Faculty Opinions recommendation of Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

2014 ◽  
Author(s):  
Mark Gilbert
Keyword(s):  
Kinase Inhibitors ◽  
Molecular Determinants ◽  
Egfr Kinase

Molecular Determinants of the Response of Glioblastomas to EGFR Kinase Inhibitors

2005 ◽  
Vol 353 (19) ◽  
pp. 2012-2024 ◽  
Author(s):  
Ingo K. Mellinghoff ◽  
Maria Y. Wang ◽  
Igor Vivanco ◽  
Daphne A. Haas-Kogan ◽  
Shaojun Zhu ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Molecular Determinants ◽  
Egfr Kinase

scholarly journals Platination of cysteine by an epidermal growth factor receptor kinase-targeted hybrid agent

2018 ◽  
Vol 54 (54) ◽  
pp. 7479-7482 ◽  
Author(s):  
Mu Yang ◽  
Hanzhi Wu ◽  
Julie Chu ◽  
Lucas A. Gabriel ◽  
Y. Kim ◽  
...  
Keyword(s):  
Epidermal Growth Factor Receptor ◽  
Growth Factor ◽  
Epidermal Growth Factor ◽  
Kinase Inhibitors ◽  
Growth Factor Receptor ◽  
Cysteine Residue ◽  
Receptor Kinase ◽  
Epidermal Growth ◽  
Hybrid Agent ◽  
Egfr Kinase

Platinum-modified tyrosine kinase inhibitors show strong and selective EGFR kinase binding and form adducts with a pharmacologically relevant cysteine residue.

scholarly journals Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFRL858R/T790M/C797S

2019 ◽  
Vol 10 (6) ◽  
pp. 869-873 ◽  
Author(s):  
Qiannan Li ◽  
Tao Zhang ◽  
Shiliang Li ◽  
Linjiang Tong ◽  
Junyu Li ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Egfr Kinase

Design, synthesis and biological evaluation of potent EGFR kinase inhibitors against 19D/T790M/C797S mutation

2020 ◽  
Vol 30 (16) ◽  
pp. 127327
Author(s):  
Zhicheng Su ◽  
Tingyuan Yang ◽  
Jie Wang ◽  
Mengzhen Lai ◽  
Linjiang Tong ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation ◽  
Egfr Kinase

scholarly journals Differential Sensitivity of Glioma- versus Lung Cancer–Specific EGFR Mutations to EGFR Kinase Inhibitors

2012 ◽  
Vol 2 (5) ◽  
pp. 458-471 ◽  
Author(s):  
Igor Vivanco ◽  
H. Ian Robins ◽  
Daniel Rohle ◽  
Carl Campos ◽  
Christian Grommes ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Kinase Inhibitors ◽  
Differential Sensitivity ◽  
Egfr Mutations ◽  
Egfr Kinase
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