Faculty Opinions recommendation of Click chemistry in situ: acetylcholinesterase as a reaction vessel for the selective assembly of a femtomolar inhibitor from an array of building blocks.

Author(s):  
Jon Thorson
2002 ◽  
Vol 114 (6) ◽  
pp. 1095-1099 ◽  
Author(s):  
Warren G. Lewis ◽  
Luke G. Green ◽  
Flavio Grynszpan ◽  
Zoran Radić ◽  
Paul R. Carlier ◽  
...  

Author(s):  
D.E. Brownlee ◽  
A.L. Albee

Comets are primitive, kilometer-sized bodies that formed in the outer regions of the solar system. Composed of ice and dust, comets are generally believed to be relic building blocks of the outer solar system that have been preserved at cryogenic temperatures since the formation of the Sun and planets. The analysis of cometary material is particularly important because the properties of cometary material provide direct information on the processes and environments that formed and influenced solid matter both in the early solar system and in the interstellar environments that preceded it.The first direct analyses of proven comet dust were made during the Soviet and European spacecraft encounters with Comet Halley in 1986. These missions carried time-of-flight mass spectrometers that measured mass spectra of individual micron and smaller particles. The Halley measurements were semi-quantitative but they showed that comet dust is a complex fine-grained mixture of silicates and organic material. A full understanding of comet dust will require detailed morphological, mineralogical, elemental and isotopic analysis at the finest possible scale. Electron microscopy and related microbeam techniques will play key roles in the analysis. The present and future of electron microscopy of comet samples involves laboratory study of micrometeorites collected in the stratosphere, in-situ SEM analysis of particles collected at a comet and laboratory study of samples collected from a comet and returned to the Earth for detailed study.


2021 ◽  
Vol 3 (3) ◽  
pp. 1602-1609
Author(s):  
Flavia Lupi ◽  
Daniele Martella ◽  
Sara Nocentini ◽  
Diego Antonioli ◽  
Michele Laus ◽  
...  

2021 ◽  
Author(s):  
Max Schütz ◽  
Christian Gemel ◽  
Maximilian Muhr ◽  
Christian Jandl ◽  
Samia Kahlal ◽  
...  

Cu/Al cluster growth reactions leading to open- and closed-shell superatoms are investigated. Therein, LIFDI-MS is presented as a powerful technique for the in situ detection of cluster identities and reactivity patterns.


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