scholarly journals Full Viral Genome Sequencing and Phylogenomic Analysis of Feline Herpesvirus Type 1 (FHV-1) in Cheetahs (Acinonyx jubatus)

Viruses ◽  
2021 ◽  
Vol 13 (11) ◽  
pp. 2307
Author(s):  
Morgan E. Marino ◽  
Melanie A. Mironovich ◽  
Nikole E. Ineck ◽  
Scott B. Citino ◽  
Jessica A. Emerson ◽  
...  

Feline herpesvirus type 1 (FHV-1) is endemic in captive cheetahs and sporadically causes devastating disease. Modified live vaccines (MLV), intended for use in domestic cats, are used in some captive cheetah populations and have been anecdotally linked to disease in certain subpopulations. Ten FHV-1 isolates from ten captive cheetahs and one isolate from an MLV used to inoculate four of the host animals were analyzed. Viral DNA was extracted for full-genome sequencing by Illumina MiSeq with viral genomes then used for phylogenomic and recombinational analyses. The FHV-1 shed by vaccinated cheetahs were almost identical to the MLV, with few variants among viral genomes. Eight cheetah FHV-1 isolates and the MLV were grouped in a clade along with FHV-1 isolates from domestic cats in the USA. The remaining two cheetah FHV-1 isolates (unknown host vaccine status) were not associated with a clade. The likely ancestral origin of these two isolates involves recombination events between Australian domestic cat and cheetah FHV-1 isolates. Collectively, these data suggest that the MLV is capable of causing clinical disease and viral shedding in some cheetahs and represents evidence of interspecies transmission of virus between domestic and wild cats.

1991 ◽  
Vol 28 (4) ◽  
pp. 338-340 ◽  
Author(s):  
J. W. Kramer ◽  
J. F. Evermann ◽  
C. W. Leathers ◽  
A. J. McKeirnan ◽  
L. Rashti

1992 ◽  
Vol 126 (1-4) ◽  
pp. 283-292 ◽  
Author(s):  
T. Horimoto ◽  
J. A. Limcumpao ◽  
X. Xuan ◽  
M. Ono ◽  
K. Maeda ◽  
...  

1986 ◽  
Vol 41 (3) ◽  
pp. 323-330 ◽  
Author(s):  
F.M. COCKER ◽  
T.J. NEWBY ◽  
R.M. GASKELL ◽  
P.A. EVANS ◽  
C.J. GASKELL ◽  
...  

1991 ◽  
Vol 53 (3) ◽  
pp. 423-432 ◽  
Author(s):  
Joselito A. LIMCUMPAO ◽  
Taisuke HORIMOTO ◽  
Xuenan XUAN ◽  
Yukinobu TOHYA ◽  
Masayuki AZETAKA ◽  
...  

1995 ◽  
Vol 39 (1) ◽  
pp. 55-61 ◽  
Author(s):  
Ken Maeda ◽  
Kensuke Hirasawa ◽  
Yasushi Kawaguchi ◽  
Mitsuru Ono ◽  
Takeshi Mori ◽  
...  

2002 ◽  
Vol 88 (2) ◽  
pp. 144-149 ◽  
Author(s):  
Masayuki Mishima ◽  
Xuenan Xuan ◽  
Naoaki Yokoyama ◽  
Ikuo Igarashi ◽  
Kozo Fujisaki ◽  
...  

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