(R,S)-5-(4-Chlorophenyl)-3-{(E)-2-[(R,S)-2,6,6-trimethylcyclohex-2-en-1-yl]vinyl}-4,5-dihydro-1H-pyrazole-1-carboximidamide Hydrochloride

Pyrazoline and amidine motifs are important in medicinal chemistry due to their broad spectrum of bioactivities. This work’s goal was to synthesize a new hybrid amidino pyrazoline from terpenyl chalcone. The chosen method consists of making the terpenyl chalcone react with aminoguanidine hydrochloride in the presence of potassium hydroxide using ethanol as solvent. The reaction was carried out under ultrasonic irradiation. The resulting terpenyl amidino pyrazoline was isolated after separation in a silica-gel chromatographic column in 86% of yield. The product structure was confirmed by the analysis of the high resolution mass, 1H and 13C-NMR spectra. The data was consistent with the expected structure. In summary, the method was efficient for the synthesis of a new hybrid terpenyl amidino pyrazolines under sonochemical conditions.

Download Full-text

2-Hydroxy-3-octyloxybenzaldehyde

Molbank ◽

10.3390/m1264 ◽

2021 ◽

Vol 2021 (3) ◽

pp. M1264

Author(s):

Julia V. Novoselova ◽

Anatoliy A. Vereshchagin ◽

Arseniy Y. Kalnin ◽

Daniil A. Lukyanov ◽

Oleg V. Levin

Keyword(s):

Mass Spectrometry ◽

Fourier Transform ◽

Infrared Spectroscopy ◽

High Resolution ◽

13C Nmr ◽

Nmr Spectra ◽

High Resolution Mass Spectrometry ◽

13C Nmr Spectra ◽

1H And 13C Nmr ◽

Resolution Mass

Herein, we report the chromatography-free synthesis of 2-hydroxy-3-octyloxybenzaldehyde by the alkylation of 2,3-dihydroxybenzaldehyde as a promising precursor for new SalEn-type complexes with transition metals. The structure of the product is elucidated by means of 1H and 13C-NMR spectra, high-resolution mass spectrometry with electrospray ionization (ESI-HRMS) and Fourier-transform infrared spectroscopy (FTIR).

Download Full-text

Specific Changes in the High Resolution 1H and 13C NMR Spectra of Triethyl- and Trimethylacetic Acids at the Liquid-Solid Phase Transition

Molecular Crystals and Liquid Crystals ◽

10.1080/01406567908071972 ◽

1979 ◽

Vol 56 (3) ◽

pp. 83-88 ◽

Cited By ~ 4

Author(s):

Liudvikas L. Kimtys

Keyword(s):

Phase Transition ◽

High Resolution ◽

13C Nmr ◽

Nmr Spectra ◽

Solid Phase ◽

13C Nmr Spectra ◽

1H And 13C Nmr ◽

Solid Phase Transition

Download Full-text

Specifity of High Resolution 1H and 13C NMR Spectra of Solid Fatty Carboxylic Acids

Molecular Crystals and Liquid Crystals ◽

10.1080/01406567908070476 ◽

1979 ◽

Vol 56 (1) ◽

pp. 25-30 ◽

Cited By ~ 4

Author(s):

Liuovikas L. Kimtys

Keyword(s):

High Resolution ◽

Carboxylic Acids ◽

13C Nmr ◽

Nmr Spectra ◽

13C Nmr Spectra ◽

1H And 13C Nmr

Download Full-text

Some Considerations Regarding the 1H and 13C Spectra of 4-(1-azulenyl)-2,6-bis(2-heteroaryl-vinyl)- pyrylium and Pyridinium and their Corresponding Pyridines

Revista de Chimie ◽

10.37358/rc.18.1.6045 ◽

2018 ◽

Vol 69 (1) ◽

pp. 64-69

Author(s):

Liviu Birzan ◽

Mihaela Cristea ◽

Constantin C. Draghici ◽

Alexandru C. Razus

Keyword(s):

Double Bond ◽

13C Nmr ◽

Nmr Spectra ◽

Chemical Shifts ◽

Pyridinium Salts ◽

13C Nmr Spectra ◽

1H And 13C Nmr ◽

Pyrylium Salts

The 1H and 13C NMR spectra of several 2,6-diheteroarylvinyl heterocycles containing 4-azulenyl moiety were recorded and their proton and carbon chemical shifts were compared with those of the compounds without double bond between the heterocycles. The influence of the nature of central and side heterocycles, molecule polarization and anisotropic effects were revealed. The highest chemical shifts were recorded for the pyrylium salts and the lowest at pyridines, but in the case of the pyridinium salts, the protons chemical shifts at the central heterocycle are more shielded due to a peculiar anisotropy of the attached vinyl groups.

Download Full-text