Faculty Opinions recommendation of Relationships between vancomycin minimum inhibitory concentration, dosing strategies, and outcomes in methicillin-resistant Staphylococcus aureus bacteremia.

2012 ◽  
Author(s):  
Philippe Lagacé-Wiens
Keyword(s):  
Staphylococcus Aureus ◽  
Minimum Inhibitory Concentration ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Inhibitory Concentration ◽  
Methicillin Resistant ◽  
Staphylococcus Aureus Bacteremia ◽  
Vancomycin Minimum Inhibitory Concentration ◽  
Dosing Strategies

Impact of Vancomycin Minimum Inhibitory Concentration on Mortality among Critically Ill Patients witn Methicillin-Resistant Staphylococcus aureus Bacteremia

2012 ◽  
Vol 33 (12) ◽  
pp. 1246-1249 ◽  
Author(s):  
Christian J. Woods ◽  
Anindita Chowdhury ◽  
Vinay M. Patel ◽  
Andrew F. Shorr
Keyword(s):  
Staphylococcus Aureus ◽  
Minimum Inhibitory Concentration ◽  
Odds Ratio ◽  
Adjusted Odds Ratio ◽  
Methicillin Resistant Staphylococcus Aureus ◽  
Inhibitory Concentration ◽  
Methicillin Resistant ◽  
Staphylococcus Aureus Bacteremia ◽  
Vancomycin Minimum Inhibitory Concentration ◽  
Probability Of Death

We retrospectively evaluated 99 intensive care unit patients with methicillin-resistant Staphylococcus aureus bacteremia to determine whether having a vancomycin minimum inhibitory concentration (MIC) of 2 mg/L affected mortality. This MIC was found in 5.1% of patients and was associated with the probability of death (adjusted odds ratio, 13.9 [95% confidence interval, 1.1–171.2]) independent of other factors.

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