Faculty Opinions recommendation of Identification of eukaryotic promoter regulatory elements using nonhomologous random recombination.

Author(s):  
Steven Spiker
2020 ◽  
Vol 49 (D1) ◽  
pp. D1046-D1057 ◽  
Author(s):  
Jairo Navarro Gonzalez ◽  
Ann S Zweig ◽  
Matthew L Speir ◽  
Daniel Schmelter ◽  
Kate R Rosenbloom ◽  
...  

Abstract For more than two decades, the UCSC Genome Browser database (https://genome.ucsc.edu) has provided high-quality genomics data visualization and genome annotations to the research community. As the field of genomics grows and more data become available, new modes of display are required to accommodate new technologies. New features released this past year include a Hi-C heatmap display, a phased family trio display for VCF files, and various track visualization improvements. Striving to keep data up-to-date, new updates to gene annotations include GENCODE Genes, NCBI RefSeq Genes, and Ensembl Genes. New data tracks added for human and mouse genomes include the ENCODE registry of candidate cis-regulatory elements, promoters from the Eukaryotic Promoter Database, and NCBI RefSeq Select and Matched Annotation from NCBI and EMBL-EBI (MANE). Within weeks of learning about the outbreak of coronavirus, UCSC released a genome browser, with detailed annotation tracks, for the SARS-CoV-2 RNA reference assembly.


2015 ◽  
Vol 364 ◽  
pp. 364-376 ◽  
Author(s):  
Roohollah Shamloo-Dashtpagerdi ◽  
Hooman Razi ◽  
Massumeh Aliakbari ◽  
Angelica Lindlöf ◽  
Mahdi Ebrahimi ◽  
...  

2015 ◽  
Vol 37 (s1) ◽  
pp. 87-105
Author(s):  
Benedek Nobilis ◽  
András Svraka

Governments throughout the EU and OECD countries rely on revenues raised on capital income. Albeit several arguments can be made for keeping these taxes, in their widespread form they hinder capital accumulation and significantly lower potential growth due to their savings and investment distorting nature. At the same time, the actual economic impact of tax types is largely influenced by their structure. An elegant method, which is also simple in its concept, for eliminating the economic distortions of profit taxes is cash-flow taxation which moves income taxes closer to the more growth-friendly value-added taxes. The small business tax, which was introduced in Hungary in 2013, was designed along these principles. In this paper we review the theoretical literature on cash-flow taxation and discuss the main regulatory elements of the small business tax, as well as the solutions elaborated for working out the challenges related to its implementation.


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