to assess the impact of surgical treatment and additional oncological therapy: pelvic radiation, chemoradiation, chemotherapy, on the prevalence of pelvic floor dysfunctions (PFD) and lower urinary tract symptoms (LUTS) in patients suffering from gynecological malignancies. The study group consisted of 160 women, diagnosed with gynaecological malignancy, who underwent surgical treatment and additional adjuvant treatment as necessary. To establish the QoL and prevalence of PFD Urinary Distress Inventory-6 (UDI-6), Incontinence Impact Questionnaire 7 (II-Q7), King’s Health Questionnaire (KHQ) and the SF-36 Questionnaire were used. Herein, 69 patients reported urinary incontinence (UI) and 67 reported symptoms of pelvic organ prolapse (POP). After the six months follow-up UI was found in 78 patients, 25 patients showed de novo symptoms, 65 patients reported POP and 10 patients demonstrated de novo POP. Our data show that urogynaecological symptoms are not correlated with the type of malignancy, but with the extensiveness of surgery.

Author(s):  
Nanthini Saravanan ◽  
Aruna N. Kekre ◽  
Mahasampath Gowri S.

Background: The objective of the present study was to observe the post void residual volume (PVRV) in women with pelvic organ prolapse (POP) pre and postoperatively and to correlate stage of prolapse with lower urinary tract symptoms and quality of life in women with pelvic organ prolapse.Methods: This is a prospective observational cohort study of 100 women with symptomatic pelvic organ prolapse of stage II or greater. Patients were admitted for Vaginal hysterectomy with pelvic floor repair for pelvic organ prolapse in Gynaecology Department at Christian Medical College Hospital, Vellore, India over one year were recruited. This study was approved by the institutional review board and ethical committee of the hospital. Pre- and post-operative PVR were measured. The statistical analysis was done by using SPSS version 21 and P value < 0.05 was considered as statistically significant.Results: In this study 100 patients were recruited and 11% of women had pre-operative high post void residual volume of more than 100 ml. Stages of POP did not correlate with severity of LUTS and QOL. Pre-operative elevated PVR resolved post operatively in 91%, the P value <0.000 which was highly significant.Conclusions: 11% of women had preoperative high PVR. Stages of POP did not correlate with severity of lower urinary tract symptoms (LUTS) and quality of life(QOL). Pre-operative elevated PVR resolved post operatively in 91%, the P value < 0.000 which was highly significant. Majority of the patient with severe pelvic organ prolapse had elevated pre-op PVR which resolved post- operatively after surgical correction.


2012 ◽  
Vol 79 (1) ◽  
pp. 19-23 ◽  
Author(s):  
Elisabetta Costantini ◽  
Massimo Lazzeri ◽  
Massimo Porena

Background Female pelvic organ prolapse (POP) is a common condition that often leads to lower urinary tract symptoms (LUTS) and may require surgical intervention to alleviate those symptoms. However, tThe relationship between LUTS and pelvic organ descent however, remains unclear. The aim of this paper is to determine the correlation between LUTS and POP and changes after POP repair. Methods We retrospectively review female patients who attended our tertiary high- volume centre center for LUTS and POP, and underwent integral pelvic floor reconstruction. Results An overall of 256 patients presented with POP and LUTS and underwent POP repair. Most of 50% of patients reported two or more symptoms and only 4.2% were asymptomatic for LUTS. 189/256 (73.8%) patients had voiding symptoms and 39 a urodynamic detrusor overactivity. Thirteen suffered from hydronephrosis. 148/256 (57.8%) showed a stress urinary incontinence. All the patients underwent POP repair with or without contemporary anti- incontinence procedure. Conclusions Urologists and gynaecologists should recognisebe aware of the high frequency of the POP and LUTS association of POP and LUTS. POP repair my restore a normal situation but symptoms may last after the surgery or develop “de novo.”


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