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Faculty Opinions recommendation of Phase III, double-blind, randomized study comparing lapatinib plus paclitaxel with placebo plus paclitaxel as first-line treatment for metastatic breast cancer.
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
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10.3410/f.1128881.585979
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2008
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Author(s):
Carmelo Bengala
Keyword(s):
Breast Cancer
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Metastatic Breast Cancer
◽
Randomized Study
◽
Metastatic Breast
◽
Phase Iii
◽
Line Treatment
◽
First Line
◽
Double Blind
◽
First Line Treatment
Download Full-text
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Abstract OT1-1-06: A phase III randomized study of Paclitaxel and Trastuzumab versus Paclitaxel, Trastuzumab and Lapatinib in first line treatment of HER2 positive metastatic breast cancer.
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Clinical Benefit Rate and Time to Response in RIBBON-1, a Randomized, Double-Blind, Phase III Trial of Chemotherapy with or without Bevacizumab (B) for the First-Line Treatment of HER2-Negative Locally Recurrent or Metastatic Breast Cancer (MBC).
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MARIANNE: A phase III, randomized study of trastuzumab-DM1 (T-DM1) with or without pertuzumab (P) compared with trastuzumab (H) plus taxane for first-line treatment of HER2-positive, progressive, or recurrent locally advanced or metastatic breast cancer (MBC).
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◽
10.1016/s1359-6349(09)70908-5
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Bendamustine prolongs progression-free survival in metastatic breast cancer (MBC): a phase III prospective, randomized, multicenter trial of bendamustine hydrochloride, methotrexate and 5-fluorouracil (BMF) versus cyclophosphamide, methotrexate and 5-fluorouracil (CMF) as first-line treatment of MBC
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First Line
◽
Her2 Positive
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Phase Iii Study
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Trastuzumab Monotherapy
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