Faculty Opinions recommendation of Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function.

2009 ◽  
Author(s):  
Ross Cagan
Keyword(s):  
Metastasis Suppressor ◽  
Suppressor Function

scholarly journals Identification of a gene expression signature associated with the metastasis suppressor function of NME1: prognostic value in human melanoma

2017 ◽  
Vol 98 (3) ◽  
pp. 327-338 ◽  
Author(s):  
M Kathryn Leonard ◽  
Joseph R McCorkle ◽  
Devin E Snyder ◽  
Marian Novak ◽  
Qingbei Zhang ◽  
...  
Keyword(s):  
Gene Expression ◽  
Prognostic Value ◽  
Gene Expression Signature ◽  
Human Melanoma ◽  
Metastasis Suppressor ◽  
Expression Signature ◽  
Suppressor Function

scholarly journals Functional genomics of lung cancer progression reveals mechanism of metastasis suppressor function

2014 ◽  
Vol 7 (Suppl 1) ◽  
pp. I9 ◽  
Author(s):  
Ram Thakur ◽  
Vinod Kumar Yadav ◽  
Akinchan Kumar ◽  
Richa Basundra ◽  
Anirban Kar ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Functional Genomics ◽  
Cancer Progression ◽  
Metastasis Suppressor ◽  
Suppressor Function

scholarly journals Metastasis suppressor function of NM23-H1 requires its 3′-5′ exonuclease activity

2010 ◽  
Vol 128 (1) ◽  
pp. 40-50 ◽  
Author(s):  
Qingbei Zhang ◽  
Joseph R. McCorkle ◽  
Marian Novak ◽  
Mengmeng Yang ◽  
David M. Kaetzel
Keyword(s):  
Metastasis Suppressor ◽  
Exonuclease Activity ◽  
Suppressor Function

Multiple mechanisms underlie metastasis suppressor function of NM23-H1 in melanoma

2011 ◽  
Vol 384 (4-5) ◽  
pp. 433-438 ◽  
Author(s):  
Marian Novak ◽  
Stuart G. Jarrett ◽  
Joseph R. McCorkle ◽  
Isabel Mellon ◽  
David M. Kaetzel
Keyword(s):  
Metastasis Suppressor ◽  
Suppressor Function

scholarly journals Src phosphorylation of RhoGDI2 regulates its metastasis suppressor function

2009 ◽  
Vol 106 (14) ◽  
pp. 5807-5812 ◽  
Author(s):  
Y. Wu ◽  
K. Moissoglu ◽  
H. Wang ◽  
X. Wang ◽  
H. F. Frierson ◽  
...  
Keyword(s):  
Metastasis Suppressor ◽  
Suppressor Function

scholarly journals Emerging Molecular Connections between NM23 Proteins, Telomeres and Telomere-Associated Factors: Implications in Cancer Metastasis and Ageing

2021 ◽  
Vol 22 (7) ◽  
pp. 3457
Author(s):  
Shalu Sharma ◽  
Antara Sengupta ◽  
Shantanu Chowdhury
Keyword(s):  
Associated Factors ◽  
Cellular Differentiation ◽  
Cancer Metastasis ◽  
Enzymatic Activities ◽  
Signalling Pathways ◽  
Metastasis Suppressor ◽  
Related Factors ◽  
Suppressor Function ◽  
Recent Developments

The metastasis suppressor function of NM23 proteins is widely understood. Multiple enzymatic activities of NM23 proteins have also been identified. However, relatively less known interesting aspects are being revealed from recent developments that corroborate the telomeric interactions of NM23 proteins. Telomeres are known to regulate essential physiological events such as metastasis, ageing, and cellular differentiation via inter-connected signalling pathways. Here, we review the literature on the association of NM23 proteins with telomeres or telomere-related factors, and discuss the potential implications of emerging telomeric functions of NM23 proteins. Further understanding of these aspects might be instrumental in better understanding the metastasis suppressor functions of NM23 proteins.

scholarly journals Potential contributions of antimutator activity to the metastasis suppressor function of NM23-H1

2009 ◽  
Vol 329 (1-2) ◽  
pp. 161-165 ◽  
Author(s):  
David M. Kaetzel ◽  
Joseph R. McCorkle ◽  
Marian Novak ◽  
Mengmeng Yang ◽  
Stuart G. Jarrett
Keyword(s):  
Metastasis Suppressor ◽  
Suppressor Function

VAMP8, a vesicle-SNARE required for RAB37-mediated exocytosis, possesses a tumor metastasis suppressor function

2018 ◽  
Vol 437 ◽  
pp. 79-88 ◽  
Author(s):  
Yu-Shiuan Wang ◽  
Hong-Tai Tzeng ◽  
Chung-Han Tsai ◽  
Hung-Chi Cheng ◽  
Wu-Wei Lai ◽  
...  
Keyword(s):  
Tumor Metastasis ◽  
Metastasis Suppressor ◽  
Suppressor Function
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